HDAC inhibitors elicit metabolic reprogramming by targeting super-enhancers in glioblastoma models TTT Nguyen, Y Zhang, E Shang, C Shu, C Torrini, J Zhao, E Bianchetti, ... The Journal of clinical investigation 130 (7), 3699-3716, 2020 | 146 | 2020 |
Ribosome profiling reveals a cell-type-specific translational landscape in brain tumors C Gonzalez, JS Sims, N Hornstein, A Mela, F Garcia, L Lei, DA Gass, ... Journal of Neuroscience 34 (33), 10924-10936, 2014 | 131 | 2014 |
Quantitative assessment of protein activity in orphan tissues and single cells using the metaVIPER algorithm H Ding, EF Douglass Jr, AM Sonabend, A Mela, S Bose, C Gonzalez, ... Nature communications 9 (1), 1471, 2018 | 128 | 2018 |
PRMT5-mediated regulation of developmental myelination A Scaglione, J Patzig, J Liang, R Frawley, J Bok, A Mela, C Yattah, ... Nature Communications 9 (1), 2840, 2018 | 95 | 2018 |
Glioma-induced alterations in neuronal activity and neurovascular coupling during disease progression MK Montgomery, SH Kim, A Dovas, HT Zhao, AR Goldberg, W Xu, ... Cell reports 31 (2), 2020 | 86 | 2020 |
Dietary restriction of cysteine and methionine sensitizes gliomas to ferroptosis and induces alterations in energetic metabolism PS Upadhyayula, DM Higgins, A Mela, M Banu, A Dovas, F Zandkarimi, ... Nature Communications 14 (1), 1187, 2023 | 78 | 2023 |
Focused ultrasound-mediated blood-brain barrier opening increases delivery and efficacy of etoposide for glioblastoma treatment HJ Wei, PS Upadhyayula, AN Pouliopoulos, ZK Englander, X Zhang, ... International Journal of Radiation Oncology* Biology* Physics 110 (2), 539-550, 2021 | 73 | 2021 |
Aurora kinase A inhibition reverses the Warburg effect and elicits unique metabolic vulnerabilities in glioblastoma TTT Nguyen, E Shang, C Shu, S Kim, A Mela, N Humala, A Mahajan, ... Nature communications 12 (1), 5203, 2021 | 72 | 2021 |
Lactate is an epigenetic metabolite that drives survival in model systems of glioblastoma C Torrini, TTT Nguyen, C Shu, A Mela, N Humala, A Mahajan, EH Seeley, ... Molecular cell 82 (16), 3061-3076. e6, 2022 | 54 | 2022 |
The tetraspanin KAI1/CD82 is expressed by late-lineage oligodendrocyte precursors and may function to restrict precursor migration and promote oligodendrocyte differentiation … A Mela, JE Goldman Journal of Neuroscience 29 (36), 11172-11181, 2009 | 48 | 2009 |
Neonatal and adult O4+ oligodendrocyte lineage cells display different growth factor responses and different gene expression patterns G Lin, A Mela, EM Guilfoyle, JE Goldman Journal of neuroscience research 87 (15), 3390-3402, 2009 | 47 | 2009 |
MET inhibition elicits PGC1α-dependent metabolic reprogramming in glioblastoma Y Zhang, TTT Nguyen, E Shang, A Mela, N Humala, A Mahajan, J Zhao, ... Cancer research 80 (1), 30-43, 2020 | 44 | 2020 |
Targeting S100A9–ALDH1A1–Retinoic Acid Signaling to Suppress Brain Relapse in EGFR-Mutant Lung Cancer AK Biswas, S Han, Y Tai, W Ma, C Coker, SA Quinn, AR Shakri, TJ Zhong, ... Cancer discovery 12 (4), 1002-1021, 2022 | 42 | 2022 |
CD8+ T-cell–Mediated Immunoediting Influences Genomic Evolution and Immune Evasion in Murine Gliomas JR Kane, J Zhao, T Tsujiuchi, B Laffleur, VA Arrieta, A Mahajan, G Rao, ... Clinical Cancer Research 26 (16), 4390-4401, 2020 | 36 | 2020 |
Substituting gadolinium in brain MRI using DeepContrast H Sun, X Liu, X Feng, C Liu, N Zhu, SJ Gjerswold-Selleck, HJ Wei, ... 2020 IEEE 17th International Symposium on Biomedical Imaging (ISBI), 908-912, 2020 | 28 | 2020 |
CD82 blocks cMet activation and overcomes hepatocyte growth factor effects on oligodendrocyte precursor differentiation A Mela, JE Goldman Journal of Neuroscience 33 (18), 7952-7960, 2013 | 26 | 2013 |
Vascular-derived SPARC and SerpinE1 regulate interneuron tangential migration and accelerate functional maturation of human stem cell-derived interneurons M Genestine, D Ambriz, GW Crabtree, P Dummer, A Molotkova, ... Elife 10, e56063, 2021 | 13 | 2021 |
Single-cell analysis of 5-aminolevulinic acid intraoperative labeling specificity for glioblastoma Z Liu, A Mela, MG Argenziano, MA Banu, J Furnari, C Kotidis, CP Sperring, ... Journal of Neurosurgery 140 (4), 968-978, 2023 | 10 | 2023 |
A pharmacological toolkit for human microglia identifies Topoisomerase I inhibitors as immunomodulators for Alzheimer’s disease V Haage, JF Tuddenham, N Comandante-Lou, A Bautista, A Monzel, ... bioRxiv, 2024 | 6 | 2024 |
Osteopontin drives neuroinflammation and cell loss in MAPT-N279K frontotemporal dementia patient neurons O Al-Dalahmah, M Lam, JJ McInvale, W Qu, T Nguyen, JY Mun, S Kwon, ... Cell Stem Cell 31 (5), 676-693. e10, 2024 | 5 | 2024 |