The cyclopeptide astin C specifically inhibits the innate immune CDN sensor STING S Li, Z Hong, Z Wang, F Li, J Mei, L Huang, X Lou, S Zhao, L Song, ... Cell reports 25 (12), 3405-3421. e7, 2018 | 181 | 2018 |
4-Octyl itaconate protects against renal fibrosis via inhibiting TGF-β/Smad pathway, autophagy and reducing generation of reactive oxygen species F Tian, Z Wang, J He, Z Zhang, N Tan European journal of pharmacology 873, 172989, 2020 | 60 | 2020 |
Natural cyclopeptide RA-XII, a new autophagy inhibitor, suppresses protective autophagy for enhancing apoptosis through AMPK/mTOR/P70S6K pathways in HepG2 cells L Song, Z Wang, Y Wang, D Guo, J Yang, L Chen, N Tan Molecules 22 (11), 1934, 2017 | 53 | 2017 |
New Cytotoxic Naphthohydroquinone Dimers from Rubia alata SM Zhao, Z Wang, GZ Zeng, WW Song, XQ Chen, XN Li, NH Tan Organic letters 16 (21), 5576-5579, 2014 | 44 | 2014 |
Colletopeptides A–D, Anti-inflammatory Cyclic Tridepsipeptides from the Plant Endophytic Fungus Colletotrichum sp. S8 L Feng, J Wang, S Liu, XJ Zhang, QR Bi, YY Hu, Z Wang, NH Tan Journal of natural products 82 (6), 1434-1441, 2019 | 37 | 2019 |
Rubicordins A–C, new cyclopeptides from Rubia cordifolia with cytotoxicity and inhibiting NF-κB signaling pathway XQ Chen, SM Zhao, Z Wang, GZ Zeng, MB Huang, NH Tan Tetrahedron 71 (52), 9673-9678, 2015 | 36 | 2015 |
Redox dual-responsive and o2‑evolving theranostic nanosystem for highly selective chemotherapy against hypoxic tumors H Chen, F Li, Y Yao, Z Wang, Z Zhang, N Tan Theranostics 9 (1), 90, 2019 | 34 | 2019 |
Natural cyclopeptide RA-V inhibits the NF-κB signaling pathway by targeting TAK1 Z Wang, S Zhao, L Song, Y Pu, Q Wang, G Zeng, X Liu, M Bai, S Li, F Gao, ... Cell death & disease 9 (7), 715, 2018 | 34 | 2018 |
Cyclopeptide RA-V inhibits cell adhesion and invasion in both estrogen receptor positive and negative breast cancer cells via PI3K/AKT and NF-κB signaling pathways HW Leung, Z Wang, GGL Yue, SM Zhao, JKM Lee, KP Fung, PC Leung, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1853 (8), 1827-1840, 2015 | 34 | 2015 |
(±)-Zanthonitidine A, a Pair of Enantiomeric Furoquinoline Alkaloids from Zanthoxylum nitidum with Antibacterial Activity LN Zhao, XX Guo, S Liu, L Feng, QR Bi, Z Wang, NH Tan Natural products and bioprospecting 8, 361-367, 2018 | 32 | 2018 |
RA-XII, a bicyclic hexapeptidic glucoside isolated from Rubia yunnanensis Diels, exerts antitumor activity by inhibiting protective autophagy and activating Akt-mTOR pathway in … J Wang, J Wang, L Li, L Feng, YR Wang, Z Wang, NH Tan Journal of Ethnopharmacology 266, 113438, 2021 | 30 | 2021 |
Discovery of selenium-containing STING agonists as orally available antitumor agents X Feng, L Pan, Z Qian, D Liu, X Guan, L Feng, B Song, X Xu, N Tan, Y Ma, ... Journal of Medicinal Chemistry 65 (22), 15048-15065, 2022 | 27 | 2022 |
1,4-Naphthoquinone Triggers Nematode Lethality by Inducing Oxidative Stress and Activating Insulin/IGF Signaling Pathway in Caenorhabditis elegans J Wang, G Zeng, X Huang, Z Wang, N Tan Molecules 22 (5), 798, 2017 | 26 | 2017 |
Rubipodanin A, the First Natural N-Desmonomethyl Rubiaceae-Type Cyclopeptide from Rubia podantha, Indicating an Important Role of the N9-Methyl Group in … Z Wang, SM Zhao, LM Zhao, XQ Chen, GZ Zeng, NH Tan PLoS One 10 (12), e0144950, 2015 | 26 | 2015 |
Two novel diterpenoid heterodimers, Bisebracteolasins A and B, from Euphorbia ebracteolata Hayata, and the cancer chemotherapeutic potential of … WJ Yuan, X Ding, Z Wang, BJ Yang, XN Li, Y Zhang, DZ Chen, SL Li, ... Scientific reports 7 (1), 14507, 2017 | 25 | 2017 |
Design, synthesis, docking, molecular dynamics and bioevaluation studies on novel N-methylpicolinamide and thienopyrimidine derivatives with inhibiting NF-κB and TAK1 … L Wang, Q Zhang, Z Wang, W Zhu, N Tan European Journal of Medicinal Chemistry 223, 113576, 2021 | 23 | 2021 |
Programmed delivery of cyclopeptide RA-V and antisense oligonucleotides for combination therapy on hypoxic tumors and for therapeutic self-monitoring Y Yao, L Feng, Z Wang, H Chen, N Tan Biomaterials science 8 (1), 256-265, 2020 | 22 | 2020 |
Visible light-initiated manganese-catalyzed hydrosulfonylation of alkenes CM Li, XX Dong, Z Wang, B Zhang Green Chemistry 25 (10), 4122-4128, 2023 | 20 | 2023 |
Cyclopeptide RA-V inhibits organ enlargement and tumorigenesis induced by YAP activation X Ji, L Song, L Sheng, A Gao, Y Zhao, S Han, Y Zhang, C Zhu, S Zhao, ... Cancers 10 (11), 449, 2018 | 20 | 2018 |
NF-κB and JNK mediated apoptosis and G0/G1 arrest of HeLa cells induced by rubiarbonol G, an arborinane-type triterpenoid from Rubia yunnanensis GZ Zeng, Z Wang, LM Zhao, JT Fan, NH Tan Journal of ethnopharmacology 220, 220-227, 2018 | 20 | 2018 |