N-Myc–mediated epigenetic reprogramming drives lineage plasticity in advanced prostate cancer A Berger, NJ Brady, R Bareja, B Robinson, V Conteduca, MA Augello, ... The Journal of clinical investigation 129 (9), 3924-3940, 2019 | 170 | 2019 |
The E3 ubiquitin ligase Wwp2 regulates craniofacial development through mono-ubiquitylation of Goosecoid W Zou, X Chen, JH Shim, Z Huang, N Brady, D Hu, R Drapp, K Sigrist, ... Nature cell biology 13 (1), 59-65, 2011 | 120 | 2011 |
Macrophages: regulators of the inflammatory microenvironment during mammary gland development and breast cancer NJ Brady, P Chuntova, KL Schwertfeger Mediators of inflammation 2016 (1), 4549676, 2016 | 98 | 2016 |
Activation of the FGFR–STAT3 pathway in breast cancer cells induces a hyaluronan-rich microenvironment that licenses tumor formation LR Bohrer, P Chuntova, LK Bade, TC Beadnell, RP Leon, NJ Brady, ... Cancer research 74 (1), 374-386, 2014 | 85 | 2014 |
Posttranslationally modified progesterone receptors direct ligand-specific expression of breast cancer stem cell-associated gene programs TP Knutson, TH Truong, S Ma, NJ Brady, ME Sullivan, G Raj, ... Journal of Hematology & Oncology 10, 1-24, 2017 | 84 | 2017 |
JAK/STAT inhibition in macrophages promotes therapeutic resistance by inducing expression of protumorigenic factors EA Irey, CM Lassiter, NJ Brady, P Chuntova, Y Wang, TP Knutson, ... Proceedings of the National Academy of Sciences 116 (25), 12442-12451, 2019 | 81 | 2019 |
Clinical accuracy outcomes of closed-tray and open-tray implant impression techniques for partially edentulous patients. GO Gallucci, P Papaspyridakos, LM Ashy, GE Kim, NJ Brady, HP Weber, ... International Journal of Prosthodontics 24 (5), 2011 | 75 | 2011 |
SMURF2 regulates bone homeostasis by disrupting SMAD3 interaction with vitamin D receptor in osteoblasts Z Xu, MB Greenblatt, G Yan, H Feng, J Sun, S Lotinun, N Brady, R Baron, ... Nature communications 8 (1), 14570, 2017 | 73 | 2017 |
The FGF/FGF receptor axis as a therapeutic target in breast cancer NJ Brady, P Chuntova, LK Bade, KL Schwertfeger Expert review of endocrinology & metabolism 8 (4), 391-402, 2013 | 72 | 2013 |
Temporal evolution of cellular heterogeneity during the progression to advanced AR-negative prostate cancer NJ Brady, AM Bagadion, R Singh, V Conteduca, L Van Emmenis, E Arceci, ... Nature communications 12 (1), 3372, 2021 | 71 | 2021 |
MLK3 regulates bone development downstream of the faciogenital dysplasia protein FGD1 in mice W Zou, MB Greenblatt, JH Shim, S Kant, B Zhai, S Lotinun, N Brady, ... The Journal of clinical investigation 121 (11), 2011 | 66 | 2011 |
Schnurri-3 regulates ERK downstream of WNT signaling in osteoblasts JH Shim, MB Greenblatt, W Zou, Z Huang, MN Wein, N Brady, D Hu, ... The Journal of clinical investigation 123 (9), 4010-4022, 2013 | 60 | 2013 |
The microtubule-associated protein DCAMKL1 regulates osteoblast function via repression of Runx2 W Zou, MB Greenblatt, N Brady, S Lotinun, B Zhai, H de Rivera, A Singh, ... Journal of Experimental Medicine 210 (9), 1793-1806, 2013 | 60 | 2013 |
The collection of NFATc1-dependent transcripts in the osteoclast includes numerous genes non-essential to physiologic bone resorption JF Charles, F Coury, R Sulyanto, D Sitara, J Wu, N Brady, K Tsang, ... Bone 51 (5), 902-912, 2012 | 51 | 2012 |
Extracellular matrix in synthetic hydrogel‐based prostate cancer organoids regulate therapeutic response to EZH2 and DRD2 inhibitors MJ Mosquera, S Kim, R Bareja, Z Fang, S Cai, H Pan, M Asad, ML Martin, ... Advanced Materials 34 (2), 2100096, 2022 | 43 | 2022 |
Tumor cell associated hyaluronan-CD44 signaling promotes pro-tumor inflammation in breast cancer PM Witschen, TS Chaffee, NJ Brady, DN Huggins, TP Knutson, RS LaRue, ... Cancers 12 (5), 1325, 2020 | 40 | 2020 |
Epiregulin contributes to breast tumorigenesis through regulating matrix metalloproteinase 1 and promoting cell survival M Farooqui, LR Bohrer, NJ Brady, P Chuntova, SE Kemp, CT Wardwell, ... Molecular cancer 14, 1-13, 2015 | 40 | 2015 |
Breast cancer cell-derived fibroblast growth factors enhance osteoclast activity and contribute to the formation of metastatic lesions K Aukes, C Forsman, NJ Brady, K Astleford, N Blixt, D Sachdev, ... PloS one 12 (10), e0185736, 2017 | 37 | 2017 |
STAT5 is activated in macrophages by breast cancer cell-derived factors and regulates macrophage function in the tumor microenvironment EA Jesser, NJ Brady, DN Huggins, PM Witschen, CH O’Connor, ... Breast Cancer Research 23, 1-17, 2021 | 31 | 2021 |
Administration of BMP2/7 in utero partially reverses Rubinstein-Taybi syndrome–like skeletal defects induced by Pdk1 or Cbp mutations in mice JH Shim, MB Greenblatt, A Singh, N Brady, D Hu, R Drapp, W Ogawa, ... The Journal of clinical investigation 122 (1), 91-106, 2012 | 31 | 2012 |