LSD1: biologic roles and therapeutic targeting A Maiques-Diaz, TCP Somervaille Epigenomics 8 (8), 1103-1116, 2016 | 214 | 2016 |
Enhancer activation by pharmacologic displacement of LSD1 from GFI1 induces differentiation in acute myeloid leukemia A Maiques-Diaz, GJ Spencer, JT Lynch, F Ciceri, EL Williams, ... Cell reports 22 (13), 3641-3659, 2018 | 195 | 2018 |
DNA methylation profiles and their relationship with cytogenetic status in adult acute myeloid leukemia S Alvarez, J Suela, A Valencia, A Fernández, M Wunderlich, X Agirre, ... PloS one 5 (8), e12197, 2010 | 112 | 2010 |
An atlas of cells in the human tonsil R Massoni-Badosa, S Aguilar-Fernández, JC Nieto, P Soler-Vila, ... Immunity 57 (2), 379-399. e18, 2024 | 56 | 2024 |
Development of (4-cyanophenyl) glycine derivatives as reversible inhibitors of lysine specific demethylase 1 DP Mould, C Alli, U Bremberg, S Cartic, AM Jordan, M Geitmann, ... Journal of Medicinal Chemistry 60 (19), 7984-7999, 2017 | 49 | 2017 |
Pre-clinical activity of combined LSD1 and mTORC1 inhibition in MLL-translocated acute myeloid leukaemia G Deb, B Wingelhofer, FMR Amaral, A Maiques-Diaz, JA Chadwick, ... Leukemia 34 (5), 1266-1277, 2020 | 40 | 2020 |
The molecular pathogenesis of the NUP98-HOXA9 fusion protein in acute myeloid leukemia A Rio-Machin, G Gómez-López, J Muñoz, F Garcia-Martinez, ... Leukemia 31 (9), 2000-2005, 2017 | 40 | 2017 |
Chromatin modifications induced by the AML1-ETO fusion protein reversibly silence its genomic targets through AML1 and Sp1 binding motifs A Maiques-Diaz, FS Chou, M Wunderlich, G Gomez-Lopez, FV Jacinto, ... Leukemia 26 (6), 1329-1337, 2012 | 40 | 2012 |
Downregulation of RUNX1/CBFβ by MLL fusion proteins enhances hematopoietic stem cell self-renewal X Zhao, A Chen, X Yan, Y Zhang, F He, Y Hayashi, Y Dong, Y Rao, B Li, ... Blood, The Journal of the American Society of Hematology 123 (11), 1729-1738, 2014 | 37 | 2014 |
Therapeutic targeting of EP300/CBP by bromodomain inhibition in hematologic malignancies L Nicosia, GJ Spencer, N Brooks, FMR Amaral, NJ Basma, JA Chadwick, ... Cancer Cell 41 (12), 2136-2153. e13, 2023 | 34 | 2023 |
LSD1 inhibitors disrupt the GFI1 transcription repressor complex A Maiques-Diaz, JT Lynch, GJ Spencer, TCP Somervaille Molecular & cellular oncology 5 (4), e1481813, 2018 | 25 | 2018 |
Development of 5-hydroxypyrazole derivatives as reversible inhibitors of lysine specific demethylase 1 DP Mould, U Bremberg, AM Jordan, M Geitmann, A Maiques-Diaz, ... Bioorganic & Medicinal Chemistry Letters 27 (14), 3190-3195, 2017 | 21 | 2017 |
Viral transduction of primary human lymphoma B cells reveals mechanisms of NOTCH-mediated immune escape M Mangolini, A Maiques-Diaz, S Charalampopoulou, ... Nature Communications 13 (1), 6220, 2022 | 20 | 2022 |
Effect of the COVID-19 pandemic on laboratory and clinical research: a testimony and a call to action from researchers A Kabanova, E Gavriilaki, BW Pelzer, L Brunetti, A Maiques-Diaz Hemasphere 4 (6), e499, 2020 | 18 | 2020 |
Pharmacological inhibitors of LSD1 promote differentiation of myeloid leukemia cells through a mechanism independent of histone demethylation JT Lynch, GJ Spencer, WJ Harris, A Maiques-Díaz, F Ciceri, X Huang, ... Blood 124 (21), 267, 2014 | 10 | 2014 |
Social theatre as a tool for environmental learning processes: a case study from Madrid, Spain A Jiménez-Aceituno, L Medland, A Delgado, A Carballés-Bretón, ... Across the spectrum: Resources for environmental educators, 281-296, 2016 | 8 | 2016 |
Abrogation of RUNX1 gene expression in de novo myelodysplastic syndrome with t (4; 21)(q21; q22) A Rio-Machín, J Menezes, A Maiques-Diaz, X Agirre, BI Ferreira, ... haematologica 97 (4), 534, 2012 | 8 | 2012 |
Robust CRISPR-Cas9 genetic editing of primary chronic lymphocytic leukemia and mantle cell lymphoma cells J Mateos-Jaimez, M Mangolini, A Vidal, M Kulis, D Colomer, E Campo, ... HemaSphere 7 (6), e909, 2023 | 5 | 2023 |
HMG20B stabilizes association of LSD1 with GFI1 on chromatin to confer transcription repression and leukemia cell differentiation block A Maiques-Diaz, L Nicosia, NJ Basma, I Romero-Camarero, F Camera, ... Oncogene 41 (44), 4841-4854, 2022 | 5 | 2022 |
“Long COVID-19” of researchers: what to do next? E Gavriilaki, A Maiques-Diaz HemaSphere 6 (1), e673, 2022 | 5 | 2022 |