Evidence for improved encapsulated pathway behavior in a bacterial microcompartment through shell protein engineering MF Slininger Lee, CM Jakobson, D Tullman-Ercek ACS synthetic biology 6 (10), 1880-1891, 2017 | 86 | 2017 |
Influence of electrostatics on small molecule flux through a protein nanoreactor JE Glasgow, MA Asensio, CM Jakobson, MB Francis, D Tullman-Ercek ACS synthetic biology 4 (9), 1011-1019, 2015 | 77 | 2015 |
A systems-level model reveals that 1, 2-Propanediol utilization microcompartments enhance pathway flux through intermediate sequestration CM Jakobson, D Tullman-Ercek, MF Slininger, NM Mangan PLoS computational biology 13 (5), e1005525, 2017 | 68 | 2017 |
Localization of proteins to the 1, 2-propanediol utilization microcompartment by non-native signal sequences is mediated by a common hydrophobic motif CM Jakobson, EY Kim, MF Slininger, A Chien, D Tullman-Ercek Journal of Biological Chemistry 290 (40), 24519-24533, 2015 | 68 | 2015 |
Quantitative characterization of all single amino acid variants of a viral capsid-based drug delivery vehicle EC Hartman, CM Jakobson, AH Favor, MJ Lobba, E Álvarez-Benedicto, ... Nature communications 9 (1), 1385, 2018 | 59 | 2018 |
Widespread prion-based control of growth and differentiation strategies in Saccharomyces cerevisiae AK Itakura, AK Chakravarty, CM Jakobson, DF Jarosz Molecular cell 77 (2), 266-278. e6, 2020 | 52 | 2020 |
A selection for assembly reveals that a single amino acid mutant of the bacteriophage MS2 coat protein forms a smaller virus-like particle MA Asensio, NM Morella, CM Jakobson, EC Hartman, JE Glasgow, ... Nano letters 16 (9), 5944-5950, 2016 | 50 | 2016 |
De novo design of signal sequences to localize cargo to the 1,2‐propanediol utilization microcompartment CM Jakobson, MF Slininger Lee, D Tullman‐Ercek Protein Science 26 (5), 1086-1092, 2017 | 45 | 2017 |
Dumpster diving in the gut: bacterial microcompartments as part of a host-associated lifestyle CM Jakobson, D Tullman-Ercek PLoS pathogens 12 (5), e1005558, 2016 | 45 | 2016 |
Engineering transcriptional regulation to control Pdu microcompartment formation EY Kim, CM Jakobson, D Tullman-Ercek PloS one 9 (11), e113814, 2014 | 30 | 2014 |
Molecular origins of complex heritability in natural genotype-to-phenotype relationships CM Jakobson, DF Jarosz Cell Systems 8 (5), 363-379. e3, 2019 | 29 | 2019 |
Tuning the catalytic activity of subcellular nanoreactors CM Jakobson, Y Chen, MF Slininger, E Valdivia, EY Kim, ... Journal of Molecular Biology 428 (15), 2989-2996, 2016 | 27 | 2016 |
Organizing biochemistry in space and time using prion-like self-assembly CM Jakobson, DF Jarosz Current opinion in systems biology 8, 16-24, 2018 | 24 | 2018 |
A prion accelerates proliferation at the expense of lifespan DM Garcia, EA Campbell, CM Jakobson, M Tsuchiya, EA Shaw, ... Elife 10, e60917, 2021 | 21 | 2021 |
What has a century of quantitative genetics taught us about nature's genetic tool kit? CM Jakobson, DF Jarosz Annual Review of Genetics 54 (1), 439-464, 2020 | 18 | 2020 |
Spatially organizing biochemistry: choosing a strategy to translate synthetic biology to the factory CM Jakobson, D Tullman-Ercek, NM Mangan Scientific reports 8 (1), 8196, 2018 | 18 | 2018 |
Pervasive function and evidence for selection across standing genetic variation in S. cerevisiae CM Jakobson, R She, DF Jarosz Nature Communications 10 (1), 1222, 2019 | 16 | 2019 |
Hsp90 shapes adaptation by controlling the fitness consequences of regulatory variation CM Jakobson, J Aguilar-Rodríguez, DF Jarosz bioRxiv, 2023 | 6 | 2023 |
Metabolites control stress granule disassembly CM Jakobson, DF Jarosz Nature Cell Biology 23 (10), 1053-1055, 2021 | 2 | 2021 |
The Hsp90 molecular chaperone as a global modifier of the genotype-phenotype-fitness map: an evolutionary perspective J Aguilar-Rodríguez, CM Jakobson, DF Jarosz Journal of Molecular Biology, 168846, 2024 | 1 | 2024 |