Quantitative structure activity relationship studies on the flavonoid mediated inhibition of multidrug resistance proteins 1 and 2 JJ van Zanden, HM Wortelboer, S Bijlsma, A Punt, M Usta, ... Biochemical pharmacology 69 (4), 699-708, 2005 | 232 | 2005 |
Next generation physiologically based kinetic (NG-PBK) models in support of regulatory decision making A Paini, JA Leonard, E Joossens, JGM Bessems, A Desalegn, JL Dorne, ... Computational Toxicology 9, 61-72, 2019 | 133 | 2019 |
Impact of nanoparticle surface functionalization on the protein corona and cellular adhesion, uptake and transport A Abdelkhaliq, M van der Zande, A Punt, R Helsdingen, S Boeren, ... Journal of nanobiotechnology 16, 1-13, 2018 | 113 | 2018 |
Human cytochrome P450 enzyme specificity for the bioactivation of estragole and related alkenylbenzenes SMF Jeurissen, A Punt, MG Boersma, JJP Bogaards, YC Fiamegos, ... Chemical research in toxicology 20 (5), 798-806, 2007 | 103 | 2007 |
Use of physiologically based biokinetic (PBBK) modeling to study estragole bioactivation and detoxification in humans as compared with male rats A Punt, A Paini, MG Boersma, AP Freidig, T Delatour, G Scholz, B Schilter, ... Toxicological sciences 110 (2), 255-269, 2009 | 88 | 2009 |
A physiologically based biokinetic (PBBK) model for estragole bioactivation and detoxification in rat A Punt, AP Freidig, T Delatour, G Scholz, MG Boersma, B Schilter, ... Toxicology and applied pharmacology 231 (2), 248-259, 2008 | 88 | 2008 |
Identification of nevadensin as an important herb-based constituent inhibiting estragole bioactivation and physiology-based biokinetic modeling of its possible in vivo effect W Alhusainy, A Paini, A Punt, J Louisse, A Spenkelink, J Vervoort, ... Toxicology and Applied Pharmacology 245 (2), 179-190, 2010 | 80 | 2010 |
Tutorial on physiologically based kinetic modeling in molecular nutrition and food research IMCM Rietjens, J Louisse, A Punt Molecular nutrition & food research 55 (6), 941-956, 2011 | 79 | 2011 |
Basil extract inhibits the sulfotransferase mediated formation of DNA adducts of the procarcinogen 1′-hydroxyestragole by rat and human liver S9 homogenates and in HepG2 human … SMF Jeurissen, A Punt, T Delatour, IMCM Rietjens Food and Chemical Toxicology 46 (6), 2296-2302, 2008 | 78 | 2008 |
Combining in vitro embryotoxicity data with physiologically based kinetic (PBK) modelling to define in vivo dose–response curves for developmental toxicity of phenol in rat and … M Strikwold, B Spenkelink, RA Woutersen, IMCM Rietjens, A Punt Archives of toxicology 87, 1709-1723, 2013 | 76 | 2013 |
New approach methodologies (NAMs) for human-relevant biokinetics predictions: Meeting the paradigm shift in toxicology towards an animal-free chemical risk assessment A Punt, H Bouwmeester, BJ Blaauboer, S Coecke, B Hakkert, ... Altex 37 (4), 607-622, 2020 | 70 | 2020 |
Tandem Mass Spectrometry Analysis of N2-(trans-Isoestragol-3‘-yl)-2‘-deoxyguanosine as a Strategy to Study Species Differences in Sulfotransferase Conversion … A Punt, T Delatour, G Scholz, B Schilter, PJ van Bladeren, IMCM Rietjens Chemical Research in Toxicology 20 (7), 991-998, 2007 | 69 | 2007 |
A physiologically based biodynamic (PBBD) model for estragole DNA binding in rat liver based on in vitro kinetic data and estragole DNA adduct formation in primary hepatocytes A Paini, A Punt, F Viton, G Scholz, T Delatour, M Marin-Kuan, B Schilter, ... Toxicology and applied pharmacology 245 (1), 57-66, 2010 | 68 | 2010 |
Development of a web-based toolbox to support quantitative in-vitro-to-in-vivo extrapolations (QIVIVE) within nonanimal testing strategies A Punt, N Pinckaers, A Peijnenburg, J Louisse Chemical research in toxicology 34 (2), 460-472, 2020 | 60 | 2020 |
Evaluation of research activities and research needs to increase the impact and applicability of alternative testing strategies in risk assessment practice A Punt, MJWA Schiffelers, GJ Horbach, JJM van de Sandt, ... Regulatory Toxicology and Pharmacology 61 (1), 105-114, 2011 | 56 | 2011 |
Predicting points of departure for risk assessment based on in vitro cytotoxicity data and physiologically based kinetic (PBK) modeling: the case of kidney toxicity induced by … R Abdullah, W Alhusainy, J Woutersen, IMCM Rietjens, A Punt Food and chemical toxicology 92, 104-116, 2016 | 55 | 2016 |
Integrating in vitro data and physiologically based kinetic (PBK) modelling to assess the in vivo potential developmental toxicity of a series of phenols M Strikwold, B Spenkelink, LHJ de Haan, RA Woutersen, A Punt, ... Archives of toxicology 91, 2119-2133, 2017 | 54 | 2017 |
Physiologically based kinetic modeling of bioactivation and detoxification of the alkenylbenzene methyleugenol in human as compared with rat AS Ala'AA, B Spenkelink, A Punt, MG Boersma, PJ van Bladeren, ... Toxicology and applied pharmacology 260 (3), 271-284, 2012 | 52 | 2012 |
Non-animal approaches for toxicokinetics in risk evaluations of food chemicals A Punt, AACM Peijnenburg, RLAP Hoogenboom, H Bouwmeester ALTEX-Alternatives to animal experimentation 34 (4), 501-514, 2017 | 51 | 2017 |
Conversion of major soy isoflavone glucosides and aglycones in in vitro intestinal models MA Islam, A Punt, B Spenkelink, AJ Murk, FX Rolaf van Leeuwen, ... Molecular nutrition & food research 58 (3), 503-515, 2014 | 50 | 2014 |