| An integrative genomics approach to infer causal associations between gene expression and disease EE Schadt, J Lamb, X Yang, J Zhu, S Edwards, D GuhaThakurta, ... Nature genetics 37 (7), 710-717, 2005 | 1250 | 2005 |
| Mapping the genetic architecture of gene expression in human liver EE Schadt, C Molony, E Chudin, K Hao, X Yang, PY Lum, A Kasarskis, ... PLoS biology 6 (5), e107, 2008 | 1207 | 2008 |
| Variations in DNA elucidate molecular networks that cause disease Y Chen, J Zhu, PY Lum, X Yang, S Pinto, DJ MacNeil, C Zhang, J Lamb, ... Nature 452 (7186), 429-435, 2008 | 1087 | 2008 |
| Tissue-specific expression and regulation of sexually dimorphic genes in mice X Yang, EE Schadt, S Wang, H Wang, AP Arnold, L Ingram-Drake, ... Genome research 16 (8), 995-1004, 2006 | 972 | 2006 |
| Relationship of paraoxonase 1 (PON1) gene polymorphisms and functional activity with systemic oxidative stress and cardiovascular risk T Bhattacharyya, SJ Nicholls, EJ Topol, R Zhang, X Yang, D Schmitt, X Fu, ... Jama 299 (11), 1265-1276, 2008 | 679 | 2008 |
| Co-regulatory networks of human serum proteins link genetics to disease V Emilsson, M Ilkov, JR Lamb, N Finkel, EF Gudmundsson, R Pitts, ... Science 361 (6404), 769-773, 2018 | 530 | 2018 |
| Impact of type 2 diabetes susceptibility variants on quantitative glycemic traits reveals mechanistic heterogeneity AS Dimas, V Lagou, A Barker, JW Knowles, R Mägi, MF Hivert, A Benazzo, ... Diabetes 63 (6), 2158-2171, 2014 | 401 | 2014 |
| Dosage compensation is less effective in birds than in mammals Y Itoh, E Melamed, X Yang, K Kampf, S Wang, N Yehya, A Van Nas, ... Journal of biology 6, 1-15, 2007 | 382 | 2007 |
| Validation of candidate causal genes for obesity that affect shared metabolic pathways and networks X Yang, JL Deignan, H Qi, J Zhu, S Qian, J Zhong, G Torosyan, S Majid, ... Nature genetics 41 (4), 415-423, 2009 | 332 | 2009 |
| Systematic genetic and genomic analysis of cytochrome P450 enzyme activities in human liver X Yang, B Zhang, C Molony, E Chudin, K Hao, J Zhu, A Gaedigk, C Suver, ... Genome research 20 (8), 1020-1036, 2010 | 327 | 2010 |
| Extended multiplexing of tandem mass tags (TMT) labeling reveals age and high fat diet specific proteome changes in mouse epididymal adipose tissue DL Plubell, PA Wilmarth, Y Zhao, AM Fenton, J Minnier, AP Reddy, ... Molecular & Cellular Proteomics 16 (5), 873-890, 2017 | 320 | 2017 |
| Integrating pathway analysis and genetics of gene expression for genome-wide association studies H Zhong, X Yang, LM Kaplan, C Molony, EE Schadt The American Journal of Human Genetics 86 (4), 581-591, 2010 | 292 | 2010 |
| Targeting BCAA catabolism to treat obesity-associated insulin resistance M Zhou, J Shao, CY Wu, L Shu, W Dong, Y Liu, M Chen, RM Wynn, ... Diabetes 68 (9), 1730-1746, 2019 | 277 | 2019 |
| Sherlock: detecting gene-disease associations by matching patterns of expression QTL and GWAS X He, CK Fuller, Y Song, Q Meng, B Zhang, X Yang, H Li The American Journal of Human Genetics 92 (5), 667-680, 2013 | 276 | 2013 |
| Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease VP Mäkinen, M Civelek, Q Meng, B Zhang, J Zhu, C Levian, T Huan, ... PLoS genetics 10 (7), e1004502, 2014 | 235* | 2014 |
| Applications and limitations of mouse models for understanding human atherosclerosis M Von Scheidt, Y Zhao, Z Kurt, C Pan, L Zeng, X Yang, H Schunkert, ... Cell metabolism 25 (2), 248-261, 2017 | 234 | 2017 |
| Liver and adipose expression associated SNPs are enriched for association to type 2 diabetes H Zhong, J Beaulaurier, PY Lum, C Molony, X Yang, DJ MacNeil, ... PLoS genetics 6 (5), e1000932, 2010 | 206 | 2010 |
| Common dysregulation network in the human prefrontal cortex underlies two neurodegenerative diseases M Narayanan, JL Huynh, K Wang, X Yang, S Yoo, J McElwee, B Zhang, ... Molecular systems biology 10 (7), 743, 2014 | 194 | 2014 |
| A systems biology framework identifies molecular underpinnings of coronary heart disease T Huan, B Zhang, Z Wang, R Joehanes, J Zhu, AD Johnson, S Ying, ... Arteriosclerosis, thrombosis, and vascular biology 33 (6), 1427-1434, 2013 | 181* | 2013 |
| Single cell molecular alterations reveal target cells and pathways of concussive brain injury D Arneson, G Zhang, Z Ying, Y Zhuang, HR Byun, IS Ahn, ... Nature communications 9 (1), 3894, 2018 | 165 | 2018 |
Eric SchadtProfessor of Genetics and Genomic Sciences, Mount Sinai School of MedicineVerified email at mssm.edu