Sanne Smeekens

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Cisca Wijmenga, PhDERC advanced investigator; Professor of Human Genetics, Dept Genetics (MGE), UMCG, Groningen, theVerified email at umcg.nl
Mark GresnigtJunior Research Group Adaptive Pathogenicity Strategies, Hans Knöll Institut, Leibniz Institute forVerified email at leibniz-hki.de
Shih-Chin James ChengXiamen University, School of Life ScienceVerified email at xmu.edu.cn
Lude FrankeProfessor of Functional Genomics, University Medical Centre GroningenVerified email at cleverfranke.com
Sebo WithoffDept. of Genetics, University Medical Center Groningen, the Netherlands.Verified email at umcg.nl
I. JoostenRadboud University Medical Centre, Nijmegen, The NetherlandsVerified email at radboudumc.nl
Curtis HuttenhowerDepartment of Biostatistics, Harvard School of Public HealthVerified email at hsph.harvard.edu
Jakob BegunAssociate Professor, University of QueenslandVerified email at mater.uq.edu.au
Joris VeltmanInstitute of Genetics & Cancer, University of Edinburgh, United KingdomVerified email at ed.ac.uk
Esther van de VosseAssistant Professor, Leiden University Medical Center, Leiden, The NetherlandsVerified email at LUMC.nl
Luigina RomaniProfessor of General PathologyVerified email at unipg.it
William K. ScottProfessor of Human Genetics, University of MiamiVerified email at med.miami.edu
Megan LenardonUniversity New South WalesVerified email at unsw.edu.au
Cleo van DiemenDept of Genetics, University Medical Center GroningenVerified email at umcg.nl
Evangelos Giamarellos-BourboulisNational and Kapodistrian University of Athens, Medical SchoolVerified email at med.uoa.gr
Matthijs KoxAssistant Professor, department of Intensive Care Medicine, Radboud University Medical CentreVerified email at radboudumc.nl
Karin FransenPhD-student of Genetics, University medical centre GroningenVerified email at umcg.nl
Suzanne van SommerenPhD studentVerified email at umcg.nl
Peter ArkwrightUniversity of ManchesterVerified email at manchester.ac.uk
Adilia WarrisMRC Centre for Medical Mycology, University of ExeterVerified email at exeter.ac.uk

Sanne Smeekens

Clinical Laboratory Geneticist

Verified email at radboudumc.nl


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Linking the human gut microbiome to inflammatory cytokine production capacity M Schirmer, SP Smeekens, H Vlamakis, M Jaeger, M Oosting, ... Cell 167 (4), 1125-1136. e8, 2016	1170	2016
The effect of host genetics on the gut microbiome MJ Bonder, A Kurilshikov, EF Tigchelaar, Z Mujagic, F Imhann, AV Vila, ... Nature genetics 48 (11), 1407-1412, 2016	831	2016
STAT1 Mutations in Autosomal Dominant Chronic Mucocutaneous Candidiasis FL van de Veerdonk, TS Plantinga, A Hoischen, SP Smeekens, ... New England Journal of Medicine 365 (1), 54-61, 2011	747	2011
Host and environmental factors influencing individual human cytokine responses R Ter Horst, M Jaeger, SP Smeekens, M Oosting, MA Swertz, Y Li, ... Cell 167 (4), 1111-1124. e13, 2016	508	2016
A functional genomics approach to understand variation in cytokine production in humans Y Li, M Oosting, SP Smeekens, M Jaeger, R Aguirre-Gamboa, KTT Le, ... Cell 167 (4), 1099-1110. e14, 2016	343	2016
Gut microbiome in ADHD and its relation to neural reward anticipation E Aarts, THA Ederveen, J Naaijen, MP Zwiers, J Boekhorst, ... PloS one 12 (9), e0183509, 2017	329	2017
IL-1 receptor blockade restores autophagy and reduces inflammation in chronic granulomatous disease in mice and in humans A de Luca, SP Smeekens, A Casagrande, R Iannitti, KL Conway, ... Proceedings of the National Academy of Sciences 111 (9), 3526-3531, 2014	317	2014
Reactive oxygen species–independent activation of the IL-1β inflammasome in cells from patients with chronic granulomatous disease FL van de Veerdonk, SP Smeekens, LAB Joosten, BJ Kullberg, ... Proceedings of the National Academy of Sciences 107 (7), 3030-3033, 2010	270	2010
The dectin-1/inflammasome pathway is responsible for the induction of protective T-helper 17 responses that discriminate between yeasts and hyphae of Candida albicans SC Cheng, FL van de Veerdonk, M Lenardon, M Stoffels, T Plantinga, ... Journal of leukocyte biology 90 (2), 357-366, 2011	222	2011
Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans SP Smeekens, A Ng, V Kumar, MD Johnson, TS Plantinga, C Van Diemen, ... Nature communications 4 (1), 1342, 2013	211	2013
Inter-individual variability and genetic influences on cytokine responses to bacteria and fungi Y Li, M Oosting, P Deelen, I Ricano-Ponce, S Smeekens, M Jaeger, ... Nature medicine 22 (8), 952-960, 2016	200	2016
Differential effects of environmental and genetic factors on T and B cell immune traits R Aguirre-Gamboa, I Joosten, PCM Urbano, RG van der Molen, ... Cell reports 17 (9), 2474-2487, 2016	196	2016
The inflammasome drives protective Th1 and Th17 cellular responses in disseminated candidiasis FL van de Veerdonk, LAB Joosten, PJ Shaw, SP Smeekens, ... European journal of immunology 41 (8), 2260-2268, 2011	160	2011
Genetic susceptibility to Candida infections SP Smeekens, FL van de Veerdonk, BJ Kullberg, MG Netea EMBO molecular medicine 5 (6), 805-813, 2013	158	2013
Gain‐of‐function STAT1 mutations impair STAT3 activity in patients with chronic mucocutaneous candidiasis (CMC) J Zheng, FL van de Veerdonk, KL Crossland, SP Smeekens, CM Chan, ... European journal of immunology 45 (10), 2834-2846, 2015	136	2015
Integration of multi-omics data and deep phenotyping enables prediction of cytokine responses OB Bakker, R Aguirre-Gamboa, S Sanna, M Oosting, SP Smeekens, ... Nature immunology 19 (7), 776-786, 2018	132	2018
STAT1 hyperphosphorylation and defective IL12R/IL23R signaling underlie defective immunity in autosomal dominant chronic mucocutaneous candidiasis SP Smeekens, TS Plantinga, FL van de Veerdonk, B Heinhuis, ... PloS one 6 (12), e29248, 2011	131	2011
Sex-specific regulation of inflammation and metabolic syndrome in obesity R Ter Horst, ICL van den Munckhof, K Schraa, R Aguirre-Gamboa, ... Arteriosclerosis, thrombosis, and vascular biology 40 (7), 1787-1800, 2020	124	2020
Candida albicans dampens host defense by downregulating IL-17 production SC Cheng, F van de Veerdonk, S Smeekens, LAB Joosten, ... The Journal of Immunology 185 (4), 2450-2457, 2010	112	2010
Joosten LAB, Zhernakova A, Huttenhower C, Wijmenga C, Netea MG, Xavier RJ. Linking the human gut microbiome to inflammatory cytokine production capacity M Schirmer, SP Smeekens, H Vlamakis, M Jaeger, M Oosting, ... Cell 167 (4), 1125-1136, 2016	110	2016

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