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Joshua Keefe
Joshua Keefe
Verified email at bcm.edu
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Year
Genome‐wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease
C Yao, G Chen, C Song, J Keefe, M Mendelson, T Huan, BB Sun, A Laser, ...
Nature communications 9 (1), 3268, 2018
3722018
Genome-wide identification of DNA methylation QTLs in whole blood highlights pathways for cardiovascular disease
T Huan, R Joehanes, CI Song, F Peng, Y Guo, M Mendelson, C Yao, ...
Nature communications 10 (1), 4267, 2019
1942019
Multigenerational memory and adaptive adhesion in early bacterial biofilm communities
CK Lee, J De Anda, AE Baker, RR Bennett, Y Luo, EY Lee, JA Keefe, ...
Proceedings of the National Academy of Sciences 115 (17), 4471-4476, 2018
1872018
Lipidomic profiling identifies signatures of metabolic risk
X Yin, CM Willinger, J Keefe, J Liu, A Fernández-Ortiz, B Ibáñez, ...
EBioMedicine 51, 2020
782020
Role of Ca2+ in healthy and pathologic cardiac function: from normal excitation–contraction coupling to mutations that cause inherited arrhythmia
JA Keefe, OM Moore, KS Ho, XHT Wehrens
Archives of toxicology 97 (1), 73-92, 2023
292023
Hydrogel platform for aqueous two-phase concentration of a target to enhance its detection
DT Kamei, BM Wu, DY Pereira, CM Wu, MF Yee, JA Keefe, CC Pearce, ...
US Patent 11,327,075, 2022
292022
Epigenome-wide association study of DNA methylation and microRNA expression highlights novel pathways for human complex traits
T Huan, M Mendelson, R Joehanes, C Yao, C Liu, C Song, ...
Epigenetics 15 (1-2), 183-198, 2020
262020
Chronic kidney disease promotes atrial fibrillation via inflammasome pathway activation
J Song, JA Navarro-Garcia, J Wu, A Saljic, I Abu-Taha, L Li, SK Lahiri, ...
The Journal of Clinical Investigation 133 (19), 2023
242023
Evidence for a Causal Role of the SH2B32M Axis in Blood Pressure Regulation: Framingham Heart Study
JA Keefe, SJ Hwang, T Huan, M Mendelson, C Yao, P Courchesne, ...
Hypertension 73 (2), 497-503, 2019
232019
Cardiac function, structural, and electrical remodeling by microgravity exposure
MR Sy, JA Keefe, JP Sutton, XHT Wehrens
American Journal of Physiology-Heart and Circulatory Physiology 324 (1), H1-H13, 2023
192023
An integrative genomic strategy identifies sRAGE as a causal and protective biomarker of lung function
J Keefe, C Yao, SJ Hwang, P Courchesne, GY Lee, J Dupuis, JP Mizgerd, ...
Chest 161 (1), 76-84, 2022
82022
Mouse models of spontaneous atrial fibrillation
JA Keefe, MM Hulsurkar, S Reilly, XHT Wehrens
Mammalian Genome 34 (2), 298-311, 2023
72023
Abnormalities in cardiac and inflammatory biomarkers in ambulatory subjects after COVID-19 infection
JA Keefe, V Avadhanula, EG Nicholson, S Devaraj, PA Piedra, B Bozkurt, ...
IJC Heart & Vasculature 43, 101144, 2022
72022
Integrative genomic analysis reveals four protein biomarkers for platelet traits
DH Lee, C Yao, A Bhan, T Schlaeger, J Keefe, BAT Rodriguez, SJ Hwang, ...
Circulation research 127 (9), 1182-1194, 2020
72020
Tachycardia and atrial fibrillation-related cardiomyopathies: potential mechanisms and current therapies
JA Keefe, R Garber, MD McCauley, XHT Wehrens
Heart Failure 12 (4), 605-615, 2024
62024
Author Correction: Genome‐wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease
C Yao, G Chen, C Song, J Keefe, M Mendelson, T Huan, BB Sun, A Laser, ...
Nature Communications 9, 2018
62018
In-depth characterization of a mouse model of postoperative atrial fibrillation
JA Keefe, JA Navarro-Garcia, L Ni, S Reilly, D Dobrev, XHT Wehrens
The journal of cardiovascular aging 2, 2022
42022
Long-term efficacy and safety of cardiac genome editing for catecholaminergic polymorphic ventricular tachycardia
OM Moore, Y Aguilar-Sanchez, SK Lahiri, MM Hulsurkar, ...
The Journal of Cardiovascular Aging 4 (1), N/A-N/A, 2024
12024
Integrative genomic analysis and functional studies reveal GP5, GRN, MPO and MCAM as causal protein biomarkers for platelet traits
DH Lee, C Yao, A Bhan, T Schlaeger, J Keefe, BAT Rodriguez, SJ Hwang, ...
Biorxiv, 854216, 2019
12019
Interrogating the Proteome to Elucidate Putatively Causal Biomarkers of Emphysema: The Framingham Heart Study
J Keefe, C Yao, SJ Hwang, P Courchesne, G O’Connor, J Dupuis, D Levy
Circulation 138 (Suppl_1), A16070-A16070, 2018
12018
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