Thioredoxin reductase: A target for gold compounds acting as potential anticancer drugs A Bindoli, MP Rigobello, G Scutari, C Gabbiani, A Casini, L Messori Coordination Chemistry Reviews 253 (11-12), 1692-1707, 2009 | 683 | 2009 |
Inhibition of thioredoxin reductase by auranofin induces apoptosis in cisplatin-resistant human ovarian cancer cells C Marzano, V Gandin, A Folda, G Scutari, A Bindoli, MP Rigobello Free Radical Biology and Medicine 42 (6), 872-881, 2007 | 498 | 2007 |
Biochemical and toxicological properties of the oxidation products of catecholamines A Bindoli, MP Rigobello, DJ Deeble Free Radical Biology and Medicine 13 (4), 391-405, 1992 | 379 | 1992 |
Emerging protein targets for anticancer metallodrugs: inhibition of thioredoxin reductase and cathepsin B by antitumor ruthenium (II)− arene compounds A Casini, C Gabbiani, F Sorrentino, MP Rigobello, A Bindoli, TJ Geldbach, ... Journal of medicinal chemistry 51 (21), 6773-6781, 2008 | 349 | 2008 |
European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS) J Egea, I Fabregat, YM Frapart, P Ghezzi, A Görlach, T Kietzmann, ... Redox biology 13, 94-162, 2017 | 337 | 2017 |
Cancer cell death induced by phosphine gold (I) compounds targeting thioredoxin reductase V Gandin, AP Fernandes, MP Rigobello, B Dani, F Sorrentino, F Tisato, ... Biochemical pharmacology 79 (2), 90-101, 2010 | 309 | 2010 |
Gold(I) Carbene Complexes Causing Thioredoxin 1 and Thioredoxin 2 Oxidation as Potential Anticancer Agents E Schuh, C Pflüger, A Citta, A Folda, MP Rigobello, A Bindoli, A Casini, ... Journal of medicinal chemistry 55 (11), 5518-5528, 2012 | 269 | 2012 |
Gold complexes inhibit mitochondrial thioredoxin reductase: consequences on mitochondrial functions MP Rigobello, L Messori, G Marcon, MA Cinellu, M Bragadin, A Folda, ... Journal of inorganic biochemistry 98 (10), 1634-1641, 2004 | 252 | 2004 |
Induction of mitochondrial permeability transition by auranofin, a gold (I)-phosphine derivative MP Rigobello, G Scutari, R Boscolo, A Bindoli British journal of pharmacology 136 (8), 1162, 2002 | 239 | 2002 |
Principles in redox signaling: from chemistry to functional significance A Bindoli, MP Rigobello Antioxidants & redox signaling 18 (13), 1557-1593, 2013 | 215 | 2013 |
Mitochondrial thioredoxin reductase inhibition by gold (I) compounds and concurrent stimulation of permeability transition and release of cytochrome c MP Rigobello, G Scutari, A Folda, A Bindoli Biochemical pharmacology 67 (4), 689-696, 2004 | 180 | 2004 |
Gold (III)-dithiocarbamato complexes induce cancer cell death triggered by thioredoxin redox system inhibition and activation of ERK pathway D Saggioro, MP Rigobello, L Paloschi, A Folda, SA Moggach, S Parsons, ... Chemistry & biology 14 (10), 1128-1139, 2007 | 176 | 2007 |
Purification of mitochondrial thioredoxin reductase and its involvement in the redox regulation of membrane permeability MP Rigobello, MT Callegaro, E Barzon, M Benetti, A Bindoli Free Radical Biology and Medicine 24 (2), 370-376, 1998 | 174 | 1998 |
Milk-derived bioactive peptides exhibit antioxidant activity through the Keap1-Nrf2 signaling pathway F Tonolo, A Folda, L Cesaro, V Scalcon, O Marin, S Ferro, A Bindoli, ... Journal of Functional Foods 64, 103696, 2020 | 158 | 2020 |
Fluorescent silver(i) and gold(i)–N-heterocyclic carbene complexes with cytotoxic properties: mechanistic insights A Citta, E Schuh, F Mohr, A Folda, ML Massimino, A Bindoli, A Casini, ... Metallomics 5 (8), 1006-1015, 2013 | 151 | 2013 |
In vitro antitumour activity of water soluble Cu (I), Ag (I) and Au (I) complexes supported by hydrophilic alkyl phosphine ligands C Santini, M Pellei, G Papini, B Morresi, R Galassi, S Ricci, F Tisato, ... Journal of Inorganic Biochemistry 105 (2), 232-240, 2011 | 141 | 2011 |
Anticancer therapeutics that target selenoenzymes: synthesis, characterization, in vitro cytotoxicity, and thioredoxin reductase inhibition of a series of gold (I) complexes … E Vergara, A Casini, F Sorrentino, O Zava, E Cerrada, MP Rigobello, ... ChemMedChem: Chemistry Enabling Drug Discovery 5 (1), 96-102, 2010 | 140 | 2010 |
The mitochondrial antioxidant defence system and its response to oxidative stress T Rabilloud, M Heller, MP Rigobello, A Bindoli, R Aebersold, J Lunardi PROTEOMICS: International Edition 1 (9), 1105-1110, 2001 | 134 | 2001 |
Significance of the mitochondrial thioredoxin reductase in cancer cells: An update on role, targets and inhibitors V Scalcon, A Bindoli, MP Rigobello Free Radical Biology and Medicine 127, 62-79, 2018 | 125 | 2018 |
Effect of auranofin on the mitochondrial generation of hydrogen peroxide. Role of thioredoxin reductase MP Rigobello, A Folda, MC Baldoin, G Scutari, A Bindoli Free radical research 39 (7), 687-695, 2005 | 124 | 2005 |