Cutting edge: autoimmune disease risk variant of STAT4 confers increased sensitivity to IFN-α in lupus patients in vivo SN Kariuki, KA Kirou, EJ MacDermott, L Barillas-Arias, MK Crow, ... The Journal of Immunology 182 (1), 34-38, 2009 | 303 | 2009 |
Autoimmune disease risk variant of IFIH1 is associated with increased sensitivity to IFN-α and serologic autoimmunity in lupus patients T Robinson, SN Kariuki, BS Franek, M Kumabe, AA Kumar, M Badaracco, ... The Journal of Immunology 187 (3), 1298-1303, 2011 | 173 | 2011 |
Genetic variation at the IRF7/PHRF1 locus is associated with autoantibody profile and serum interferon‐α activity in lupus patients R Salloum, BS Franek, SN Kariuki, L Rhee, RA Mikolaitis, M Jolly, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2010 | 166 | 2010 |
IRF5 haplotypes demonstrate diverse serological associations which predict serum interferon alpha activity and explain the majority of the genetic association with systemic … TB Niewold, JA Kelly, SN Kariuki, BS Franek, AA Kumar, KM Kaufman, ... Annals of the rheumatic diseases 71 (3), 463-469, 2012 | 162 | 2012 |
Human genetics and malaria resistance SN Kariuki, TN Williams Human genetics 139 (6), 801-811, 2020 | 152 | 2020 |
Elevated serum interferon‐α activity in juvenile dermatomyositis: associations with disease activity at diagnosis and after thirty‐six months of therapy TB Niewold, SN Kariuki, GA Morgan, S Shrestha, LM Pachman Arthritis & Rheumatism: Official Journal of the American College of …, 2009 | 141 | 2009 |
Age-and gender-specific modulation of serum osteopontin and interferon-α by osteopontin genotype in systemic lupus erythematosus SN Kariuki, JG Moore, KA Kirou, MK Crow, TO Utset, TB Niewold Genes & Immunity 10 (5), 487-494, 2009 | 125 | 2009 |
Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study CM Ndila, S Uyoga, AW Macharia, G Nyutu, N Peshu, J Ojal, M Shebe, ... The Lancet Haematology 5 (8), e333-e345, 2018 | 123 | 2018 |
Trait-stratified genome-wide association study identifies novel and diverse genetic associations with serologic and cytokine phenotypes in systemic lupus erythematosus SN Kariuki, BS Franek, AA Kumar, J Arrington, RA Mikolaitis, TO Utset, ... Arthritis research & therapy 12, 1-12, 2010 | 115 | 2010 |
African-derived genetic polymorphisms in TNFAIP3 mediate risk for autoimmunity JP Lodolce, LE Kolodziej, L Rhee, SN Kariuki, BS Franek, NM McGreal, ... The Journal of Immunology 184 (12), 7001-7009, 2010 | 107 | 2010 |
The PTPN22 C1858T polymorphism is associated with skewing of cytokine profiles toward high interferon‐α activity and low tumor necrosis factor α levels in … SN Kariuki, MK Crow, TB Niewold Arthritis & Rheumatism 58 (9), 2818-2823, 2008 | 102 | 2008 |
Red blood cell tension protects against severe malaria in the Dantu blood group SN Kariuki, A Marin-Menendez, V Introini, BJ Ravenhill, YC Lin, ... Nature 585 (7826), 579-583, 2020 | 98 | 2020 |
Genetic regulation of serum cytokines in systemic lupus erythematosus SN Kariuki, TB Niewold Translational Research 155 (3), 109-117, 2010 | 81 | 2010 |
Genetic analysis of the pathogenic molecular sub-phenotype interferon-alpha identifies multiple novel loci involved in systemic lupus erythematosus SN Kariuki, Y Ghodke-Puranik, JM Dorschner, BS Chrabot, JA Kelly, ... Genes & Immunity 16 (1), 15-23, 2015 | 74 | 2015 |
Genetic variation near IRF8 is associated with serologic and cytokine profiles in systemic lupus erythematosus and multiple sclerosis BS Chrabot, SN Kariuki, MI Zervou, X Feng, J Arrington, M Jolly, ... Genes & Immunity 14 (8), 471-478, 2013 | 61 | 2013 |
Brief Report: IRF5 systemic lupus erythematosus risk haplotype is associated with asymptomatic serologic autoimmunity and progression to clinical autoimmunity in mothers of … TS Cherian, SN Kariuki, BS Franek, JP Buyon, RM Clancy, TB Niewold Arthritis & Rheumatism 64 (10), 3383-3387, 2012 | 40 | 2012 |
Gene-gene-sex interaction in cytokine gene polymorphisms revealed by serum interferon alpha phenotype in juvenile dermatomyositis TB Niewold, SN Kariuki, GA Morgan, S Shrestha, LM Pachman The Journal of pediatrics 157 (4), 653-657, 2010 | 39 | 2010 |
Osteopontin alleles are associated with clinical characteristics in systemic lupus erythematosus T Trivedi, BS Franek, SL Green, SN Kariuki, M Kumabe, RA Mikolaitis, ... BioMed Research International 2011 (1), 802581, 2011 | 38 | 2011 |
Linkage of type I interferon activity and TNF-alpha levels in serum with sarcoidosis manifestations and ancestry NJ Sweiss, W Zhang, BS Franek, SN Kariuki, DR Moller, KC Patterson, ... PLoS One 6 (12), e29126, 2011 | 34 | 2011 |
Promoter Variant of PIK3C3 Is Associated with Autoimmunity against Ro and Sm Epitopes in African‐American Lupus Patients SN Kariuki, BS Franek, RA Mikolaitis, TO Utset, M Jolly, AD Skol, ... BioMed Research International 2010 (1), 826434, 2010 | 32 | 2010 |