Zoonotic origins of human coronaviruses ZW Ye, S Yuan, KS Yuen, SY Fung, CP Chan, DY Jin International journal of biological sciences 16 (10), 1686, 2020 | 1232 | 2020 |
SARS-CoV-2 and COVID-19: The most important research questions KS Yuen, ZW Ye, SY Fung, CP Chan, DY Jin Cell & bioscience 10, 1-5, 2020 | 883 | 2020 |
Severe acute respiratory syndrome coronavirus ORF3a protein activates the NLRP3 inflammasome by promoting TRAF3-dependent ubiquitination of ASC KL Siu, KS Yuen, C Castaño-Rodriguez, ZW Ye, ML Yeung, SY Fung, ... The FASEB Journal 33 (8), 8865, 2019 | 561 | 2019 |
A tug-of-war between severe acute respiratory syndrome coronavirus 2 and host antiviral defence: lessons from other pathogenic viruses SY Fung, KS Yuen, ZW Ye, CP Chan, DY Jin Emerging microbes & infections 9 (1), 558-570, 2020 | 495 | 2020 |
SREBP-dependent lipidomic reprogramming as a broad-spectrum antiviral target S Yuan, H Chu, JFW Chan, ZW Ye, L Wen, B Yan, PM Lai, KM Tee, ... Nature communications 10 (1), 120, 2019 | 248 | 2019 |
Clofazimine broadly inhibits coronaviruses including SARS-CoV-2 S Yuan, X Yin, X Meng, JFW Chan, ZW Ye, L Riva, L Pache, CCY Chan, ... Nature 593 (7859), 418-423, 2021 | 201 | 2021 |
Metallodrug ranitidine bismuth citrate suppresses SARS-CoV-2 replication and relieves virus-associated pneumonia in Syrian hamsters S Yuan, R Wang, JFW Chan, AJ Zhang, T Cheng, KKH Chik, ZW Ye, ... Nature microbiology 5 (11), 1439-1448, 2020 | 183 | 2020 |
Pathogenicity, transmissibility, and fitness of SARS-CoV-2 Omicron in Syrian hamsters S Yuan, ZW Ye, R Liang, K Tang, AJ Zhang, G Lu, CP Ong, VK Man Poon, ... Science 377 (6604), 428-433, 2022 | 168 | 2022 |
Inhibition of AIM 2 inflammasome activation by a novel transcript isoform of IFI 16 PH Wang, ZW Ye, JJ Deng, KL Siu, WW Gao, V Chaudhary, Y Cheng, ... EMBO reports 19 (10), e45737, 2018 | 92 | 2018 |
Discovery of the FDA-approved drugs bexarotene, cetilistat, diiodohydroxyquinoline, and abiraterone as potential COVID-19 treatments with a robust two-tier screening system S Yuan, JFW Chan, KKH Chik, CCY Chan, JOL Tsang, R Liang, J Cao, ... Pharmacological research 159, 104960, 2020 | 79 | 2020 |
Broad-spectrum host-based antivirals targeting the interferon and lipogenesis pathways as potential treatment options for the pandemic coronavirus disease 2019 (COVID-19) S Yuan, CCY Chan, KKH Chik, JOL Tsang, R Liang, J Cao, K Tang, ... Viruses 12 (6), 628, 2020 | 63 | 2020 |
Viruses harness YxxØ motif to interact with host AP2M1 for replication: A vulnerable broad-spectrum antiviral target S Yuan, H Chu, J Huang, X Zhao, ZW Ye, PM Lai, L Wen, JP Cai, Y Mo, ... Science advances 6 (35), eaba7910, 2020 | 60 | 2020 |
Beneficial effect of combinational methylprednisolone and remdesivir in hamster model of SARS-CoV-2 infection ZW Ye, S Yuan, JFW Chan, AJ Zhang, CY Yu, CP Ong, D Yang, ... Emerging microbes & infections 10 (1), 291-304, 2021 | 58 | 2021 |
The Arabidopsis cytosolic acyl-CoA-binding proteins play combinatory roles in pollen development AS Hsiao, EC Yeung, ZW Ye, ML Chye Plant and Cell Physiology 56 (2), 322-333, 2015 | 55 | 2015 |
Antibody-dependent cell-mediated cytotoxicity epitopes on the hemagglutinin head region of pandemic H1N1 influenza virus play detrimental roles in H1N1-infected mice ZW Ye, S Yuan, KM Poon, L Wen, D Yang, Z Sun, C Li, M Hu, H Shuai, ... Frontiers in immunology 8, 317, 2017 | 47 | 2017 |
Middle East respiratory syndrome coronavirus ORF8b accessory protein suppresses type I IFN expression by impeding HSP70-dependent activation of IRF3 kinase IKKε LYR Wong, ZW Ye, PY Lui, X Zheng, S Yuan, L Zhu, SY Fung, KS Yuen, ... The Journal of Immunology 205 (6), 1564-1579, 2020 | 45 | 2020 |
SARS-CoV-2 exploits host DGAT and ADRP for efficient replication S Yuan, B Yan, J Cao, ZW Ye, R Liang, K Tang, C Luo, J Cai, H Chu, ... Cell Discovery 7 (1), 100, 2021 | 42 | 2021 |
PB1-F2 protein of highly pathogenic influenza A (H7N9) virus selectively suppresses RNA-induced NLRP3 inflammasome activation through inhibition of MAVS-NLRP3 interaction PHH Cheung, ZW Ye, TWT Lee, H Chen, CP Chan, DY Jin Journal of Leucocyte Biology 108 (5), 1655-1663, 2020 | 41 | 2020 |
Diagnosis, treatment, control and prevention of SARS-CoV-2 and coronavirus disease 2019: back to the future ZW Ye, DY Jin Sheng wu gong cheng xue bao= Chinese journal of biotechnology 36 (4), 571-592, 2020 | 41 | 2020 |
Targeting papain-like protease for broad-spectrum coronavirus inhibition S Yuan, X Gao, K Tang, JP Cai, M Hu, P Luo, L Wen, ZW Ye, C Luo, ... Protein & Cell 13 (12), 940-953, 2022 | 40 | 2022 |