| BET bromodomain inhibitors MP Schwalm, S Knapp Current opinion in chemical biology 68, 102148, 2022 | 70 | 2022 |
| PROTAC degraders as chemical probes for studying target biology and target validation V Němec, MP Schwalm, S Müller, S Knapp Chemical Society Reviews 51 (18), 7971-7993, 2022 | 51 | 2022 |
| Tracking the PROTAC degradation pathway in living cells highlights the importance of ternary complex measurement for PROTAC optimization MP Schwalm, A Krämer, A Dölle, J Weckesser, X Yu, J Jin, K Saxena, ... Cell chemical biology 30 (7), 753-765. e8, 2023 | 38 | 2023 |
| Development of the first covalent monopolar spindle kinase 1 (MPS1/TTK) Inhibitor RA M. Serafim, A da Silva Santiago, MP Schwalm, Z Hu, CV Dos Reis, ... Journal of Medicinal Chemistry 65 (4), 3173-3192, 2022 | 21 | 2022 |
| Discovery of a potent and highly isoform-selective inhibitor of the neglected ribosomal protein S6 kinase beta 2 (S6K2) S Gerstenecker, L Haarer, M Schröder, M Kudolo, MP Schwalm, V Wydra, ... Cancers 13 (20), 5133, 2021 | 16 | 2021 |
| A Toolbox for the Generation of Chemical Probes for Baculovirus IAP Repeat Containing Proteins MP Schwalm, L Berger, M Meuter, J Vasta, C Corona, S Röhm, B Berger, ... Frontiers in cell and developmental biology 10, 2022 | 15 | 2022 |
| A chemical probe to modulate human GID4 Pro/N-degron interactions DDG Owens, MER Maitland, A Khalili Yazdi, X Song, V Reber, ... Nature Chemical Biology, 1-12, 2024 | 12 | 2024 |
| Crystal structure and inhibitor identifications reveal targeting opportunity for the atypical MAPK kinase ERK3 M Schröder, P Filippakopoulos, MP Schwalm, CA Ferrer, DH Drewry, ... International journal of molecular sciences 21 (21), 7953, 2020 | 12 | 2020 |
| Development of novel urea-based ATM kinase inhibitors with subnanomolar cellular potency and high kinome selectivity T Dimitrov, C Anli, AA Moschopoulou, T Kronenberger, M Kudolo, ... European Journal of Medicinal Chemistry 235, 114234, 2022 | 9 | 2022 |
| Expanding the ligand spaces for E3 ligases for the design of protein degraders RSZ Saleem, MP Schwalm, S Knapp Bioorganic & medicinal chemistry, 117718, 2024 | 8 | 2024 |
| Development of Highly Potent and Selective Covalent FGFR4 Inhibitors Based on SNAr Electrophiles M Schwarz, M Kurkunov, F Wittlinger, R Rudalska, G Wang, MP Schwalm, ... Journal of medicinal chemistry 67 (8), 6549-6569, 2024 | 7 | 2024 |
| Development of potent dual BET/HDAC inhibitors via pharmacophore merging and structure-guided optimization N Bauer, DI Balourdas, JR Schneider, X Zhang, LM Berger, BT Berger, ... ACS chemical biology 19 (2), 266-279, 2024 | 7 | 2024 |
| Luciferase-and HaloTag-based reporter assays to measure small-molecule-induced degradation pathway in living cells MP Schwalm, K Saxena, S Müller, S Knapp Nature Protocols, 1-41, 2024 | 6 | 2024 |
| Toward effective Atg8‐based ATTECs: Approaches and perspectives MP Schwalm, S Knapp, VV Rogov Journal of Cellular Biochemistry 125 (11), e30380, 2024 | 5 | 2024 |
| Thalidomide derivatives degrade BCL-2 by reprogramming the binding surface of CRBN J Wang, M Heinz, K Han, VJ Shah, S Hasselbeck, MP Schwalm, ... Cell Reports Physical Science 5 (5), 2024 | 3 | 2024 |
| Targeting LC3/GABARAP for degrader development and autophagy modulation MP Schwalm, J Dopfer, A Kumar, FA Greco, N Bauer, F Löhr, J Heering, ... bioRxiv, 2023.10. 05.560930, 2023 | 3 | 2023 |
| High-Throughput Screening for LC3/GABARAP Binders Utilizing the Fluorescence Polarization Assay MP Schwalm, J Dopfer, S Knapp, VV Rogov Selective Autophagy: Methods and Protocols, 203-218, 2024 | 2 | 2024 |
| Inhibitor-induced supercharging of kinase turnover via endogenous proteolytic circuits NS Scholes, M Bertoni, A Comajuncosa-Creus, K Kladnik, F Frommelt, ... bioRxiv, 2024.07. 10.602881, 2024 | 2 | 2024 |
| tracerDB: a crowdsourced fluorescent tracer database for target engagement analysis J Dopfer, JD Vasta, S Müller, S Knapp, MB Robers, MP Schwalm Nature Communications 15 (1), 5646, 2024 | 2 | 2024 |
| Splice variants of CK1α and CK1α-like: Comparative analysis of subcellular localization, kinase activity and function in the Wnt signaling pathway T Gybeľ, Š Čada, D Klementová, MP Schwalm, BT Berger, M Šebesta, ... Journal of Biological Chemistry, 107407, 2024 | 2 | 2024 |
Stefan KnappUniversity of FrankfurtVerified email at pharmchem.uni-frankfurt.de