| Glutaredoxins: glutathione-dependent redox enzymes with functions far beyond a simple thioredoxin backup system AP Fernandes, A Holmgren Antioxidants and Redox Signaling 6 (1), 63-74, 2004 | 876 | 2004 |
| Selenium compounds as therapeutic agents in cancer AP Fernandes, V Gandin Biochimica et Biophysica Acta (BBA)-General Subjects 1850 (8), 1642-1660, 2015 | 488 | 2015 |
| Organic selenium compounds as potential chemotherapeutic agents for improved cancer treatment V Gandin, P Khalkar, J Braude, AP Fernandes Free Radical Biology and Medicine 127, 80-97, 2018 | 320 | 2018 |
| Cancer cell death induced by phosphine gold (I) compounds targeting thioredoxin reductase V Gandin, AP Fernandes, MP Rigobello, B Dani, F Sorrentino, F Tisato, ... Biochemical pharmacology 79 (2), 90-101, 2010 | 312 | 2010 |
| Selenium and the selenoprotein thioredoxin reductase in the prevention, treatment and diagnostics of cancer M Selenius, AK Rundlöf, E Olm, AP Fernandes, M Björnstedt Antioxidants & redox signaling 12 (7), 867-880, 2010 | 205 | 2010 |
| Overexpression of glutaredoxin 2 attenuates apoptosis by preventing cytochrome c release M Enoksson, AP Fernandes, S Prast, CH Lillig, A Holmgren, S Orrenius Biochemical and biophysical research communications 327 (3), 774-779, 2005 | 201 | 2005 |
| A novel monothiol glutaredoxin (Grx4) from Escherichia coli can serve as a substrate for thioredoxin reductase AP Fernandes, M Fladvad, C Berndt, C Andrésen, CH Lillig, P Neubauer, ... Journal of Biological Chemistry 280 (26), 24544-24552, 2005 | 198 | 2005 |
| Extracellular thiol-assisted selenium uptake dependent on the xc− cystine transporter explains the cancer-specific cytotoxicity of selenite E Olm, AP Fernandes, C Hebert, AK Rundlöf, EH Larsen, O Danielsson, ... Proceedings of the National Academy of Sciences 106 (27), 11400-11405, 2009 | 196 | 2009 |
| Short interfering RNA-mediated silencing of glutaredoxin 2 increases the sensitivity of HeLa cells toward doxorubicin and phenylarsine oxide CH Lillig, ME Lönn, M Enoksson, AP Fernandes, A Holmgren Proceedings of the National Academy of Sciences 101 (36), 13227-13232, 2004 | 183 | 2004 |
| Selenite induces apoptosis in sarcomatoid malignant mesothelioma cells through oxidative stress G Nilsonne, X Sun, C Nyström, AK Rundlöf, AP Fernandes, M Björnstedt, ... Free Radical Biology and Medicine 41 (6), 874-885, 2006 | 175 | 2006 |
| Selenium induces a multi‐targeted cell death process in addition to ROS formation M Wallenberg, S Misra, AM Wasik, C Marzano, M Björnstedt, V Gandin, ... Journal of cellular and molecular medicine 18 (4), 671-684, 2014 | 143 | 2014 |
| Selenium compounds are substrates for glutaredoxins: a novel pathway for selenium metabolism and a potential mechanism for selenium-mediated cytotoxicity M Wallenberg, E Olm, C Hebert, M Björnstedt, AP Fernandes Biochemical Journal 429 (1), 85-93, 2010 | 137 | 2010 |
| Cellular and plasma levels of human glutaredoxin 1 and 2 detected by sensitive ELISA systems M Lundberg, AP Fernandes, S Kumar, A Holmgren Biochemical and biophysical research communications 319 (3), 801-809, 2004 | 113 | 2004 |
| Expression profiles of thioredoxin family proteins in human lung cancer tissue: correlation with proliferation and differentiation AP Fernandes, A Capitanio, M Selenius, O Brodin, AK Rundlöf, ... Histopathology 55 (3), 313-320, 2009 | 101 | 2009 |
| Molecular mapping of functionalities in the solution structure of reduced Grx4, a monothiol glutaredoxin from Escherichia coli M Fladvad, M Bellanda, AP Fernandes, S Mammi, A Vlamis-Gardikas, ... Journal of Biological Chemistry 280 (26), 24553-24561, 2005 | 81 | 2005 |
| Treatment of human cancer cells with selenite or tellurite in combination with auranofin enhances cell death due to redox shift MP Rigobello, V Gandin, A Folda, AK Rundlöf, AP Fernandes, A Bindoli, ... Free Radical Biology and Medicine 47 (6), 710-721, 2009 | 80 | 2009 |
| Metal-and semimetal-containing inhibitors of thioredoxin reductase as anticancer agents V Gandin, AP Fernandes Molecules 20 (7), 12732-12756, 2015 | 76 | 2015 |
| Selenium in the prevention of human cancers M Björnstedt, AP Fernandes EPMA Journal 1, 389-395, 2010 | 67 | 2010 |
| Treatment of lung cancer cells with cytotoxic levels of sodium selenite: effects on the thioredoxin system M Selenius, AP Fernandes, O Brodin, M Björnstedt, AK Rundlöf Biochemical pharmacology 75 (11), 2092-2099, 2008 | 66 | 2008 |
| Alteration of thioredoxin and glutaredoxin in the progression of Alzheimer's disease L Arodin, H Lamparter, H Karlsson, I Nennesmo, M Björnstedt, J Schröder, ... Journal of Alzheimer's Disease 39 (4), 787-797, 2014 | 65 | 2014 |
