Paracrine orchestration of intestinal tumorigenesis by a mesenchymal niche M Roulis, A Kaklamanos, M Schernthanner, P Bielecki, J Zhao, E Kaffe, ... Nature 580 (7804), 524-529, 2020 | 253 | 2020 |
Fibroblasts and myofibroblasts of the intestinal lamina propria in physiology and disease M Roulis, RA Flavell Differentiation 92 (3), 116-131, 2016 | 210 | 2016 |
Pleiotropic functions of TNF-α in the regulation of the intestinal epithelial response to inflammation M Leppkes, M Roulis, MF Neurath, G Kollias, C Becker International immunology 26 (9), 509-515, 2014 | 203 | 2014 |
Enteric nervous system-derived IL-18 orchestrates mucosal barrier immunity A Jarret, R Jackson, C Duizer, ME Healy, J Zhao, JM Rone, P Bielecki, ... Cell 180 (1), 50-63. e12, 2020 | 193 | 2020 |
Zero-preserving imputation of single-cell RNA-seq data GC Linderman, J Zhao, M Roulis, P Bielecki, RA Flavell, B Nadler, ... Nature communications 13 (1), 192, 2022 | 182 | 2022 |
Intestinal epithelial cells as producers but not targets of chronic TNF suffice to cause murine Crohn-like pathology M Roulis, M Armaka, M Manoloukos, M Apostolaki, G Kollias Proceedings of the National Academy of Sciences 108 (13), 5396-5401, 2011 | 171 | 2011 |
Role of β7 integrin and the chemokine/chemokine receptor pair CCL25/CCR9 in modeled TNF-dependent Crohn's disease M Apostolaki, M Manoloukos, M Roulis, MA Wurbel, W Müller, ... Gastroenterology 134 (7), 2025-2035, 2008 | 125 | 2008 |
Intestinal myofibroblast-specific Tpl2-Cox-2-PGE2 pathway links innate sensing to epithelial homeostasis M Roulis, C Nikolaou, E Kotsaki, E Kaffe, N Karagianni, V Koliaraki, ... Proceedings of the National Academy of Sciences 111 (43), E4658-E4667, 2014 | 104 | 2014 |
MAP3K2-regulated intestinal stromal cells define a distinct stem cell niche N Wu, H Sun, X Zhao, Y Zhang, J Tan, Y Qi, Q Wang, M Ng, Z Liu, L He, ... Nature 592 (7855), 606-610, 2021 | 84 | 2021 |
Tpl2 regulates intestinal myofibroblast HGF release to suppress colitis-associated tumorigenesis V Koliaraki, M Roulis, G Kollias The Journal of clinical investigation 122 (11), 4231-4242, 2012 | 84 | 2012 |
Host and microbiota interactions are critical for development of murine Crohn’s-like ileitis M Roulis, G Bongers, M Armaka, T Salviano, Z He, A Singh, U Seidler, ... Mucosal immunology 9 (3), 787-797, 2016 | 60 | 2016 |
m6A mRNA modification maintains colonic epithelial cell homeostasis via NF-κB–mediated antiapoptotic pathway T Zhang, C Ding, H Chen, J Zhao, Z Chen, B Chen, K Mao, Y Hao, ... Science advances 8 (12), eabl5723, 2022 | 59 | 2022 |
RNA m6A demethylase ALKBH5 regulates the development of γδ T cells C Ding, H Xu, Z Yu, M Roulis, R Qu, J Zhou, J Oh, J Crawford, Y Gao, ... Proceedings of the National Academy of Sciences 119 (33), e2203318119, 2022 | 40 | 2022 |
Humanized mouse liver reveals endothelial control of essential hepatic metabolic functions E Kaffe, M Roulis, J Zhao, R Qu, E Sefik, H Mirza, J Zhou, Y Zheng, ... Cell 186 (18), 3793-3809. e26, 2023 | 36 | 2023 |
Extensive phenotypic characterization of a new transgenic mouse reveals pleiotropic perturbations in physiology due to mesenchymal hGH minigene expression A Kaklamanos, J Rozman, M Roulis, N Karagianni, M Armaka, M Wu, ... Scientific reports 7 (1), 2397, 2017 | 3 | 2017 |
Map3k2-Regulated Intestinal Stromal Cells (MRISC) Define a Distinct Sub-cryptic Stem Cell Niche for Damage Induced Wnt Agonist R-spondin1 Production N Wu, H Sun, X Zhao, L Chen, Y Qi, Y Han, X Liu, C Gao, Q Wang, L He, ... bioRxiv, 723221, 2019 | 1 | 2019 |
METTL3 modulates colonic epithelium integrity via maintaining the self-renewal and differentiation of Lgr5+ stem cell C Ding, X Yang, H Liu, M Roulis, H Chen, Y Chen, H Xu, Y Gao, J Zhong, ... Journal of Molecular Cell Biology, mjae060, 2025 | | 2025 |
RNA m6A demethylase ALKBH5 regulates the development of γδ T cells R Flavell, C Ding, Z Yu, H Xu, M Roulis, R Qu, J Zhou, A Jarret, R Jackson, ... | | 2020 |
Maren Bacher M Roulis | | 2020 |
SUPPLEMENTARY METHODS M Roulis, G Bongers, M Armaka, T Salviano, Z He, A Singh, U Seidler, ... | | |