| Cryo-EM structure of the human cannabinoid receptor CB2-Gi signaling complex C Xing, Y Zhuang, TH Xu, Z Feng, XE Zhou, M Chen, L Wang, X Meng, ... Cell 180 (4), 645-654. e13, 2020 | 243 | 2020 |
| p62/SQSTM1/Sequestosome-1 is an N-recognin of the N-end rule pathway which modulates autophagosome biogenesis Nat Commun 8 (102), 2017 | 226 | 2017 |
| Modeling, molecular dynamics simulation, and mutation validation for structure of cannabinoid receptor 2 based on known crystal structures of GPCRs Z Feng, MH Alqarni, P Yang, Q Tong, A Chowdhury, L Wang, XQ Xie Journal of chemical information and modeling 54 (9), 2483-2499, 2014 | 114 | 2014 |
| Mechanism of Graphene Oxide as an Enzyme Inhibitor from Molecular Dynamics Simulations X Sun*, Z Feng*, T Hou, Li, Youyong ACS applied materials & interfaces, 2014 | 104 | 2014 |
| Structural insight into tetrameric hTRPV1 from homology modeling, molecular docking, molecular dynamics simulation, virtual screening, and bioassay validations Z Feng, LV Pearce, X Xu, X Yang, P Yang, PM Blumberg, XQ Xie Journal of chemical information and modeling 55 (3), 572-588, 2015 | 74 | 2015 |
| Discovery of novel ligands for TNF-α and TNF receptor-1 through structure-based virtual screening and biological assay S Chen, Z Feng, Y Wang, S Ma, Z Hu, P Yang, Y Chai, X Xie Journal of chemical information and modeling 57 (5), 1101-1111, 2017 | 71 | 2017 |
| Targeted inhibition of the type 2 cannabinoid receptor is a novel approach to reduce renal fibrosis L Zhou, S Zhou, P Yang, Y Tian, Z Feng, XQ Xie, Y Liu Kidney international 94 (4), 756-772, 2018 | 67 | 2018 |
| Studies on the Interactions between β2 Adrenergic Receptor and Gs Protein by Molecular Dynamics Simulations Z Feng, T Hou, Y Li Journal of chemical information and modeling 52 (4), 1005-1014, 2012 | 48 | 2012 |
| The Selective Interaction between Silica Nanoparticles and Enzymes from Molecular Dynamics Simulations Xiaotian Sun*, Zhiwei Feng*, Liling Zhang, Tingjun Hou, Youyong Li Plos one, 2014 | 47 | 2014 |
| Structural insight into the serotonin (5-HT) receptor family by molecular docking, molecular dynamics simulation and systems pharmacology analysis Yuan-qiang Wang, Wei-wei Lin, Nan Wu, Si-yi Wang, Mao-zi Chen, Zhi-hua Lin ... Acta Pharmacologica Sinica (2019), 2019 | 46 | 2019 |
| Allosteric Modulation of Intact γ-Secretase Structural Dynamics JY Lee, Z Feng, XQ Xie, B Ivet Biophysical Journal 113 (12), p2643-2649, 2017 | 45 | 2017 |
| Allosteric Binding Site and Activation Mechanism of Class C G-Protein Coupled Receptors: Metabotropic Glutamate Receptor Family Z Feng, S Ma, G Hu, XQ Xie The AAPS Journal 17 (3), 1-17, 2015 | 42 | 2015 |
| Cardiovascular disease chemogenomics knowledgebase-guided target identification and drug synergy mechanism study of an herbal formula H Zhang, S Ma, Z Feng, D Wang, C Li, Y Cao, X Chen, A Liu, Z Zhu, ... Scientific reports 6 (1), 33963, 2016 | 41 | 2016 |
| Computational advances for the development of allosteric modulators and bitopic ligands in G protein-coupled receptors Z Feng, G Hu, S Ma, XQ Xie The AAPS journal 17 (5), 1080-1095, 2015 | 39 | 2015 |
| Design and activity of AP endonuclease-1 inhibitors Z Feng, S Kochanek, D Close, LR Wang, A Srinivasan, AA Almehizia, ... Journal of Chemical Biology 8 (3), 79-93, 2015 | 37 | 2015 |
| Unidirectional peristaltic movement in multisite drug binding pockets of AcrB from molecular dynamics simulations Z Feng, T Hou, Y Li Molecular BioSystems 8 (10), 2699-2709, 2012 | 36 | 2012 |
| PD-1-Targeted Discovery of Peptide Inhibitors by Virtual Screening, Molecular Dynamics Simulation, and Surface Plasmon Resonance Y Wang, H Guo, Z Feng, S Wang, Y Wang, Q He, G Li, W Lin, XQ Xie, ... Molecules 24 (20), 3784, 2019 | 34 | 2019 |
| A novel small-molecule antagonizes PRMT5-mediated KLF4 methylation for targeted therapy Z Zhou, Z Feng, D Hu, P Yang, M Gur, I Bahar, M Cristofanilli, ... EBioMedicine 44, 98-111, 2019 | 34 | 2019 |
| Difference and Influence of Inactive and Active States of Cannabinoid Receptor Subtype CB2: From Conformation to Drug Discovery J Hu#, Z Feng#, S Ma, Y Zhang, Q Tong, MH Alqarni, X Gou, XQ Xie Journal of Chemical Information and Modeling, 2016 | 34 | 2016 |
| MCCS: a novel recognition pattern-based method for fast track discovery of anti-SARS-CoV-2 drugs Z Feng, M Chen, Y Xue, T Liang, H Chen, Y Zhou, TD Nolin, RB Smith, ... Briefings in bioinformatics 22 (2), 946–962, 2020 | 33 | 2020 |
Tingjun HouQiushi Professor of Pharmaceutical Science, Zhejiang UniversityVerified email at zju.edu.cn