| AT1 receptor signaling pathways in the cardiovascular system T Kawai, SJ Forrester, S O’Brien, A Baggett, V Rizzo, S Eguchi Pharmacological research 125, 4-13, 2017 | 232 | 2017 |
| Epidermal growth factor receptor transactivation: mechanisms, pathophysiology, and potential therapies in the cardiovascular system SJ Forrester, T Kawai, S O'Brien, W Thomas, RC Harris, S Eguchi Annual review of pharmacology and toxicology 56 (1), 627-653, 2016 | 167 | 2016 |
| G protein-coupled receptor-G protein interactions: a single-molecule perspective D Calebiro, Z Koszegi, Y Lanoiselée, T Miljus, S O’Brien Physiological reviews 101 (3), 857-906, 2021 | 105 | 2021 |
| Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis OS Johansen, T Ma, JB Hansen, LK Markussen, R Schreiber, ... Cell 184 (13), 3502-3518. e33, 2021 | 101 | 2021 |
| Spatiotemporal GLP-1 and GIP receptor signaling and trafficking/recycling dynamics induced by selected receptor mono-and dual-agonists A Novikoff, SL O'Brien, M Bernecker, G Grandl, M Kleinert, PJ Knerr, ... Molecular metabolism 49, 101181, 2021 | 59 | 2021 |
| Plasma membrane preassociation drives β-arrestin coupling to receptors and activation J Grimes, Z Koszegi, Y Lanoiselée, T Miljus, SL O’Brien, TM Stepniewski, ... Cell 186 (10), 2238-2255. e20, 2023 | 42 | 2023 |
| How Carvedilol activates β2-adrenoceptors T Benkel, M Zimmermann, J Zeiner, S Bravo, N Merten, VJY Lim, ... Nature Communications 13 (1), 7109, 2022 | 38 | 2022 |
| Autocrine negative feedback regulation of lipolysis through sensing of NEFAs by FFAR4/GPR120 in WAT AS Husted, JH Ekberg, E Tripp, TAD Nissen, S Meijnikman, SL O'Brien, ... Molecular metabolism 42, 101103, 2020 | 29 | 2020 |
| Transactivation of the epidermal growth factor receptor in responses to myocardial stress and cardioprotection ME Reichelt, S O’Brien, WG Thomas, JP Headrick The International Journal of Biochemistry & Cell Biology 83, 97-110, 2017 | 26 | 2017 |
| ADRA1A–Gαq signalling potentiates adipocyte thermogenesis through CKB and TNAP JF Rahbani, C Scholtes, DM Lagarde, MF Hussain, A Roesler, CB Dykstra, ... Nature metabolism 4 (11), 1459-1473, 2022 | 25 | 2022 |
| BRET-based assay to monitor EGFR transactivation by the AT1R reveals Gq/11 protein-independent activation and AT1R-EGFR complexes SL O'Brien, EKM Johnstone, D Devost, J Conroy, ME Reichelt, ... Biochemical pharmacology 158, 232-242, 2018 | 25 | 2018 |
| Cardiac human bitter taste receptors contain naturally occurring variants that alter function CJ Bloxham, KD Hulme, F Fierro, C Fercher, CL Pegg, SL O'Brien, ... Biochemical Pharmacology 219, 115932, 2024 | 7 | 2024 |
| Stimulation of the four isoforms of receptor tyrosine kinase ErbB4, but not ErbB1, confers cardiomyocyte hypertrophy Z Wang, HW Chan, G Gambarotta, NJ Smith, BW Purdue, DJ Pennisi, ... Journal of Cellular Physiology 236 (12), 8160-8170, 2021 | 6 | 2021 |
| Complex interactions between the angiotensin II type 1 receptor, the epidermal growth factor receptor and TRIO-dependent signaling partners EKM Johnstone, RS Abhayawardana, HB See, RM Seeber, SL O'Brien, ... Biochemical Pharmacology 188, 114521, 2021 | 4 | 2021 |
| Single-molecule analysis of receptor-β-arrestin interactions in living cells J Grimes, Z Koszegi, Y Lanoiselée, T Miljus, SL O’Brien, TM Stepniewski, ... bioRxiv, 2022.11. 15.516577, 2022 | 2 | 2022 |
| Combined α-and β-adrenergic receptor activation triggers thermogenesis by the futile creatine cycle L Kazak, J Rahbani, C Scholtes, D Lagarde, MF Hussain, A Roesler, ... | 2 | 2022 |
| A new paradigm of intracrine free fatty acid receptor 4 signaling at lipid droplets E Tripp, SL O’Brien, G Smith, A Boufersaoui, J Roberts, J Pike, J Correia, ... bioRxiv, 2023.07. 28.550805, 2023 | 1 | 2023 |
| Modern Methods to Explore GPCR Signalling in Live Cells E Tripp, S O'Brien, D Calebiro Authorea Preprints, 2022 | 1 | 2022 |
| Endomembrane GPCR signaling: 15 years on, the quest continues D Calebiro, T Miljus, S O’Brien Trends in Biochemical Sciences, 2024 | | 2024 |
| Exploring human rare disease variants from a multidimensional perspective illuminates receptor–G protein coupling diversity T Redfern-Nichols, SL O’Brien, X Huang, B Medel-Lacruz, D Calebiro, ... bioRxiv, 2024.01. 16.575841, 2024 | | 2024 |
