| Distinct cellular dynamics associated with response to CAR-T therapy for refractory B cell lymphoma NJ Haradhvala, MB Leick, K Maurer, SH Gohil, RC Larson, N Yao, ... Nature medicine 28 (9), 1848-1859, 2022 | 159 | 2022 |
| Blockade or deletion of IFNγ reduces macrophage activation without compromising CAR T-cell function in hematologic malignancies SR Bailey, S Vatsa, RC Larson, AA Bouffard, I Scarfò, MC Kann, ... Blood Cancer Discovery 3 (2), 136-153, 2022 | 97 | 2022 |
| Non-cleavable hinge enhances avidity and expansion of CAR-T cells for acute myeloid leukemia MB Leick, H Silva, I Scarfò, R Larson, BD Choi, AA Bouffard, K Gallagher, ... Cancer cell 40 (5), 494-508. e5, 2022 | 96 | 2022 |
| Mesothelin CAR T cells secreting anti-FAP/anti-CD3 molecules efficiently target pancreatic adenocarcinoma and its stroma M Wehrli, S Guinn, F Birocchi, A Kuo, Y Sun, RC Larson, AJ Almazan, ... Clinical Cancer Research 30 (9), 1859-1877, 2024 | 21 | 2024 |
| Comparative analysis of Bcl-2 family protein overexpression in CAR T cells alone and in combination with BH3 mimetics F Korell, ML Olson, D Salas-Benito, MB Leick, RC Larson, A Bouffard, ... Science Translational Medicine 16 (750), eadk7640, 2024 | 6 | 2024 |
| Stealth transgenes enable CAR-T cells to evade host immune responses K Grauwet, T Berger, MC Kann, H Silva, R Larson, MB Leick, SR Bailey, ... Journal for Immunotherapy of Cancer 12 (5), e008417, 2024 | 5 | 2024 |
| Rational chemical and genetic modifications enhance avidity and function of CD70-directed CAR-T-cells for myeloid leukemia MB Leick, H Silva, I Scarfò, R Larson, BD Choi, AA Bouffard, ... Blood 138, 405, 2021 | 3 | 2021 |
| CD70 CAR T cells secreting an anti-CD33/anti-CD3 dual-targeting antibody overcome antigen heterogeneity in AML HJ Silva, G Martin, F Birocchi, M Wehrli, MC Kann, V Supper, A Parker, ... Blood 145 (7), 720-731, 2025 | 1 | 2025 |
| Chimeric antigen receptor (CAR) T cells overexpressing Bcl-xL increase proliferation and antitumor activity alone and in combination with BH3 mimetics F Korell, M Olson, D Salas-Benito, MB Leick, RC Larson, H Silva, ... Cancer Research 83 (7_Supplement), 4098-4098, 2023 | 1 | 2023 |
| Patients with Deleterious Germline Variants in STXBP2 Develop Toxicity after CAR-T Cell Therapy with Axicabtagene Ciloleucel MB Leick, S Han, KME Gallagher, H Silva, G Martin, S Camp, H Chu, ... Blood 140 (Supplement 1), 646-647, 2022 | 1 | 2022 |
| The Role of B Cells in Solid Tumors H Silva, D Sherwin, Y Pylayeva-Gupta Annual Review of Cancer Biology 9, 2024 | | 2024 |
| Abstract B047: Antigenic properties determine the outcome of B cell driven anti-tumor immunity C Sturdevant, N Kren, H Silva, I Gomez, A Hepperla, Y Pylayeva-Gupta Cancer Research 84 (17_Supplement_2), B047-B047, 2024 | | 2024 |
| Combinatorial Effects of BH3 Mimetics and CAR T Cells Targeting T-Cell Lymphomas TB Heavican-Foral, F Korell, I Scarfò, H Silva, A Basanthakumar, ... Blood 140 (Supplement 1), 499-500, 2022 | | 2022 |
| Lenalidomide switch control of CAR T-cell phenotype and function via degradable membrane-bound IL-7 MC Kann, A Tepper, HJ Silva, IC Lane, AA Bouffard, RC Larson, BL Ebert, ... Cancer Research 82 (12_Supplement), 3606-3606, 2022 | | 2022 |
| Mesothelin CAR T cells secreting FAP specific T cell engaging molecule (TEAM) target pancreatic cancer and its tumor microenvironment (TME) M Wehrli, A Kuo, R Larson, I Scarfò, A Bouffard, K Grauwet, M Leick, ... Cancer Research 82 (12_Supplement), 569-569, 2022 | | 2022 |
| IFNg Impedes Antigen-Specific Proliferation of CAR-T with a CD28, but Not 4-1BB, Costimulatory Domain SR Bailey, S Vatsa, H Silva, RC Larson, MC Kann, K Grauwet, MB Leick, ... MOLECULAR THERAPY 30 (4), 46-46, 2022 | | 2022 |
| Engineering Stealth CAR T Cells to Evade the Host Immune Responses K Grauwet, M Kann, H Silva, SR Bailey, RC Larson, T Berger, MJ Frigault, ... MOLECULAR THERAPY 30 (4), 53-53, 2022 | | 2022 |
| Optimized CD70-Targeted CAR Secreting a CD33-Targeted Bispecific T-cell Engager Overcomes Antigen Heterogeneity for Acute Myeloid Leukemia M Leick, H Silva, G Martin, M Kann, M Wehrli, B Choi, A Kuo, R Larson, ... | | 2022 |
