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Olli Silvennoinen
Olli Silvennoinen
Unknown affiliation
Verified email at helsinki.fi
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Cited by
Year
JAK2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoietin
BA Witthuhn, FW Quelle, O Silvennoinen, T Yi, B Tang, O Miura, JN Ihle
Cell 74 (2), 227-236, 1993
14711993
Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 β receptor components
N Stahl, TG Boulton, T Farruggella, NY Ip, S Davis, BA Witthuhn, ...
Science 263 (5143), 92-95, 1994
12751994
Identification of JAK2 as a growth hormone receptor-associated tyrosine kinase
LS Argetsinger, GS Campbell, X Yang, BA Witthuhn, O Silvennoinen, ...
Cell 74 (2), 237-244, 1993
12681993
The protein tyrosine kinase JAK1 complements defects in interferon-α/β and-γ signal transduction
M Müller, J Briscoe, C Laxton, D Guschin, A Ziemiecki, O Silvennoinen, ...
Nature 366 (6451), 129-135, 1993
9601993
Signaling by the cytokine receptor superfamily: JAKs and STATs
JN Ihle, BA Witthuhn, FW Quelle, K Yamamoto, WE Thierfelder, B Kreider, ...
Trends in biochemical sciences 19 (5), 222-227, 1994
8701994
Interaction of IL-2Rβ and γc Chains with Jak1 and Jak3: Implications for XSCID and XCID
SM Russell, JA Johnston, M Noguchi, M Kawamura, CM Bacon, ...
Science 266 (5187), 1042-1045, 1994
8421994
Signaling through the hematopoietic cytokine receptors.
JN Ihle, BA Witthuhn, FW Quelle, K Yamamoto, O Silvennoinen
Annual review of immunology 13, 369-398, 1995
8321995
The janus kinases (jaks)
K Yamaoka, P Saharinen, M Pesu, VET Holt, O Silvennoinen, JJ O'Shea
Genome biology 5, 1-6, 2004
8302004
Involvement of the Jak-3 Janus kinase in signalling by interleukins 2 and 4 in lymphoid and myeloid cells
BA Witthuhn, O Silvennoinen, O Miura, KS Lai, C Cwik, ET Liu, JN Ihle
Nature 370 (6485), 153-157, 1994
7751994
Functional activation of Jak1 and Jak3 by selective association with IL-2 receptor subunits
T Miyazaki, A Kawahara, H Fujii, Y Nakagawa, Y Minami, ZJ Liu, I Oishi, ...
Science 266 (5187), 1045-1047, 1994
7461994
Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction.
O Silvennoinen, BA Witthuhn, FW Quelle, JL Cleveland, T Yi, JN Ihle
Proceedings of the National Academy of Sciences 90 (18), 8429-8433, 1993
6381993
Complementation by the protein tyrosine kinase JAK2 of a mutant cell line defective in the interferon-& gamma; signal transduction pathway
D Watling, D Guschin, M Müller, O Silvennoinen, BA Witthuhn, FW Quelle, ...
Nature 366 (6451), 166-170, 1993
6231993
Regulation of the Jak2 tyrosine kinase by its pseudokinase domain
P Saharinen, K Takaluoma, O Silvennoinen
Molecular and cellular biology 20 (10), 3387-3395, 2000
5132000
Interferon-induced nuclear signalling by Jak protein tyrosine kinases
O Silvennoinen, JN Ihle, J Schlessinger, DE Levy
Nature 366 (6455), 583-585, 1993
4961993
Ras-independent growth factor signaling by transcription factor tyrosine phosphorylation
O Silvennoinen, C Schindler, J Schlessinger, DE Levy
Science 261 (5129), 1736-1739, 1993
4301993
The pseudokinase domain is required for suppression of basal activity of Jak2 and Jak3 tyrosine kinases and for cytokine-inducible activation of signal transduction
P Saharinen, O Silvennoinen
Journal of Biological Chemistry 277 (49), 47954-47963, 2002
4232002
Activation of JAK2 kinase mediated by the interleukin 6 signal transducer gp130.
M Narazaki, BA Witthuhn, K Yoshida, O Silvennoinen, K Yasukawa, ...
Proceedings of the National Academy of Sciences 91 (6), 2285-2289, 1994
3821994
Regulation of Jak2 through the ubiquitin-proteasome pathway involves phosphorylation of Jak2 on Y1007 and interaction with SOCS-1
D Ungureanu, P Saharinen, I Junttila, DJ Hilton, O Silvennoinen
Molecular and cellular biology, 2002
3702002
Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture
AL Lahti, VJ Kujala, H Chapman, AP Koivisto, M Pekkanen-Mattila, ...
Disease models & mechanisms 5 (2), 220-230, 2012
3672012
The pseudokinase domain of JAK2 is a dual-specificity protein kinase that negatively regulates cytokine signaling
D Ungureanu, J Wu, T Pekkala, Y Niranjan, C Young, ON Jensen, CF Xu, ...
Nature structural & molecular biology 18 (9), 971-976, 2011
3402011
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