| Structural insight into enantioselective inversion of an alcohol dehydrogenase reveals a “polar gate” in stereorecognition of diaryl ketones J Zhou, Y Wang, G Xu, L Wu, R Han, U Schwaneberg, Y Rao, YL Zhao, ... Journal of the American Chemical Society 140 (39), 12645-12654, 2018 | 112 | 2018 |
| Hydroclassified Combinatorial Saturation Mutagenesis: Reshaping Substrate Binding Pockets of KpADH for Enantioselective Reduction of Bulky–Bulky Ketones GC Xu, Y Wang, MH Tang, JY Zhou, J Zhao, RZ Han, Y Ni ACS Catalysis 8 (9), 8336-8345, 2018 | 60 | 2018 |
| Stereochemistry in asymmetric reduction of bulky–bulky ketones by alcohol dehydrogenases J Zhou, G Xu, Y Ni ACS Catalysis 10 (19), 10954-10966, 2020 | 57 | 2020 |
| Structure-Guided Engineering of d-Carbamoylase Reveals a Key Loop at Substrate Entrance Tunnel Y Liu, G Xu, J Zhou, J Ni, L Zhang, X Hou, D Yin, Y Rao, YL Zhao, Y Ni ACS Catalysis 10 (21), 12393-12402, 2020 | 46 | 2020 |
| Production of a key chiral intermediate of Betahistine with a newly isolated Kluyveromyces sp. in an aqueous two-phase system Y Ni, J Zhou, Z Sun Process Biochemistry 47 (7), 1042-1048, 2012 | 44 | 2012 |
| Scalable biocatalytic synthesis of optically pure ethyl (R)-2-hydroxy-4-phenylbutyrate using a recombinant E. coli with high catalyst yield Y Ni, Y Su, H Li, J Zhou, Z Sun Journal of biotechnology 168 (4), 493-498, 2013 | 42 | 2013 |
| Carbonyl group-dependent high-throughput screening and enzymatic characterization of diaromatic ketone reductase J Zhou, G Xu, R Han, J Dong, W Zhang, R Zhang, Y Ni Catalysis Science & Technology 6 (16), 6320-6327, 2016 | 39 | 2016 |
| Efficient production of hyaluronic acid by Streptococcus zooepidemicus using two-stage semi-continuous fermentation Y Zhang, J Dong, G Xu, R Han, J Zhou, Y Ni Bioresource Technology 377, 128896, 2023 | 22 | 2023 |
| Fine tuning the enantioselectivity and substrate specificity of alcohol dehydrogenase from Kluyveromyces polysporus by single residue at 237 Y Wang, W Dai, Y Liu, Z Zhang, J Zhou, G Xu, Y Ni Catalysis Communications 108, 1-6, 2018 | 21 | 2018 |
| Engineering of cyclodextrin glycosyltransferase reveals pH-regulated mechanism of enhanced long-chain glycosylated sophoricoside specificity R Han, J Ni, J Zhou, J Dong, G Xu, Y Ni Applied and environmental microbiology 86 (7), e00004-20, 2020 | 14 | 2020 |
| Molecular switch manipulating Prelog priority of an alcohol dehydrogenase toward bulky-bulky ketones G Xu, W Dai, Y Wang, L Zhang, Z Sun, J Zhou, Y Ni Molecular Catalysis 484, 110741, 2020 | 14 | 2020 |
| Engineering an Alcohol Dehydrogenase from Kluyveromyces polyspora for Efficient Synthesis of Ibrutinib Intermediate Y Wu, J Zhou, J Ni, C Zhu, Z Sun, G Xu, Y Ni Advanced Synthesis & Catalysis 364 (2), 332-340, 2022 | 12 | 2022 |
| Two enantiocomplementary Baeyer-Villiger monooxygenases newly identified for asymmetric oxyfunctionalization of thioether S Wei, Y Liu, J Zhou, G Xu, Y Ni Molecular Catalysis 513, 111784, 2021 | 10 | 2021 |
| Structure-based engineering of ω-transaminase for enhanced catalytic efficiency toward (R)-(+)-1-(1-naphthyl) ethylamine synthesis R Han, X Cao, H Fang, J Zhou, Y Ni Molecular Catalysis 502, 111368, 2021 | 10 | 2021 |
| Engineering an alcohol dehydrogenase for balancing kinetics in NADPH regeneration with 1, 4-butanediol as a cosubstrate G Xu, C Zhu, A Li, Y Ni, R Han, J Zhou, Y Ni ACS Sustainable Chemistry & Engineering 7 (18), 15706-15714, 2019 | 10 | 2019 |
| Engineering the Thermostability of a d-Carbamoylase Based on Ancestral Sequence Reconstruction for the Efficient Synthesis of d-Tryptophan J Hu, X Chen, L Zhang, J Zhou, G Xu, Y Ni Journal of Agricultural and Food Chemistry 71 (1), 660-670, 2022 | 9 | 2022 |
| Co-immobilized alcohol dehydrogenase and glucose dehydrogenase with resin extraction for continuous production of chiral diaryl alcohol J Zhou, Y Wu, Q Zhang, G Xu, Y Ni Applied Biochemistry and Biotechnology 193, 2742-2758, 2021 | 9 | 2021 |
| Stereodivergent evolution of KpADH for the asymmetric reduction of diaryl ketones with para-substituents J Zhang, J Zhou, G Xu, Y Ni Molecular Catalysis 524, 112315, 2022 | 8 | 2022 |
| Engineering of a Baeyer–Villiger monooxygenase reveals key residues for the asymmetric oxidation of omeprazole sulfide S Wei, G Xu, L Zhang, J Zhou, Y Ni Chemical Communications 58 (95), 13246-13249, 2022 | 8 | 2022 |
| Self-Sufficient In Vitro Multi-Enzyme Cascade for Efficient Synthesis of Danshensu from l-DOPA R Han, K Gao, Y Jiang, J Zhou, G Xu, J Dong, U Schwaneberg, Y Ji, Y Ni ACS Synthetic Biology 12 (1), 277-286, 2022 | 5 | 2022 |
