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Francesco De Pascali
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Human LH and hCG stimulate differently the early signalling pathways but result in equal testosterone synthesis in mouse Leydig cells in vitro
L Riccetti, F De Pascali, L Gilioli, F Potì, LB Giva, M Marino, S Tagliavini, ...
Reproductive Biology and Endocrinology 15, 1-12, 2017
1232017
Follicle-stimulating hormone potentiates the steroidogenic activity of chorionic gonadotropin and the anti-apoptotic activity of luteinizing hormone in human granulosa-lutein …
L Casarini, L Riccetti, F De Pascali, A Nicoli, S Tagliavini, T Trenti, ...
Molecular and cellular endocrinology 422, 103-114, 2016
842016
Estrogen modulates specific life and death signals induced by LH and hCG in human primary granulosa cells in vitro
L Casarini, L Riccetti, F De Pascali, L Gilioli, M Marino, E Vecchi, D Morini, ...
International journal of molecular sciences 18 (5), 926, 2017
702017
β-arrestin signalling and bias in hormone-responsive GPCRs
E Reiter, MA Ayoub, LP Pellissier, F Landomiel, A Musnier, A Tréfier, ...
Molecular and cellular endocrinology 449, 28-41, 2017
472017
Biased signaling and allosteric modulation at the FSHR
F Landomiel, F De Pascali, P Raynaud, F Jean-Alphonse, R Yvinec, ...
Frontiers in endocrinology 10, 148, 2019
412019
Genetics of gonadotropins and their receptors as markers of ovarian reserve and response in controlled ovarian stimulation
L Riccetti, F De Pascali, L Gilioli, D Santi, G Brigante, M Simoni, ...
Best Practice & Research Clinical Obstetrics & Gynaecology 44, 15-25, 2017
382017
Membrane estrogen receptor (GPER) and follicle-stimulating hormone receptor (FSHR) heteromeric complexes promote human ovarian follicle survival
L Casarini, C Lazzaretti, E Paradiso, S Limoncella, L Riccetti, S Sperduti, ...
Iscience 23 (12), 2020
362020
Follicle-Stimulating Hormone Receptor: Advances and Remaining Challenges
F De Pascali, A Tréfier, F Landomiel, V Bozon, G Bruneau, R Yvinec, ...
International Review of Cell and Molecular Biology 338, 1-58, 2018
342018
Glycosylation Pattern and in vitro Bioactivity of Reference Follitropin alfa and Biosimilars
L Riccetti, S Sperduti, C Lazzaretti, D Klett, F De Pascali, E Paradiso, ...
Frontiers in endocrinology 10, 503, 2019
292019
β-arrestins and biased signaling in gonadotropin receptors.
F De Pascali, E Reiter
Minerva ginecologica 70 (5), 525-538, 2018
212018
In silico identification of a β2-adrenoceptor allosteric site that selectively augments canonical β2AR-Gs signaling and function
SD Shah, C Lind, F De Pascali, RB Penn, AD MacKerell Jr, ...
Proceedings of the National Academy of Sciences 119 (49), e2214024119, 2022
202022
Direct impact of gonadotropins on glucose uptake and storage in preovulatory granulosa cells: Implications in the pathogenesis of polycystic ovary syndrome
N Chahal, A Geethadevi, S Kaur, R Lakra, A Nagendra, TG Shrivastav, ...
Metabolism 115, 154458, 2021
202021
Pharmacological programming of endosomal signaling activated by small molecule ligands of the follicle stimulating hormone receptor
S Sposini, F De Pascali, R Richardson, NS Sayers, D Perrais, HN Yu, ...
Frontiers in Pharmacology 11, 593492, 2020
182020
Inferring biallelism of two FSH receptor mutations associated with spontaneous ovarian hyperstimulation syndrome by evaluating FSH, LH and HCG cross-activity
C Lazzaretti, L Riccetti, S Sperduti, C Anzivino, G Brigante, F De Pascali, ...
Reproductive biomedicine online 38 (5), 816-824, 2019
182019
Identification of a β-arrestin-biased negative allosteric modulator for the β2-adrenergic receptor
M Ippolito, F De Pascali, N Hopfinger, KE Komolov, D Laurinavichyute, ...
Proceedings of the National Academy of Sciences 120 (31), e2302668120, 2023
122023
Characterization of a new WHIM syndrome mutant reveals mechanistic differences in regulation of the chemokine receptor CXCR4
J Luo, F De Pascali, GW Richmond, AM Khojah, JL Benovic
Journal of Biological Chemistry 298 (2), 2022
112022
Pharmacological Characterization of Low Molecular Weight Biased Agonists at the Follicle Stimulating Hormone Receptor
F De Pascali, MA Ayoub, R Benevelli, S Sposini, J Lehoux, N Gallay, ...
International Journal of Molecular Sciences 22 (18), 9850, 2021
112021
β2‐Adrenoceptor agonist profiling reveals biased signalling phenotypes for the β2‐adrenoceptor with possible implications for the treatment of asthma
F De Pascali, M Ippolito, E Wolfe, KE Komolov, N Hopfinger, D Lemenze, ...
British Journal of Pharmacology 179 (19), 4692-4708, 2022
102022
Nuclear expression of VDR and AHR is mutually exclusive in glandular cells in endometriosis
F De Pascali, L Casarini, C Kuhn, M Simoni, S Mahner, U Jeschke, ...
Histochemistry and Cell Biology 156 (4), 391-399, 2021
92021
Phenylalanine 193 in extracellular loop 2 of the β2-adrenergic receptor coordinates β-arrestin interaction
M Ippolito, F De Pascali, A Inoue, JL Benovic
Molecular Pharmacology 101 (2), 87-94, 2022
62022
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Articles 1–20