Tetramer dissociation and monomer partial unfolding precedes protofibril formation in amyloidogenic transthyretin variants A Quintas, DC Vaz, I Cardoso, MJM Saraiva, RMM Brito Journal of Biological Chemistry 276 (29), 27207-27213, 2001 | 422 | 2001 |
Extracellular alpha-synuclein oligomers modulate synaptic transmission and impair LTP via NMDA-receptor activation MJ Diógenes, RB Dias, DM Rombo, HV Miranda, F Maiolino, P Guerreiro, ... Journal of Neuroscience 32 (34), 11750-11762, 2012 | 309 | 2012 |
Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathies H Vicente Miranda, ÉM Szegő, LMA Oliveira, C Breda, E Darendelioglu, ... Brain 140 (5), 1399-1419, 2017 | 227 | 2017 |
The tetrameric protein transthyretin dissociates to a non-native monomer in solution: a novel model for amyloidogenesis A Quintas, MJM Saraiva, RMM Brito Journal of Biological Chemistry 274 (46), 32943-32949, 1999 | 216 | 1999 |
The amyloidogenic potential of transthyretin variants correlates with their tendency to aggregate in solution A Quintas, MJM Saraiva, RMM Brito Febs Letters 418 (3), 297-300, 1997 | 132 | 1997 |
Insulin glycation by methylglyoxal results in native-like aggregation and inhibition of fibril formation LMA Oliveira, A Lages, RA Gomes, H Neves, C Família, AV Coelho, ... BMC biochemistry 12, 1-13, 2011 | 130 | 2011 |
Argpyrimidine, a methylglyoxal-derived advanced glycation end-product in familial amyloidotic polyneuropathy R Gomes, M Sousa Silva, A Quintas, C Cordeiro, A Freire, P Pereira, ... Biochemical Journal 385 (2), 339-345, 2005 | 130 | 2005 |
Dopamine-induced conformational changes in alpha-synuclein TF Outeiro, J Klucken, K Bercury, J Tetzlaff, P Putcha, LMA Oliveira, ... PloS one 4 (9), e6906, 2009 | 89 | 2009 |
Prediction of peptide and protein propensity for amyloid formation C Família, SR Dennison, A Quintas, DA Phoenix PloS one 10 (8), e0134679, 2015 | 83 | 2015 |
Bioquimica-organização molecular da vida A Quintas, AP Freire, MJ Halpern Lisboa: Lidel, 2008 | 72 | 2008 |
Insights into the molecular mechanism of protein native-like aggregation upon glycation LMA Oliveira, RA Gomes, D Yang, SR Dennison, C Família, A Lages, ... Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1834 (6), 1010-1022, 2013 | 67 | 2013 |
Comparative calorimetric study of non-amyloidogenic and amyloidogenic variants of the homotetrameric protein transthyretin VL Shnyrov, E Villar, GG Zhadan, JM Sanchez-Ruiz, A Quintas, ... Biophysical Chemistry 88 (1-3), 61-67, 2000 | 65 | 2000 |
Protein glycation in vivo: functional and structural effects on yeast enolase RA Gomes, LMA Oliveira, M Silva, C Ascenso, A Quintas, G Costa, ... Biochemical journal 416 (3), 317-326, 2008 | 64 | 2008 |
Energy-independent translocation of cell-penetrating peptides occurs without formation of pores. A biophysical study with pep-1 S Troeira Henriques, A Quintas, LA Bagatolli, F Homblé, MARB Castanho Molecular membrane biology 24 (4), 282-293, 2007 | 64 | 2007 |
Extraction procedures for hair forensic toxicological analysis: a mini-review C Ferreira, C Paulino, A Quintas Chemical research in toxicology 32 (12), 2367-2381, 2019 | 48 | 2019 |
Evolutionary and structural features of the C2, V3 and C3 envelope regions underlying the differences in HIV-1 and HIV-2 biology and infection H Barroso, P Borrego, I Bártolo, JM Marcelino, C Família, A Quintas, ... PloS one 6 (1), e14548, 2011 | 48 | 2011 |
Probing Surface Properties of Cytochrome c at Au Bionanoconjugates I Gomes, NC Santos, LMA Oliveira, A Quintas, P Eaton, E Pereira, ... The Journal of Physical Chemistry C 112 (42), 16340-16347, 2008 | 48 | 2008 |
An ancestral HIV-2/simian immunodeficiency virus peptide with potent HIV-1 and HIV-2 fusion inhibitor activity P Borrego, R Calado, JM Marcelino, P Pereira, A Quintas, H Barroso, ... Aids 27 (7), 1081-1090, 2013 | 39 | 2013 |
Inflammatory factors, genetic variants, and predisposition for preterm birth J Couceiro, I Matos, JJ Mendes, PV Baptista, AR Fernandes, A Quintas Clinical Genetics 100 (4), 357-367, 2021 | 37 | 2021 |
Resistance to antibody neutralization in HIV-2 infection occurs in late stage disease and is associated with X4 tropism JM Marcelino, P Borrego, C Nilsson, C Família, H Barroso, F Maltez, ... Aids 26 (18), 2275-2284, 2012 | 37 | 2012 |