Identification of DHODH as a therapeutic target in small cell lung cancer L Li, SR Ng, CI Colón, BJ Drapkin, PP Hsu, Z Li, CS Nabel, CA Lewis, ... Science translational medicine 11 (517), eaaw7852, 2019 | 109 | 2019 |
Foxa2 and Cdx2 cooperate with Nkx2-1 to inhibit lung adenocarcinoma metastasis CMC Li, V Gocheva, MJ Oudin, A Bhutkar, SY Wang, SR Date, SR Ng, ... Genes & development 29 (17), 1850-1862, 2015 | 100 | 2015 |
CRISPR-mediated modeling and functional validation of candidate tumor suppressor genes in small cell lung cancer SR Ng, WM Rideout, EH Akama-Garren, A Bhutkar, KL Mercer, ... Proceedings of the National Academy of Sciences, 2019 | 80 | 2019 |
RPL39L is an example of a recently evolved ribosomal protein paralog that shows highly specific tissue expression patterns and is upregulated in ESCs and HCC tumors QWL Wong, J Li, SR Ng, SG Lim, H Yang, LA Vardy RNA biology 11 (1), 33-41, 2014 | 70 | 2014 |
Optofluidic real-time cell sorter for longitudinal CTC studies in mouse models of cancer B Hamza, SR Ng, SM Prakadan, FF Delgado, CR Chin, EM King, LF Yang, ... Proceedings of the National Academy of Sciences 116 (6), 2232-2236, 2019 | 62 | 2019 |
Keap1 mutation renders lung adenocarcinomas dependent on Slc33a1 R Romero, FJ Sánchez-Rivera, PMK Westcott, KL Mercer, A Bhutkar, ... Nature Cancer 1 (6), 589-602, 2020 | 55 | 2020 |
Measuring kinetics and metastatic propensity of CTCs by blood exchange between mice B Hamza, AB Miller, L Meier, M Stockslager, SR Ng, EM King, L Lin, ... Nature Communications 12 (1), 1-11, 2021 | 32 | 2021 |
Integrative multiomics enhancer activity profiling identifies therapeutic vulnerabilities in cholangiocarcinoma of different etiologies JH Hong, CH Yong, HL Heng, JY Chan, MC Lau, J Chen, JY Lee, AH Lim, ... Gut 73 (6), 966-984, 2024 | 13 | 2024 |
PBRM1-deficient PBAF complexes target aberrant genomic loci to activate the NF-κB pathway in clear cell renal cell carcinoma X Yao, JH Hong, AM Nargund, MSW Ng, HL Heng, Z Li, P Guan, ... Nature cell biology 25 (5), 765-777, 2023 | 11 | 2023 |
Identification of DHODH as a therapeutic target in small cell lung cancer. Sci Transl Med 11 (517) L Li, SR Ng, CI Colon, BJ Drapkin, PP Hsu, Z Li | 5 | 2019 |
Therapeutic and immunomodulatory potential of pazopanib in malignant phyllodes tumor DYX Ng, Z Li, E Lee, JST Kok, JY Lee, J Koh, CCY Ng, AH Lim, W Liu, ... NPJ Breast Cancer 8 (1), 44, 2022 | 4 | 2022 |
Abstract A24: Using single-cell RNA-seq approaches to decipher heterogeneity in autochthonous mouse models of small cell lung cancer ND Marjanovic, SR Ng, A Regev, T Jacks Clinical Cancer Research 24 (17_Supplement), A24-A24, 2018 | 2 | 2018 |
Abstract A12: CRISPR-mediated modeling and functional validation of candidate tumor-suppressor genes in small cell lung cancer SR Ng, WM Rideout III, BL Wagner, T Jacks Cancer Research 78 (10_Supplement), A12-A12, 2018 | 1 | 2018 |
CRISPR-mediated interrogation of small cell lung cancer SR Ng Massachusetts Institute of Technology, 2018 | 1 | 2018 |
Effects of RARα ligand binding domain mutations on breast fibroepithelial tumor function and signaling XX Huang, LM Ng, PH Lee, P Guan, MJ Chow, ABM Bashir, M Lau, ... npj Breast Cancer 11 (1), 1, 2025 | | 2025 |
A Lung Cancer Mouse Model Database L Cai, Y Gao, RJ DeBerardinis, G Acquaah-Mensah, V Aidinis, JE Beane, ... bioRxiv, 2024 | | 2024 |
Abstract LT09: Integrative Multi-Omics Enhancer Activity Profiling Identifies Therapeutic Vulnerabilities in Cholangiocarcinoma of Different Etiologies JH Hong, CH Yong, HL Heng, JY Chan, MC Lau, J Chen, JY Lee, AH Lim, ... Cancer Research 84 (8_Supplement), LT09-LT09, 2024 | | 2024 |
Effects of breast fibroepithelial tumor associated retinoic acid receptor alpha ligand binding domain mutations on receptor function and retinoid signaling XX Huang, LM Ng, PH Lee, P Guan, MJ Chow, AB Mohamed Bashir, ... bioRxiv, 2022.12. 01.518133, 2022 | | 2022 |
57P Therapeutic vulnerability of malignant phyllodes tumour to pazopanib identified through a novel patient-derived xenograft and cell line model DYX Ng, Z Li, E Lee, J Koh, CCY Ng, A Lim, L Wei, SR Ng, KS Lim, Y Sim, ... Annals of Oncology 31, S1264, 2020 | | 2020 |