Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases W Xu, H Yang, Y Liu, Y Yang, P Wang, SH Kim, S Ito, C Yang, P Wang, ... Cancer cell 19 (1), 17-30, 2011 | 3213 | 2011 |
Structural basis for cooperative function of Mettl3 and Mettl14 methyltransferases P Wang, KA Doxtader, Y Nam Molecular cell 63 (2), 306-317, 2016 | 1114 | 2016 |
Crystal structure of TET2-DNA complex: insight into TET-mediated 5mC oxidation L Hu, Z Li, J Cheng, Q Rao, W Gong, M Liu, YG Shi, J Zhu, P Wang, Y Xu Cell 155 (7), 1545-1555, 2013 | 493 | 2013 |
Structural insights into the YAP and TEAD complex Z Li, B Zhao, P Wang, F Chen, Z Dong, H Yang, KL Guan, Y Xu Genes & development 24 (3), 235-240, 2010 | 431 | 2010 |
Lysine-5 acetylation negatively regulates lactate dehydrogenase A and is decreased in pancreatic cancer D Zhao, SW Zou, Y Liu, X Zhou, Y Mo, P Wang, YH Xu, B Dong, Y Xiong, ... Cancer cell 23 (4), 464-476, 2013 | 350 | 2013 |
Crystal structure of the YTH domain of YTHDF2 reveals mechanism for recognition of N6-methyladenosine T Zhu, IA Roundtree, P Wang, X Wang, L Wang, C Sun, Y Tian, J Li, C He, ... Cell research 24 (12), 1493-1496, 2014 | 347 | 2014 |
Structural basis for regulation of METTL16, an S-adenosylmethionine homeostasis factor KA Doxtader, P Wang, AM Scarborough, D Seo, NK Conrad, Y Nam Molecular cell 71 (6), 1001-1011. e4, 2018 | 203 | 2018 |
Molecular mechanism for USP7-mediated DNMT1 stabilization by acetylation J Cheng, H Yang, J Fang, L Ma, R Gong, P Wang, Z Li, Y Xu Nature communications 6 (1), 7023, 2015 | 152 | 2015 |
Hemi-methylated DNA opens a closed conformation of UHRF1 to facilitate its histone recognition J Fang, J Cheng, J Wang, Q Zhang, M Liu, R Gong, P Wang, X Zhang, ... Nature communications 7 (1), 11197, 2016 | 136 | 2016 |
Structural insight into coordinated recognition of trimethylated histone H3 lysine 9 (H3K9me3) by the plant homeodomain (PHD) and tandem tudor domain (TTD) of UHRF1 (ubiquitin … J Cheng, Y Yang, J Fang, J Xiao, T Zhu, F Chen, P Wang, Z Li, H Yang, ... Journal of Biological Chemistry 288 (2), 1329-1339, 2013 | 131 | 2013 |
Structure function analysis of an ADP-ribosyltransferase type III effector and its RNA-binding target in plant immunity B Jeong, Y Lin, A Joe, M Guo, C Korneli, H Yang, P Wang, M Yu, ... Journal of Biological Chemistry 286 (50), 43272-43281, 2011 | 112 | 2011 |
Crystal structure of the Gtr1p–Gtr2p complex reveals new insights into the amino acid-induced TORC1 activation R Gong, L Li, Y Liu, P Wang, H Yang, L Wang, J Cheng, KL Guan, Y Xu Genes & development 25 (16), 1668-1673, 2011 | 107 | 2011 |
Structural insight into mechanisms for dynamic regulation of PKM2 P Wang, C Sun, T Zhu, Y Xu Protein & cell 6 (4), 275-287, 2015 | 105 | 2015 |
LSD2/KDM1B and its cofactor NPAC/GLYR1 endow a structural and molecular model for regulation of H3K4 demethylation R Fang, F Chen, Z Dong, D Hu, AJ Barbera, EA Clark, J Fang, Y Yang, ... Molecular cell 49 (3), 558-570, 2013 | 104 | 2013 |
Crystal structure of PHD domain of UHRF1 and insights into recognition of unmodified histone H3 arginine residue 2 L Hu, Z Li, P Wang, Y Lin, Y Xu Cell research 21 (9), 1374-1378, 2011 | 102 | 2011 |
Identification of FDA approved drugs targeting COVID-19 virus by structure-based drug repositioning A Farag, P Wang, M Ahmed, H Sadek | 82 | 2020 |
Structural insights into a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans Y Yang, L Hu, P Wang, H Hou, Y Lin, Y Liu, Z Li, R Gong, X Feng, L Zhou, ... Cell Research 20 (8), 886-898, 2010 | 57 | 2010 |
Structural insight into substrate recognition by histone demethylase LSD2/KDM1b F Chen, H Yang, Z Dong, J Fang, P Wang, T Zhu, W Gong, R Fang, ... Cell research 23 (2), 306-309, 2013 | 56 | 2013 |
Lipopolysaccharide‐evoked activation of p38 and JNK leads to an increase in ICAM‐1 expression in Schwann cells of sciatic nerves A Shen, J Yang, Y Gu, D Zhou, L Sun, Y Qin, J Chen, P Wang, F Xiao, ... The FEBS journal 275 (17), 4343-4353, 2008 | 44 | 2008 |
Coordinated regulation of active and repressive histone methylations by a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans H Lin, Y Wang, Y Wang, F Tian, P Pu, Y Yu, H Mao, Y Yang, P Wang, L Hu, ... Cell Research 20 (8), 899-907, 2010 | 35 | 2010 |