Microglia/macrophage polarization dynamics reveal novel mechanism of injury expansion after focal cerebral ischemia X Hu, P Li, Y Guo, H Wang, RK Leak, S Chen, Y Gao, J Chen Stroke 43 (11), 3063-3070, 2012 | 1567 | 2012 |
Microglial and macrophage polarization—new prospects for brain repair X Hu, RK Leak, Y Shi, J Suenaga, Y Gao, P Zheng, J Chen Nature Reviews Neurology 11 (1), 56-64, 2015 | 1392 | 2015 |
Microglia/macrophage polarization dynamics in white matter after traumatic brain injury G Wang, J Zhang, X Hu, L Zhang, L Mao, X Jiang, AKF Liou, RK Leak, ... Journal of Cerebral Blood Flow & Metabolism 33 (12), 1864-1874, 2013 | 505 | 2013 |
Cerebral vascular disease and neurovascular injury in ischemic stroke X Hu, TM De Silva, J Chen, FM Faraci Circulation research 120 (3), 449-471, 2017 | 438 | 2017 |
Interleukin-4 is essential for microglia/macrophage M2 polarization and long-term recovery after cerebral ischemia X Liu, J Liu, S Zhao, H Zhang, W Cai, M Cai, X Ji, RK Leak, Y Gao, J Chen, ... Stroke 47 (2), 498-504, 2016 | 417 | 2016 |
Rapid endothelial cytoskeletal reorganization enables early blood–brain barrier disruption and long-term ischaemic reperfusion brain injury Y Shi, L Zhang, H Pu, L Mao, X Hu, X Jiang, N Xu, RA Stetler, F Zhang, ... Nature communications 7 (1), 10523, 2016 | 385 | 2016 |
HDAC inhibition prevents white matter injury by modulating microglia/macrophage polarization through the GSK3β/PTEN/Akt axis G Wang, Y Shi, X Jiang, RK Leak, X Hu, Y Wu, H Pu, WW Li, B Tang, ... Proceedings of the National Academy of Sciences 112 (9), 2853-2858, 2015 | 360 | 2015 |
Astrogliosis in CNS pathologies: is there a role for microglia? D Zhang, X Hu, L Qian, JP O’Callaghan, JS Hong Molecular neurobiology 41, 232-241, 2010 | 359 | 2010 |
Adoptive regulatory T‐cell therapy protects against cerebral ischemia P Li, YU Gan, BL Sun, F Zhang, B Lu, Y Gao, W Liang, AW Thomson, ... Annals of neurology 74 (3), 458-471, 2013 | 326 | 2013 |
Aging of cerebral white matter H Liu, Y Yang, Y Xia, W Zhu, RK Leak, Z Wei, J Wang, X Hu Ageing research reviews 34, 64-76, 2017 | 299 | 2017 |
Dysfunction of the neurovascular unit in ischemic stroke and neurodegenerative diseases: an aging effect W Cai, K Zhang, P Li, L Zhu, J Xu, B Yang, X Hu, Z Lu, J Chen Ageing research reviews 34, 77-87, 2017 | 274 | 2017 |
Treg cell-derived osteopontin promotes microglia-mediated white matter repair after ischemic stroke L Shi, Z Sun, W Su, F Xu, D Xie, Q Zhang, X Dai, K Iyer, TK Hitchens, ... Immunity 54 (7), 1527-1542. e8, 2021 | 253 | 2021 |
Enhanced oligodendrogenesis and recovery of neurological function by erythropoietin after neonatal hypoxic/ischemic brain injury M Iwai, RA Stetler, J Xing, X Hu, Y Gao, W Zhang, J Chen, G Cao Stroke 41 (5), 1032-1037, 2010 | 253 | 2010 |
Preconditioning provides neuroprotection in models of CNS disease: paradigms and clinical significance RA Stetler, RK Leak, Y Gan, P Li, F Zhang, X Hu, Z Jing, J Chen, ... Progress in neurobiology 114, 58-83, 2014 | 224 | 2014 |
Molecular dialogs between the ischemic brain and the peripheral immune system: dualistic roles in injury and repair C An, Y Shi, P Li, X Hu, Y Gan, RA Stetler, RK Leak, Y Gao, BL Sun, ... Progress in neurobiology 115, 6-24, 2014 | 221 | 2014 |
Peroxisome proliferator-activated receptor γ (PPARγ): A master gatekeeper in CNS injury and repair W Cai, T Yang, H Liu, L Han, K Zhang, X Hu, X Zhang, KJ Yin, Y Gao, ... Progress in neurobiology 163, 27-58, 2018 | 218 | 2018 |
STAT6/Arg1 promotes microglia/macrophage efferocytosis and inflammation resolution in stroke mice W Cai, X Dai, J Chen, J Zhao, M Xu, L Zhang, B Yang, W Zhang, M Rocha, ... JCI insight 4 (20), 2019 | 213 | 2019 |
Novel neuroprotective mechanisms of memantine: increase in neurotrophic factor release from astroglia and anti-inflammation by preventing microglial activation HM Wu, NS Tzeng, L Qian, SJ Wei, X Hu, SH Chen, SM Rawls, P Flood, ... Neuropsychopharmacology 34 (10), 2344-2357, 2009 | 207 | 2009 |
Omega-3 fatty acids protect the brain against ischemic injury by activating Nrf2 and upregulating heme oxygenase 1 M Zhang, S Wang, L Mao, RK Leak, Y Shi, W Zhang, X Hu, B Sun, G Cao, ... Journal of Neuroscience 34 (5), 1903-1915, 2014 | 205 | 2014 |
ST2/IL-33-dependent microglial response limits acute ischemic brain injury Y Yang, H Liu, H Zhang, Q Ye, J Wang, B Yang, L Mao, W Zhu, RK Leak, ... Journal of Neuroscience 37 (18), 4692-4704, 2017 | 201 | 2017 |