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| Targeting RNA foci in iPSC-derived motor neurons from ALS patients with a C9ORF72 repeat expansion D Sareen, JG O’Rourke, P Meera, A Muhammad, S Grant, M Simpkinson, ... Science translational medicine 5 (208), 208ra149-208ra149, 2013 | 807 | 2013 |
| Targeted degradation of sense and antisense C9orf72 RNA foci as therapy for ALS and frontotemporal degeneration C Lagier-Tourenne, M Baughn, F Rigo, S Sun, P Liu, HR Li, J Jiang, ... Proceedings of the National Academy of Sciences 110 (47), E4530-E4539, 2013 | 699 | 2013 |
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| Sense-encoded poly-GR dipeptide repeat proteins correlate to neurodegeneration and uniquely co-localize with TDP-43 in dendrites of repeat-expanded C9orf72 amyotrophic lateral … S Saberi, JE Stauffer, J Jiang, SD Garcia, AE Taylor, D Schulte, T Ohkubo, ... Acta neuropathologica 135 (3), 459-474, 2018 | 214 | 2018 |
| Sporadic ALS has compartment-specific aberrant exon splicing and altered cell–matrix adhesion biology SJ Rabin, JMH Kim, M Baughn, RT Libby, YJ Kim, Y Fan, RT Libby, ... Human molecular genetics 19 (2), 313-328, 2010 | 167 | 2010 |
| Frequency and complexity of de novo structural mutation in autism WM Brandler, D Antaki, M Gujral, A Noor, G Rosanio, TR Chapman, ... The American Journal of Human Genetics 98 (4), 667-679, 2016 | 124 | 2016 |
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| Mechanism of STMN2 cryptic splice-polyadenylation and its correction for TDP-43 proteinopathies MW Baughn, Z Melamed, J López-Erauskin, MS Beccari, K Ling, A Zuberi, ... Science 379 (6637), 1140-1149, 2023 | 99 | 2023 |
| Transcriptome–pathology correlation identifies interplay between TDP-43 and the expression of its kinase CK1E in sporadic ALS F Krach, R Batra, EC Wheeler, AQ Vu, R Wang, K Hutt, SJ Rabin, ... Acta neuropathologica 136, 405-423, 2018 | 87 | 2018 |
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| Stathmin-2 loss leads to neurofilament-dependent axonal collapse driving motor and sensory denervation J Lopez-Erauskin, M Bravo-Hernandez, M Presa, MW Baughn, ... Nature neuroscience 27 (1), 34-47, 2024 | 29 | 2024 |
| Gene expression signatures of sporadic ALS motor neuron populations R Batra, K Hutt, A Vu, SJ Rabin, MW Baughn, RT Libby, S Hoon, J Ravits, ... BioRxiv, 038448, 2016 | 26 | 2016 |
| Cryptic splicing of stathmin-2 and UNC13A mRNAs is a pathological hallmark of TDP-43-associated Alzheimer’s disease AR Agra Almeida Quadros, Z Li, X Wang, IS Ndayambaje, S Aryal, ... Acta Neuropathologica 147 (1), 9, 2024 | 21 | 2024 |
| ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS J López-Erauskin, T Tadokoro, MW Baughn, B Myers, ... Neuron 106 (2), 354, 2020 | 12 | 2020 |
| Methods for modulating expression of c9orf72 antisense transcript CF Bennett, F Rigo, DW Cleveland, C Lagier-Tourenne, JM Ravits, ... US Patent App. 15/029,210, 2016 | 11 | 2016 |
| GOLGA8 increases bulk antisense oligonucleotide uptake and activity in mammalian cells MA McMahon, M Rahdar, S Mukhopadhyay, HH Bui, C Hart, S Damle, ... Molecular Therapy-Nucleic Acids 32, 289-301, 2023 | 4 | 2023 |
| Therapeutic Restoration of Stathmin-2 RNA Processing in TDP-43 Proteinopathies MW Baughn University of California, San Diego, 2021 | 1 | 2021 |
John RavitsUniversity of California, San DiegoVerified email at ucsd.edu