| Mathematical modeling identifies Lck as a potential mediator for PD-1 induced inhibition of early TCR signaling T Arulraj, D Barik PloS one 13 (10), e0206232, 2018 | 28 | 2018 |
| BTG1 mutation yields supercompetitive B cells primed for malignant transformation C Mlynarczyk, M Teater, J Pae, CR Chin, L Wang, T Arulraj, D Barisic, ... Science 379 (6629), eabj7412, 2023 | 26 | 2023 |
| Synchronous germinal center onset impacts the efficiency of antibody responses T Arulraj, SC Binder, PA Robert, M Meyer-Hermann Frontiers in immunology 10, 2116, 2019 | 24 | 2019 |
| Germinal centre shutdown T Arulraj, SC Binder, PA Robert, M Meyer-Hermann Frontiers in immunology 12, 705240, 2021 | 23 | 2021 |
| Ymir: A 3D structural affinity model for multi-epitope vaccine simulations PA Robert, T Arulraj, M Meyer-Hermann Iscience 24 (9), 2021 | 20 | 2021 |
| Rate of immune complex cycling in follicular dendritic cells determines the extent of protecting antigen integrity and availability to germinal center B cells T Arulraj, SC Binder, M Meyer-Hermann The Journal of Immunology 206 (7), 1436-1442, 2021 | 20 | 2021 |
| A transcriptome-informed QSP model of metastatic triple-negative breast cancer identifies predictive biomarkers for PD-1 inhibition T Arulraj, H Wang, LA Emens, CA Santa-Maria, AS Popel Science Advances 9 (26), eadg0289, 2023 | 15 | 2023 |
| Generating immunogenomic data-guided virtual patients using a QSP model to predict response of advanced NSCLC to PD-L1 inhibition H Wang, T Arulraj, H Kimko, AS Popel npj Precision Oncology 7 (1), 55, 2023 | 14 | 2023 |
| From virtual patients to digital twins in immuno-oncology: lessons learned from mechanistic quantitative systems pharmacology modeling H Wang, T Arulraj, A Ippolito, AS Popel NPJ Digital Medicine 7 (1), 189, 2024 | 8 | 2024 |
| Investigating the mechanism of germinal center shutdown T Arulraj, SC Binder, M Meyer-Hermann Frontiers in Immunology 13, 922318, 2022 | 8 | 2022 |
| A mathematical modelling tool for unravelling the antibody-mediated effects on CTLA-4 interactions A Ganesan, T Arulraj, T Choulli, KH Barakat BMC Medical Informatics and Decision Making 18, 1-17, 2018 | 8 | 2018 |
| Leveraging multi-omics data to empower quantitative systems pharmacology in immuno-oncology T Arulraj, H Wang, A Ippolito, S Zhang, EJ Fertig, AS Popel Briefings in bioinformatics 25 (3), bbae131, 2024 | 7 | 2024 |
| Virtual patient analysis identifies strategies to improve the performance of predictive biomarkers for PD-1 blockade T Arulraj, H Wang, A Deshpande, R Varadhan, LA Emens, EM Jaffee, ... Proceedings of the National Academy of Sciences 121 (45), e2410911121, 2024 | 2 | 2024 |
| Quantitative systems pharmacology modeling of macrophage‐targeted therapy combined with PD‐L1 inhibition in advanced NSCLC H Wang, T Arulraj, S Anbari, AS Popel Clinical and Translational Science 17 (6), e13811, 2024 | 2 | 2024 |
| Antibody mediated intercommunication of germinal centers T Arulraj, SC Binder, M Meyer-Hermann Cells 11 (22), 3680, 2022 | 2 | 2022 |
| Identifying biomarkers for treatment of uveal melanoma by T cell engager using a QSP model S Anbari, H Wang, T Arulraj, M Nickaeen, M Pilvankar, J Wang, S Hansel, ... npj Systems Biology and Applications 10 (1), 108, 2024 | 1 | 2024 |
| Germinal centers are permissive to subdominant antibody responses PA Robert, T Arulraj, M Meyer-Hermann Frontiers in Immunology 14, 1238046, 2024 | 1 | 2024 |
| Predicting response to PD-L1 inhibition in NSCLC using a quantitative systems pharmacology model guided by immunogenomic data H Wang, T Arulraj, AS Popel Cancer Research 83 (7_Supplement), 5697-5697, 2023 | 1 | 2023 |
| BTG1 Mutation Promotes Aggressive Lymphoma Development By Lowering the Threshold to MYC Activation and Generating “Super-Competitor” B Cells C Mlynarczyk, M Teater, J Pae, T Arulraj, CR Chin, L Wang, J Ersching, ... Blood 138, 359, 2021 | 1 | 2021 |
| In Silico Analysis of the Longevity and Timeline of Individual Germinal Center Reactions in a Primary Immune Response T Arulraj, SC Binder, M Meyer-Hermann Cells 10 (7), 1736, 2021 | 1 | 2021 |
Michael Meyer-HermannProfessor of Theoretical BiologyVerified email at helmholtz-hzi.de
