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jayant thatte
jayant thatte
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Local-pooled-error test for identifying differentially expressed genes with a small number of replicated microarrays
N Jain, J Thatte, T Braciale, K Ley, M O'Connell, JK Lee
Bioinformatics 19 (15), 1945-1951, 2003
3892003
The chemokine KC, but not monocyte chemoattractant protein-1, triggers monocyte arrest on early atherosclerotic endothelium
Y Huo, C Weber, SB Forlow, M Sperandio, J Thatte, M Mack, S Jung, ...
The Journal of clinical investigation 108 (9), 1307-1314, 2001
3492001
Preferential migration of effector CD8+ T cells into the interstitium of the normal lung
E Galkina, J Thatte, V Dabak, MB Williams, K Ley, TJ Braciale
The Journal of clinical investigation 115 (12), 3473-3483, 2005
2362005
Therapeutic Utility of Cannabinoid Receptor Type 2 (CB2) Selective Agonists
S Han, J Thatte, DJ Buzard, RM Jones
Journal of medicinal chemistry 56 (21), 8224-8256, 2013
1662013
LFA-1 is required for retention of effector CD8 T cells in mouse lungs
J Thatte, V Dabak, MB Williams, TJ Braciale, K Ley
Blood 101 (12), 4916-4922, 2003
1072003
A CD2-green fluorescence protein-transgenic mouse reveals very late antigen-4-dependent CD8+ lymphocyte rolling in inflamed venules
K Singbartl, J Thatte, ML Smith, K Wethmar, K Day, K Ley
The Journal of Immunology 166 (12), 7520-7526, 2001
902001
Immunization with live versus killed Salmonella typhimurium leads to the generation of an IFN-γ-dominant versus an IL-4-dominant immune response
J Thatte, S Rath, V Bal
International immunology 5 (11), 1431-1436, 1993
861993
α4β1 Integrin (VLA-4) Blockade Attenuates both Early and Late Leukocyte Recruitment and Neointimal Growth following Carotid Injury in Apolipoprotein E (–/–) Mice
KG Barringhaus, JW Phillips, JS Thatte, JM Sanders, AC Czarnik, ...
Journal of vascular research 41 (3), 252-260, 2004
682004
Discovery of APD334: design of a clinical stage functional antagonist of the sphingosine-1-phosphate-1 receptor
DJ Buzard, SH Kim, L Lopez, A Kawasaki, X Zhu, J Moody, L Thoresen, ...
ACS Medicinal Chemistry Letters 5 (12), 1313-1317, 2014
672014
Recent progress in the development of selective S1P1 receptor agonists for the treatment of inflammatory and autoimmune disorders
DJ Buzard, J Thatte, M Lerner, J Edwards, RM Jones
Expert Opinion on Therapeutic Patents 18 (10), 1141-1159, 2008
602008
Differential requirements for core2 glucosaminyltransferase for endothelial L-selectin ligand function in vivo
M Sperandio, SB Forlow, J Thatte, LG Ellies, JD Marth, K Ley
The Journal of Immunology 167 (4), 2268-2274, 2001
542001
Endogenous oocyte antigens are required for rapid induction and progression of autoimmune ovarian disease following day-3 thymectomy
P Alard, C Thompson, SS Agersborg, J Thatte, Y Setiady, E Samy, ...
The Journal of Immunology 166 (7), 4363-4369, 2001
482001
Analysis of immunization route-related variation in the immune response to heat-killed Salmonella typhimurium in mice
J Thatte, S Rath, V Bal
Infection and Immunity 63 (1), 99-103, 1995
481995
Discovery of APD371: Identification of a Highly Potent and Selective CB2 Agonist for the Treatment of Chronic Pain
S Han, L Thoresen, JK Jung, X Zhu, J Thatte, M Solomon, I Gaidarov, ...
ACS Medicinal Chemistry Letters 8 (12), 1309-1313, 2017
472017
Induction of a type 1 regulatory CD4 T cell response following Vβ8. 2 DNA vaccination results in immune deviation and protection from experimental autoimmune encephalomyelitis
V Kumar, J Maglione, J Thatte, B Pederson, E Sercarz, ES Ward
International immunology 13 (6), 835-841, 2001
472001
Compositions as adjuvants to improve immune responses to vaccines and methods of use
W Hoo, E Jensen, T Moll, D Carlo, B Helmich, SP Yei, J Thatte
US Patent App. 11/087,177, 2005
382005
Fused tricyclic indoles as S1P1 agonists with robust efficacy in animal models of autoimmune disease
DJ Buzard, S Han, L Lopez, A Kawasaki, J Moody, L Thoresen, B Ullman, ...
Bioorganic & medicinal chemistry letters 22 (13), 4404-4409, 2012
222012
Design and synthesis of new tricyclic indoles as potent modulators of the S1P1 receptor
DJ Buzard, TO Schrader, X Zhu, J Lehmann, B Johnson, M Kasem, ...
Bioorganic & Medicinal Chemistry Letters 25 (3), 659-663, 2015
202015
Discovery of 2-(7-(5-phenyl-1, 2, 4-oxadiazol-3-yl)-1, 2, 3, 4-tetrahydrocyclopenta [b] indol-3-yl) acetic acids: Potent and selective sphingosine-1-phosphate (S1P (1 …
S Han, L Thoresen, J Moody, DJ Buzard, L Lopez, C Sage, J Edwards, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 241, 2011
192011
(7-Benzyloxy-2,3-dihydro-1H-pyrrolo[1,2-a]indol-1-yl)acetic Acids as S1P1 Functional Antagonists
DJ Buzard, L Lopez, J Moody, A Kawasaki, TO Schrader, M Kasem, ...
ACS Medicinal Chemistry Letters 5 (12), 1334-1339, 2014
172014
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