Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases MTN Yarnall, EI Ioannidi, C Schmitt-Ulms, RN Krajeski, J Lim, L Villiger, ... Nature Biotechnology 41 (4), 500-512, 2023 | 307 | 2023 |
Spatiotemporal control of CRISPR/Cas9 function in cells and zebrafish using light‐activated guide RNA W Zhou, W Brown, A Bardhan, M Delaney, AS Ilk, RR Rauen, SI Kahn, ... Angewandte Chemie International Edition 59 (23), 8998-9003, 2020 | 109 | 2020 |
Programmable eukaryotic protein synthesis with RNA sensors by harnessing ADAR K Jiang, J Koob, XD Chen, RN Krajeski, Y Zhang, V Volf, W Zhou, ... Nature Biotechnology 41 (5), 698-707, 2023 | 69 | 2023 |
Structure and engineering of the type III-E CRISPR-Cas7-11 effector complex K Kato, W Zhou, S Okazaki, Y Isayama, T Nishizawa, JS Gootenberg, ... Cell 185 (13), 2324-2337. e16, 2022 | 69 | 2022 |
Conditional control of CRISPR/Cas9 function W Zhou, A Deiters Angewandte Chemie International Edition 55 (18), 5394-5399, 2016 | 65 | 2016 |
RNA-triggered protein cleavage and cell growth arrest by the type III-E CRISPR nuclease-protease K Kato, S Okazaki, C Schmitt-Ulms, K Jiang, W Zhou, J Ishikawa, ... Science 378 (6622), 882-889, 2022 | 42 | 2022 |
Regulating CRISPR/Cas9 function through conditional guide RNA control W Brown, W Zhou, A Deiters ChemBioChem 22 (1), 63-72, 2021 | 34 | 2021 |
Chemogenetic and optogenetic control of post-translational modifications through genetic code expansion W Zhou, A Deiters Current opinion in chemical biology 63, 123-131, 2021 | 25 | 2021 |
Optical control of MAP kinase kinase 6 (MKK6) reveals that it has divergent roles in pro-apoptotic and anti-proliferative signaling SMT Rahman, W Zhou, A Deiters, JM Haugh Journal of Biological Chemistry 295 (25), 8494-8504, 2020 | 22 | 2020 |
Genetic code expansion in mammalian cells: A plasmid system comparison W Zhou, JS Wesalo, J Liu, A Deiters Bioorganic & medicinal chemistry 28 (24), 115772, 2020 | 21 | 2020 |
Optical control of cellular ATP levels with a photocaged adenylate kinase W Zhou, CP Hankinson, A Deiters ChemBioChem 21 (13), 1832-1836, 2020 | 21 | 2020 |
Optical Control of Base Editing and Transcription through Light‐Activated Guide RNA W Zhou, W Brown, A Bardhan, M Tsang, A Deiters ChemPhotoChem 5 (11), 984-988, 2021 | 7 | 2021 |
Optogenetic Control of Phosphatase and Kinase Function A Ryan, W Zhou, KE Shoger, TM Courtney, RA Gottschalk, A Deiters The FASEB Journal 36, 2022 | 1 | 2022 |
Programmable rna writing using crispr effectors and trans-splicing templates OO Abudayyeh, JS Gootenberg, W Zhou, A Kayabolen, CF Schmitt-Ulms US Patent App. 18/455,380, 2024 | | 2024 |
Dissection of MKK6 and p38 Signaling Using Light‐Activated Protein Kinases SMT Rahman, W Zhou, A Deiters, JM Haugh ChemBioChem 25 (1), e202300551, 2024 | | 2024 |
Systems, methods, and compositions for rna-guided rna-targeting crispr effectors OO Abudayyeh, JS Gootenberg, W Zhou, H Nishimasu, K Kato, ... US Patent App. 18/322,675, 2023 | | 2023 |
Isoform-specific optical activation of kinase function reveals p38-ERK signaling crosstalk W Zhou, A Ryan, CP Janosko, KE Shoger, JM Haugh, RA Gottschalk, ... RSC Chemical Biology 4 (10), 765-773, 2023 | | 2023 |
Optical Control of CRISPR/Cas9 and Kinase Function W Zhou University of Pittsburgh, 2022 | | 2022 |