Inflammasome activation in infected macrophages drives COVID-19 pathology E Sefik, R Qu, C Junqueira, E Kaffe, H Mirza, J Zhao, JR Brewer, A Han, ... Nature 606 (7914), 585-593, 2022 | 443 | 2022 |
Paracrine orchestration of intestinal tumorigenesis by a mesenchymal niche M Roulis, A Kaklamanos, M Schernthanner, P Bielecki, J Zhao, E Kaffe, ... Nature 580 (7804), 524-529, 2020 | 252 | 2020 |
Distinct modes of mitochondrial metabolism uncouple T cell differentiation and function W Bailis, JA Shyer, J Zhao, JCG Canaveras, FJ Al Khazal, R Qu, ... Nature 571 (7765), 403-407, 2019 | 208 | 2019 |
Enteric nervous system-derived IL-18 orchestrates mucosal barrier immunity A Jarret, R Jackson, C Duizer, ME Healy, J Zhao, JM Rone, P Bielecki, ... Cell 180 (1), 50-63. e12, 2020 | 192 | 2020 |
m6A demethylase ALKBH5 controls CD4+ T cell pathogenicity and promotes autoimmunity J Zhou, X Zhang, J Hu, R Qu, Z Yu, H Xu, H Chen, L Yan, C Ding, Q Zou, ... Science Advances 7 (25), eabg0470, 2021 | 137 | 2021 |
A humanized mouse model of chronic COVID-19 E Sefik, B Israelow, H Mirza, J Zhao, R Qu, E Kaffe, E Song, S Halene, ... Nature biotechnology 40 (6), 906-920, 2022 | 98 | 2022 |
IL-10 constrains sphingolipid metabolism to limit inflammation AG York, MH Skadow, J Oh, R Qu, QD Zhou, WY Hsieh, WK Mowel, ... Nature 627 (8004), 628-635, 2024 | 53 | 2024 |
RNA m6A demethylase ALKBH5 regulates the development of γδ T cells C Ding, H Xu, Z Yu, M Roulis, R Qu, J Zhou, J Oh, J Crawford, Y Gao, ... Proceedings of the National Academy of Sciences 119 (33), e2203318119, 2022 | 40 | 2022 |
Humanized mouse liver reveals endothelial control of essential hepatic metabolic functions E Kaffe, M Roulis, J Zhao, R Qu, E Sefik, H Mirza, J Zhou, Y Zheng, ... Cell 186 (18), 3793-3809. e26, 2023 | 33 | 2023 |
Decomposing a deterministic path to mesenchymal niche formation by two intersecting morphogen gradients R Qu, K Gupta, D Dong, Y Jiang, B Landa, C Saez, G Strickland, ... Developmental cell 57 (8), 1053-1067. e5, 2022 | 24 | 2022 |
The age of bone marrow dictates the clonality of smooth muscle-derived cells in atherosclerotic plaques I Kabir, X Zhang, JM Dave, R Chakraborty, R Qu, RR Chandran, A Ntokou, ... Nature aging 3 (1), 64-81, 2023 | 20 | 2023 |
Postnatal developmental trajectory of sex-biased gene expression in the mouse pituitary gland H Hou, C Chan, KE Yuki, D Sokolowski, A Roy, R Qu, L Uusküla-Reimand, ... Biology of sex Differences 13 (1), 57, 2022 | 18 | 2022 |
Unsupervised cross-domain prerequisite chain learning using variational graph autoencoders I Li, V Yan, T Li, R Qu, D Radev arXiv preprint arXiv:2105.03505, 2021 | 16 | 2021 |
A humanized mouse model of chronic COVID-19 to evaluate disease mechanisms and treatment options E Sefik, B Israelow, J Zhao, R Qu, E Song, H Mirza, E Kaffe, S Halene, ... Research square, 2021 | 15 | 2021 |
Multi-omics investigation of innate navitoclax resistance in triple-negative breast cancer cells M Marczyk, GA Patwardhan, J Zhao, R Qu, X Li, VB Wali, AK Gupta, ... Cancers 12 (9), 2551, 2020 | 15 | 2020 |
RNAex: an RNA secondary structure prediction server enhanced by high-throughput structure-probing data Y Wu, R Qu, Y Huang, B Shi, M Liu, Y Li, ZJ Lu Nucleic acids research 44 (W1), W294-W301, 2016 | 14 | 2016 |
Pazopanib ameliorates acute lung injuries via inhibition of MAP3K2 and MAP3K3 Q Yuan, A Basit, W Liang, R Qu, Y Luan, C Ren, A Li, X Xu, X Liu, C Yang, ... Science translational medicine 13 (591), eabc2499, 2021 | 13 | 2021 |
Autologous humanized PDX modeling for immuno-oncology recapitulates features of the human tumor microenvironment M Chiorazzi, J Martinek, B Krasnick, Y Zheng, KJ Robbins, R Qu, ... Journal for ImmunoTherapy of Cancer 11 (7), 2023 | 11 | 2023 |
Gene trajectory inference for single-cell data by optimal transport metrics R Qu, X Cheng, E Sefik, JS Stanley III, B Landa, F Strino, S Platt, ... Nature Biotechnology, 1-11, 2024 | 10 | 2024 |
Integrated transcriptome and trajectory analysis of cutaneous T-cell lymphoma identifies putative precancer populations J Ren, R Qu, NT Rahman, JM Lewis, ALO King, X Liao, FN Mirza, ... Blood Advances 7 (3), 445-457, 2023 | 9 | 2023 |