A hierarchical regulatory network analysis of the vitamin D induced transcriptome reveals novel regulators and complete VDR dependency in monocytes T Warwick, MH Schulz, S Günther, R Gilsbach, A Neme, C Carlberg, ... Scientific reports 11 (1), 6518, 2021 | 43 | 2021 |
HIF1α-AS1 is a DNA: DNA: RNA triplex-forming lncRNA interacting with the HUSH complex MS Leisegang, JK Bains, S Seredinski, JA Oo, NM Krause, CC Kuo, ... Nature communications 13 (1), 6563, 2022 | 30 | 2022 |
The endocannabinoid anandamide has an anti-inflammatory effect on CCL2 expression in vascular smooth muscle cells B Pflüger-Müller, JA Oo, J Heering, T Warwick, E Proschak, S Günther, ... Basic Research in Cardiology 115, 1-16, 2020 | 28 | 2020 |
Computational methods to study DNA: DNA: RNA triplex formation by lncRNAs T Warwick, RP Brandes, MS Leisegang Non-coding RNA 9 (1), 10, 2023 | 20 | 2023 |
Long non-coding RNA PCAT19 safeguards DNA in quiescent endothelial cells by preventing uncontrolled phosphorylation of RPA2 JA Oo, K Pálfi, T Warwick, I Wittig, C Prieto-Garcia, V Matkovic, ... Cell reports 41 (7), 2022 | 18 | 2022 |
The endothelial-enriched lncRNA LINC00607 mediates angiogenic function F Boos, JA Oo, T Warwick, S Günther, J Izquierdo Ponce, M Lopez, D Rafii, ... Basic research in cardiology 118 (1), 5, 2023 | 17* | 2023 |
Reactive oxygen species differentially modulate the metabolic and transcriptomic response of endothelial cells N Müller, T Warwick, K Noack, PF Malacarne, AJL Cooper, N Weissmann, ... Antioxidants 11 (2), 434, 2022 | 14 | 2022 |
A universal model of RNA. DNA: DNA triplex formation accurately predicts genome-wide RNA–DNA interactions T Warwick, S Seredinski, NM Krause, JK Bains, L Althaus, JA Oo, ... Briefings in bioinformatics 23 (6), bbac445, 2022 | 13 | 2022 |
Nox4 promotes endothelial differentiation through chromatin remodeling F Hahner, F Moll, T Warwick, DM Hebchen, GK Buchmann, J Epah, ... Redox biology 55, 102381, 2022 | 13 | 2022 |
Nuclear receptor activation shapes spatial genome organization essential for gene expression control: Lessons learned from the vitamin D receptor T Warwick, MH Schulz, R Gilsbach, RP Brandes, S Seuter Nucleic acids research 50 (7), 3745-3763, 2022 | 13 | 2022 |
DNA topoisomerase inhibition with the HIF inhibitor acriflavine promotes transcription of lncRNAs in endothelial cells S Seredinski, F Boos, S Günther, JA Oo, T Warwick, JI Ponce, FF Lillich, ... Molecular Therapy-Nucleic Acids 27, 1023-1035, 2022 | 13 | 2022 |
ZNF354C is a transcriptional repressor that inhibits endothelial angiogenic sprouting JA Oo, B Irmer, S Günther, T Warwick, K Pálfi, J Izquierdo Ponce, ... Scientific reports 10 (1), 19079, 2020 | 12 | 2020 |
The hydrogen-peroxide producing NADPH oxidase 4 does not limit neointima development after vascular injury in mice GK Buchmann, C Schürmann, M Spaeth, W Abplanalp, L Tombor, D John, ... Redox biology 45, 102050, 2021 | 9 | 2021 |
Epoxyeicosatrienoic acid and prostanoid crosstalk at the receptor and intracellular signaling levels to maintain vascular tone PF Malacarne, J Bezzenberger, M Lopez, T Warwick, N Müller, ... International journal of molecular sciences 23 (11), 5939, 2022 | 8 | 2022 |
RNA-DNA triplexes: molecular mechanisms and functional relevance MS Leisegang, T Warwick, J Stötzel, RP Brandes Trends in Biochemical Sciences, 2024 | 7 | 2024 |
Loss of endothelial cytochrome P450 reductase induces vascular dysfunction in mice PF Malacarne, C Ratiu, A Gajos-Draus, N Müller, M Lopez, ... Hypertension 79 (6), 1216-1226, 2022 | 5 | 2022 |
Acute injury to the mouse carotid artery provokes a distinct healing response T Warwick, GK Buchmann, B Pflüger-Müller, M Spaeth, C Schürmann, ... Frontiers in Physiology 14, 1125864, 2023 | 3 | 2023 |
The endocannabinoid anandamide mediates anti‐inflammatory effects through activation of NR4A nuclear receptors T Teichmann, B Pflüger‐Müller, VMM Giménez, F Sailer, H Dirks, S Zehr, ... British Journal of Pharmacology, 2024 | 2 | 2024 |
Endothelial deletion of the cytochrome P450 reductase leads to cardiac remodelling M Lopez, PF Malacarne, DP Ramanujam, T Warwick, N Müller, J Hu, ... Frontiers in Physiology 13, 1056369, 2022 | 2 | 2022 |
Acetylation alchemy: how Nat10 shapes vascular health T Warwick, L Kurian, RP Brandes European Heart Journal, ehae822, 2024 | 1 | 2024 |