Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms DE Gordon, J Hiatt, M Bouhaddou, VV Rezelj, S Ulferts, H Braberg, ... Science 370 (6521), eabe9403, 2020 | 684 | 2020 |
An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike M Schoof, B Faust, RA Saunders, S Sangwan, V Rezelj, N Hoppe, ... Science 370 (6523), 1473-1479, 2020 | 414 | 2020 |
Affinity maturation of a potent family of HIV antibodies is primarily focused on accommodating or avoiding glycans F Garces, JH Lee, N de Val, AT de la Pena, L Kong, C Puchades, Y Hua, ... Immunity 43 (6), 1053-1063, 2015 | 226 | 2015 |
Structure of the mitochondrial inner membrane AAA+ protease YME1 gives insight into substrate processing C Puchades, AJ Rampello, M Shin, CJ Giuliano, RL Wiseman, SE Glynn, ... Science 358 (6363), eaao0464, 2017 | 223 | 2017 |
The molecular principles governing the activity and functional diversity of AAA+ proteins C Puchades, CR Sandate, GC Lander Nature Reviews Molecular Cell Biology 21 (1), 43-58, 2020 | 213 | 2020 |
Reciprocal degradation of YME1L and OMA1 adapts mitochondrial proteolytic activity during stress TK Rainbolt, J Lebeau, C Puchades, RL Wiseman Cell reports 14 (9), 2041-2049, 2016 | 181 | 2016 |
CryoEM and AI reveal a structure of SARS-CoV-2 Nsp2, a multifunctional protein involved in key host processes. M Gupta, CM Azumaya, M Moritz, S Pourmal, A Diallo, GE Merz, G Jang, ... Research square, 2021 | 82 | 2021 |
Unique structural features of the mitochondrial AAA+ protease AFG3L2 reveal the molecular basis for activity in health and disease C Puchades, B Ding, A Song, RL Wiseman, GC Lander, SE Glynn Molecular cell 75 (5), 1073-1085. e6, 2019 | 82 | 2019 |
Structural basis for distinct operational modes and protease activation in AAA+ protease Lon M Shin, C Puchades, A Asmita, N Puri, E Adjei, RL Wiseman, AW Karzai, ... Science advances 6 (21), eaba8404, 2020 | 68 | 2020 |
Epitope mapping of diverse influenza Hemagglutinin drug candidates using HDX-MS C Puchades, B Kűkrer, O Diefenbach, E Sneekes-Vriese, J Juraszek, ... Scientific reports 9 (1), 4735, 2019 | 42 | 2019 |
Identification of a drug binding pocket in TMEM16F calcium-activated ion channel and lipid scramblase S Feng, C Puchades, J Ko, H Wu, Y Chen, EE Figueroa, S Gu, TW Han, ... Nature Communications 14 (1), 4874, 2023 | 18 | 2023 |
Consortium QSB, Walter P, Manglik A M Schoof, B Faust, RA Saunders, S Sangwan, V Rezelj, N Hoppe, ... Science 370 (6523), 1473, 2020 | 10 | 2020 |
Frozen in Action: Mitochondrial ATPase Proteases under the Electron Microscope C Puchades-Garcia The Scripps Research Institute, 2019 | | 2019 |
Establishing Rhodobacter Sphaeroides for Expression of Large Mitocondrial Membrane Complex YME1L for Cryo-EM Structural Studies C Puchades, LR Wiseman, G Lander Biophysical Journal 112 (3), 356a, 2017 | | 2017 |