Activation of the hypothalamic-pituitary-adrenal stress axis induces cellular oxidative stress JG Spiers, HJC Chen, C Sernia, NA Lavidis Frontiers in neuroscience 8, 456, 2015 | 308 | 2015 |
Mid‐to late term hypoxia in the mouse alters placental morphology, glucocorticoid regulatory pathways and nutrient transporters in a sex‐specific manner JSM Cuffe, SL Walton, RR Singh, JG Spiers, H Bielefeldt‐Ohmann, ... The Journal of physiology 592 (14), 3127-3141, 2014 | 128 | 2014 |
Response of the nitrergic system to activation of the neuroendocrine stress axis HJC Chen, JG Spiers, C Sernia, NA Lavidis Frontiers in neuroscience 9, 3, 2015 | 59 | 2015 |
Inhibition of neuroinflammatory nitric oxide signaling suppresses glycation and prevents neuronal dysfunction in mouse prion disease JM Bourgognon, JG Spiers, SW Robinson, H Scheiblich, P Glynn, C Ortori, ... Proceedings of the National Academy of Sciences 118 (10), e2009579118, 2021 | 46 | 2021 |
Dysregulation of stress systems and nitric oxide signaling underlies neuronal dysfunction in Alzheimer’s disease JG Spiers, HJC Chen, JM Bourgognon, JR Steinert Free Radical Biology and Medicine 134, 468-483, 2019 | 46 | 2019 |
Acute restraint stress induces specific changes in nitric oxide production and inflammatory markers in the rat hippocampus and striatum HJC Chen, JG Spiers, C Sernia, NA Lavidis Free Radical Biology and Medicine 90, 219-229, 2016 | 44 | 2016 |
Acute restraint stress induces rapid and prolonged changes in erythrocyte and hippocampal redox status JG Spiers, HJ Chen, AJ Bradley, ST Anderson, C Sernia, NA Lavidis Psychoneuroendocrinology 38 (11), 2511-2519, 2013 | 40 | 2013 |
Acute restraint stress induces rapid changes in central redox status and protective antioxidant genes in rats JG Spiers, HJC Chen, JSM Cuffe, C Sernia, NA Lavidis Psychoneuroendocrinology 67, 104-112, 2016 | 37 | 2016 |
Nitric oxide-mediated posttranslational modifications control neurotransmitter release by modulating complexin farnesylation and enhancing its clamping ability SW Robinson, JM Bourgognon, JG Spiers, C Breda, S Campesan, ... PLoS biology 16 (4), e2003611, 2018 | 36 | 2018 |
Reactive nitrogen species contribute to the rapid onset of redox changes induced by acute immobilization stress in rats HJC Chen, JG Spiers, C Sernia, ST Anderson, NA Lavidis Stress 17 (6), 520-527, 2014 | 35 | 2014 |
Alterations in neuronal metabolism contribute to the pathogenesis of prion disease JM Bourgognon, JG Spiers, H Scheiblich, A Antonov, SJ Bradley, ... Cell Death & Differentiation 25 (8), 1408-1425, 2018 | 33 | 2018 |
Drosophila Nrf2/Keap1 Mediated Redox Signaling Supports Synaptic Function and Longevity and Impacts on Circadian Activity JG Spiers, C Breda, S Robinson, F Giorgini, JR Steinert Frontiers in Molecular Neuroscience 12, 86, 2019 | 30 | 2019 |
Extracellular vesicles with diagnostic and therapeutic potential for prion diseases A Khadka, JG Spiers, L Cheng, AF Hill Cell and tissue research 392 (1), 247-267, 2023 | 24 | 2023 |
Behavioral phenotyping of a rat model of the BDNF Val66Met polymorphism reveals selective impairment of fear memory EJ Jaehne, JN Kent, EJ Antolasic, BJ Wright, JG Spiers, KC Creutzberg, ... Translational psychiatry 12 (1), 93, 2022 | 24 | 2022 |
Redox stress and metal dys-homeostasis appear as hallmarks of early prion disease pathogenesis in mice JG Spiers, HJC Chen, TL Barry, JM Bourgognon, JR Steinert Free Radical Biology and Medicine 192, 182-190, 2022 | 18 | 2022 |
Inhibition of fatty acid amide hydrolase by PF-3845 alleviates the nitrergic and proinflammatory response in rat hippocampus following acute stress HJC Chen, JG Spiers, C Sernia, NA Lavidis International Journal of Neuropsychopharmacology 21 (8), 786-795, 2018 | 18 | 2018 |
Maternal hypomagnesemia alters hippocampal NMDAR subunit expression and programs anxiety-like behaviour in adult offspring RN Schlegel, JG Spiers, KM Moritz, CL Cullen, ST Björkman, ... Behavioural Brain Research 328, 39-47, 2017 | 18 | 2017 |
Restraint stress alters expression of glucocorticoid bioavailability mediators, suppresses Nrf2, and promotes oxidative stress in liver tissue HJC Chen, T Yip, JK Lee, J Juliani, C Sernia, AF Hill, NA Lavidis, ... Antioxidants 9 (9), 853, 2020 | 16 | 2020 |
Sub-acute restraint stress progressively increases oxidative/nitrosative stress and inflammatory markers while transiently upregulating antioxidant gene expression in the rat … HJC Chen, JK Lee, T Yip, C Sernia, NA Lavidis, JG Spiers Free Radical Biology and Medicine 130, 446-457, 2019 | 16 | 2019 |
Assessing students’ ability to critically evaluate evidence in an inquiry-based undergraduate laboratory course K Colthorpe, H Mehari Abraha, K Zimbardi, L Ainscough, JG Spiers, ... Advances in Physiology Education 41 (1), 154-162, 2017 | 16 | 2017 |