Structure of the KvAP voltage-dependent K+ channel and its dependence on the lipid membrane SY Lee, A Lee, J Chen, R MacKinnon Proceedings of the National Academy of Sciences 102 (43), 15441-15446, 2005 | 390 | 2005 |
Structure of the cold-and menthol-sensing ion channel TRPM8 Y Yin, M Wu, L Zubcevic, WF Borschel, GC Lander, SY Lee Science 359 (6372), 237-241, 2018 | 318 | 2018 |
A membrane-access mechanism of ion channel inhibition by voltage sensor toxins from spider venom SY Lee, R MacKinnon Nature 430 (6996), 232-235, 2004 | 317 | 2004 |
Cryo-electron microscopy structure of the TRPV2 ion channel L Zubcevic, MA Herzik Jr, BC Chung, Z Liu, GC Lander, SY Lee Nature structural & molecular biology 23 (2), 180-186, 2016 | 298 | 2016 |
Crystal structure of MraY, an essential membrane enzyme for bacterial cell wall synthesis BC Chung, J Zhao, RA Gillespie, DY Kwon, Z Guan, J Hong, P Zhou, ... Science 341 (6149), 1012-1016, 2013 | 250 | 2013 |
Regulation of the transcriptional activator NtrC1: structural studies of the regulatory and AAA+ ATPase domains SY Lee, A De La Torre, D Yan, S Kustu, BT Nixon, DE Wemmer Genes & development 17 (20), 2552-2563, 2003 | 249 | 2003 |
Crystal structure of an activated response regulator bound to its target SY Lee, HS Cho, JG Pelton, D Yan, RK Henderson, DS King, L Huang, ... Nature structural biology 8 (1), 52-56, 2001 | 223 | 2001 |
Structural basis of cooling agent and lipid sensing by the cold-activated TRPM8 channel Y Yin, SC Le, AL Hsu, MJ Borgnia, H Yang, SY Lee Science 363 (6430), eaav9334, 2019 | 220 | 2019 |
Crystal structure of activated CheY: comparison with other activated receiver domains SY Lee, HS Cho, JG Pelton, D Yan, EA Berry, DE Wemmer Journal of Biological Chemistry 276 (19), 16425-16431, 2001 | 209 | 2001 |
Dimeric subunit stoichiometry of the human voltage-dependent proton channel Hv1 SY Lee, JA Letts, R MacKinnon Proceedings of the National Academy of Sciences 105 (22), 7692-7695, 2008 | 198 | 2008 |
Beryllofluoride mimics phosphorylation of NtrC and other bacterial response regulators D Yan, HS Cho, CA Hastings, MM Igo, SY Lee, JG Pelton, V Stewart, ... Proceedings of the National Academy of Sciences 96 (26), 14789-14794, 1999 | 191 | 1999 |
Crystal structure of the ternary complex of a NaV C-terminal domain, a fibroblast growth factor homologous factor, and calmodulin C Wang, BC Chung, H Yan, SY Lee, GS Pitt Structure 20 (7), 1167-1176, 2012 | 184 | 2012 |
Two Separate Interfaces between the Voltage Sensor and Pore Are Required for the Function of Voltage-Dependent K+ Channels SY Lee, A Banerjee, R MacKinnon PLoS biology 7 (3), e1000047, 2009 | 180 | 2009 |
NMR structure of activated CheY HS Cho, SY Lee, D Yan, X Pan, JS Parkinson, S Kustu, DE Wemmer, ... Journal of molecular biology 297 (3), 543-551, 2000 | 176 | 2000 |
Heat-dependent opening of TRPV1 in the presence of capsaicin DH Kwon, F Zhang, Y Suo, J Bouvette, MJ Borgnia, SY Lee Nature structural & molecular biology 28 (7), 554-563, 2021 | 165 | 2021 |
GlcNAc-1-P-transferase–tunicamycin complex structure reveals basis for inhibition of N-glycosylation J Yoo, EH Mashalidis, ACY Kuk, K Yamamoto, B Kaeser, S Ichikawa, ... Nature structural & molecular biology 25 (3), 217-224, 2018 | 146 | 2018 |
Detection and characterization of xenon-binding sites in proteins by 129Xe NMR spectroscopy SM Rubin, SY Lee, EJ Ruiz, A Pines, DE Wemmer Journal of molecular biology 322 (2), 425-440, 2002 | 138 | 2002 |
Cryo-EM structure of a mitochondrial calcium uniporter J Yoo, M Wu, Y Yin, MA Herzik Jr, GC Lander, SY Lee Science 361 (6401), 506-511, 2018 | 137 | 2018 |
Cryo-electron microscopy structure of the lysosomal calcium-permeable channel TRPML3 M Hirschi, MA Herzik Jr, J Wie, Y Suo, WF Borschel, D Ren, GC Lander, ... Nature 550 (7676), 411-414, 2017 | 137 | 2017 |
Crystal structure of a concentrative nucleoside transporter from Vibrio cholerae at 2.4 Å ZL Johnson, CG Cheong, SY Lee Nature 483 (7390), 489-493, 2012 | 135 | 2012 |