| Ganglioside GM1 induces phosphorylation of mutant huntingtin and restores normal motor behavior in Huntington disease mice A Di Pardo, V Maglione, M Alpaugh, M Horkey, RS Atwal, J Sassone, ... Proceedings of the National Academy of Sciences 109 (9), 3528-3533, 2012 | 195 | 2012 |
| Demonstration of prion-like properties of mutant huntingtin fibrils in both in vitro and in vivo paradigms M Masnata, G Sciacca, A Maxan, L Bousset, HL Denis, F Lauruol, L David, ... Acta neuropathologica 137, 981-1001, 2019 | 72 | 2019 |
| Disease‐modifying effects of ganglioside GM1 in Huntington's disease models M Alpaugh, D Galleguillos, J Forero, LC Morales, SW Lackey, P Kar, ... EMBO molecular medicine 9 (11), 1537-1557, 2017 | 66 | 2017 |
| N6-Furfuryladenine is protective in Huntington’s disease models by signaling huntingtin phosphorylation LE Bowie, T Maiuri, M Alpaugh, M Gabriel, N Arbez, D Galleguillos, ... Proceedings of the National Academy of Sciences 115 (30), E7081-E7090, 2018 | 52 | 2018 |
| The contribution of inflammatory astrocytes to BBB impairments in a brain-chip model of Parkinson’s disease A de Rus Jacquet, M Alpaugh, HL Denis, JL Tancredi, M Boutin, ... Nature Communications 14 (1), 3651, 2023 | 47 | 2023 |
| Male sex chromosomal complement exacerbates the pathogenicity of Th17 cells in a chronic model of central nervous system autoimmunity PMIA Doss, M Umair, J Baillargeon, R Fazazi, N Fudge, I Akbar, AP Yeola, ... Cell Reports 34 (10), 2021 | 36 | 2021 |
| Shedding a new light on Huntington’s disease: How blood can both propagate and ameliorate disease pathology M Rieux, M Alpaugh, G Sciacca, M Saint-Pierre, M Masnata, HL Denis, ... Molecular psychiatry 26 (9), 5441-5463, 2021 | 35 | 2021 |
| Current and future applications of induced pluripotent stem cell-based models to study pathological proteins in neurodegenerative disorders A de Rus Jacquet, HL Denis, F Cicchetti, M Alpaugh Molecular Psychiatry 26 (7), 2685-2706, 2021 | 33 | 2021 |
| Passive immunization against phosphorylated tau improves features of Huntington's disease pathology M Alpaugh, M Masnata, A de Rus Jacquet, E Lepinay, HL Denis, ... Molecular Therapy 30 (4), 1500-1522, 2022 | 22 | 2022 |
| A light-inducible protein clustering system for in vivo analysis of α-synuclein aggregation in Parkinson disease M Bérard, R Sheta, S Malvaut, R Rodriguez-Aller, M Teixeira, W Idi, ... PLoS Biology 20 (3), e3001578, 2022 | 22 | 2022 |
| A novel wireless brain stimulation device for long-term use in freely moving mice M Alpaugh, M Saint-Pierre, M Dubois, B Aubé, D Arsenault, J Kriz, ... Scientific Reports 9 (1), 6444, 2019 | 20 | 2019 |
| Use of adeno-associated virus-mediated delivery of mutant huntingtin to study the spreading capacity of the protein in mice and non-human primates A Maxan, G Sciacca, M Alpaugh, Z Tao, L Breger, B Dehay, Z Ling, ... Neurobiology of Disease 141, 104951, 2020 | 19 | 2020 |
| Evidence for the spread of human-derived mutant huntingtin protein in mice and non-human primates P Gosset, A Maxan, M Alpaugh, L Breger, B Dehay, Z Tao, Z Ling, C Qin, ... Neurobiology of Disease 141, 104941, 2020 | 18 | 2020 |
| Prion-like properties of the mutant huntingtin protein in living organisms: the evidence and the relevance M Alpaugh, HL Denis, F Cicchetti Molecular psychiatry 27 (1), 269-280, 2022 | 14 | 2022 |
| A brief history of antibody-based therapy M Alpaugh, F Cicchetti Neurobiology of Disease 130, 104504, 2019 | 11 | 2019 |
| Huntington’s disease: lessons from prion disorders M Alpaugh, F Cicchetti Journal of Neurology 268 (9), 3493-3504, 2021 | 8 | 2021 |
| Beneficial effects of cysteamine in Thy1-α-Syn mice and induced pluripotent stem cells with a SNCA gene triplication A Siddu, LS David, N Lauinger, X Chen, M Saint-Pierre, M Alpaugh, ... Neurobiology of disease 145, 105042, 2020 | 8 | 2020 |
| Detection of antibodies against the huntingtin protein in human plasma HL Denis, M Alpaugh, CP Alvarez, A Fenyi, RA Barker, S Chouinard, ... Cellular and Molecular Life Sciences 80 (2), 45, 2023 | 5 | 2023 |
| The troubling story of blood-driven dementias M Rieux, M Alpaugh, F Cicchetti Molecular Psychiatry 24 (2), 162-166, 2019 | 5 | 2019 |
| Cas9 nickase-mediated contraction of CAG/CTG repeats at multiple disease loci A Murillo, M Alpaugh, M Larin, EL Randall, L Heraty, RR Durairaj, ... bioRxiv, 2024.02. 19.580669, 2024 | 3 | 2024 |
