| Association of metformin administration with gut microbiome dysbiosis in healthy volunteers I Elbere, I Kalnina, I Silamikelis, I Konrade, L Zaharenko, K Sekace, ... PloS one 13 (9), e0204317, 2018 | 130 | 2018 |
| Statistical and machine learning techniques in human microbiome studies: contemporary challenges and solutions I Moreno-Indias, L Lahti, M Nedyalkova, I Elbere, G Roshchupkin, ... Frontiers in microbiology 12, 635781, 2021 | 76 | 2021 |
| Epigenetic markers associated with metformin response and intolerance in drug-naïve patients with type 2 diabetes S García-Calzón, A Perfilyev, M Martinell, M Ustinova, S Kalamajski, ... Science translational medicine 12 (561), eaaz1803, 2020 | 58 | 2020 |
| Metformin strongly affects gut microbiome composition in high-fat diet-induced type 2 diabetes mouse model of both sexes L Silamiķele, I Silamiķelis, M Ustinova, Z Kalniņa, I Elbere, R Petrovska, ... Frontiers in Endocrinology 12, 626359, 2021 | 52 | 2021 |
| Baseline gut microbiome composition predicts metformin therapy short-term efficacy in newly diagnosed type 2 diabetes patients I Elbere, I Silamikelis, II Dindune, I Kalnina, M Ustinova, L Zaharenko, ... PLoS One 15 (10), e0241338, 2020 | 50 | 2020 |
| Significantly altered peripheral blood cell DNA methylation profile as a result of immediate effect of metformin use in healthy individuals I Elbere, I Silamikelis, M Ustinova, I Kalnina, L Zaharenko, R Peculis, ... Clinical epigenetics 10, 1-13, 2018 | 40 | 2018 |
| Metformin strongly affects transcriptome of peripheral blood cells in healthy individuals M Ustinova, I Silamikelis, I Kalnina, L Ansone, V Rovite, I Elbere, ... PloS one 14 (11), e0224835, 2019 | 25 | 2019 |
| Novel susceptibility loci identified in a genome-wide association study of type 2 diabetes complications in population of Latvia M Ustinova, R Peculis, R Rescenko, V Rovite, L Zaharenko, I Elbere, ... BMC Medical Genomics 14, 1-11, 2021 | 23 | 2021 |
| Whole-blood transcriptome profiling reveals signatures of metformin and its therapeutic response M Ustinova, L Ansone, I Silamikelis, V Rovite, I Elbere, L Silamikele, ... PLoS One 15 (8), e0237400, 2020 | 23 | 2020 |
| Next-generation-sequencing-based identification of familial hypercholesterolemia-related mutations in subjects with increased LDL–C levels in a latvian population I Radovica-Spalvina, G Latkovskis, I Silamikelis, D Fridmanis, I Elbere, ... BMC medical genetics 16, 1-9, 2015 | 23 | 2015 |
| A widely used sampling device in colorectal cancer screening programmes allows for large-scale microbiome studies D Gudra, S Shoaie, D Fridmanis, J Klovins, H Wefer, I Silamikelis, ... Gut 68 (9), 1723-1725, 2019 | 22 | 2019 |
| Metformin targets intestinal immune system signaling pathways in a high-fat diet-induced mouse model of obesity and insulin resistance M Brīvība, L Silamiķele, I Kalniņa, I Silamiķelis, L Birzniece, L Ansone, ... Frontiers in Endocrinology 14, 1232143, 2023 | 7 | 2023 |
| Kalnin, a, I I Elbere, R Petrovska Klovin, š, J. Metformin Strongly Affects Gut Microbiome Composition in High …, 0 | 7 | |
| Gut microbiome composition and dynamics in hospitalized covid-19 patients and patients with post-acute covid-19 syndrome M Brīvība, L Silamiķele, L Birzniece, L Ansone, K Megnis, I Silamiķelis, ... International Journal of Molecular Sciences 25 (1), 567, 2024 | 6 | 2024 |
| Epigenetic markers associated with metformin response and intolerance in drug-naïve patients with type 2 diabetes. Sci Transl Med. 2020 S García-Calzón, A Perfilyev, M Martinell, M Ustinova, S Kalamajski, ... | 5 | |
| Metatranscriptome analysis of blood in healthy individuals and irritable bowel syndrome patients L Jagare, M Rozenberga, I Silamikelis, L Ansone, I Elbere, M Briviba, ... Journal of Medical Microbiology 72 (6), 001719, 2023 | 3 | 2023 |
| Gut microbiome encoded purine and amino acid pathways present prospective biomarkers for predicting metformin therapy efficacy in newly diagnosed T2D patients I Elbere, Z Orlovskis, L Ansone, I Silamikelis, L Jagare, L Birzniece, ... Gut Microbes 16 (1), 2361491, 2024 | 2 | 2024 |
| Evaluating the Efficacy of Type 2 Diabetes Polygenic Risk Scores in an Independent European Population M Brīvība, I Atava, R Pečulis, I Elbere, L Ansone, M Rozenberga, ... International Journal of Molecular Sciences 25 (2), 1151, 2024 | 2 | 2024 |
| Changes in the gut mycobiome are associated with Type 2 diabetes mellitus and metformin treatment across populations EV Syoc, MP Nixon, JD Silverman, Y Luo, FJ Gonzalez, I Elbere, J Klovins, ... bioRxiv, 2023.05. 25.542255, 2023 | 2 | 2023 |
| Identification of the composition, stability, and origin of blood microbiome in humans M Rozenberga, R Saksis, I Elbere, L Birzniece, M Briviba, I Konrade, ... | 2 | 2022 |
