Safety and immunogenicity of an anti-Middle East respiratory syndrome coronavirus DNA vaccine: a phase 1, open-label, single-arm, dose-escalation trial K Modjarrad, CC Roberts, KT Mills, AR Castellano, K Paolino, ... The Lancet Infectious Diseases 19 (9), 1013-1022, 2019 | 346 | 2019 |
Lipid bodies containing oxidatively truncated lipids block antigen cross-presentation by dendritic cells in cancer F Veglia, VA Tyurin, D Mohammadyani, M Blasi, EK Duperret, ... Nature communications 8 (1), 2122, 2017 | 266 | 2017 |
In vivo protection against ZIKV infection and pathogenesis through passive antibody transfer and active immunisation with a prMEnv DNA vaccine K Muthumani, BD Griffin, S Agarwal, SB Kudchodkar, EL Reuschel, ... npj Vaccines 1 (1), 1-11, 2016 | 147 | 2016 |
Sex steroids regulate skin pigmentation through nonclassical membrane-bound receptors CA Natale, EK Duperret, J Zhang, R Sadeghi, A Dahal, KT O'Brien, ... Elife 5, e15104, 2016 | 138 | 2016 |
Alteration of the tumor stroma using a consensus DNA vaccine targeting fibroblast activation protein (FAP) synergizes with antitumor vaccine therapy in mice EK Duperret, A Trautz, D Ammons, A Perales-Puchalt, MC Wise, J Yan, ... Clinical Cancer Research 24 (5), 1190-1201, 2018 | 133 | 2018 |
A Synthetic DNA, Multi-Neoantigen Vaccine Drives Predominately MHC Class I CD8+ T-cell Responses, Impacting Tumor Challenge EK Duperret, A Perales-Puchalt, R Stoltz, H GH, N Mandloi, J Barlow, ... Cancer immunology research 7 (2), 174-182, 2019 | 106 | 2019 |
CDKN2B Loss Promotes Progression from Benign Melanocytic Nevus to Melanoma AS McNeal, K Liu, V Nakhate, CA Natale, EK Duperret, BC Capell, ... Cancer discovery 5 (10), 1072-1085, 2015 | 105 | 2015 |
Enhanced antitumor immunity by a novel small molecule HPK1 inhibitor D You, S Hillerman, G Locke, C Chaudhry, C Stromko, A Murtaza, Y Fan, ... Journal for ImmunoTherapy of Cancer 9 (1), 2021 | 70 | 2021 |
Focal-adhesion-independent integrin-αv regulation of FAK and c-Myc is necessary for 3D skin formation and tumor invasion EK Duperret, A Dahal, TW Ridky Journal of cell science 128 (21), 3997-4013, 2015 | 62 | 2015 |
Synthetic DNA-Encoded Monoclonal Antibody Delivery of Anti–CTLA-4 Antibodies Induces Tumor Shrinkage In Vivo EK Duperret, A Trautz, R Stoltz, A Patel, MC Wise, A Perales-Puchalt, ... Cancer research 78 (22), 6363-6370, 2018 | 54 | 2018 |
Synergy of immune checkpoint blockade with a novel synthetic consensus DNA vaccine targeting TERT EK Duperret, MC Wise, A Trautz, DO Villarreal, B Ferraro, J Walters, J Yan, ... Molecular Therapy 26 (2), 435-445, 2018 | 46 | 2018 |
Novel prostate cancer immunotherapy with a DNA-encoded anti-prostate-specific membrane antigen monoclonal antibody K Muthumani, L Marnin, SB Kudchodkar, A Perales-Puchalt, H Choi, ... Cancer Immunology, Immunotherapy 66, 1577-1588, 2017 | 45 | 2017 |
A designer cross-reactive DNA immunotherapeutic vaccine that targets multiple MAGE-A family members simultaneously for cancer therapy EK Duperret, S Liu, M Paik, A Trautz, R Stoltz, X Liu, K Ze, ... Clinical Cancer Research 24 (23), 6015-6027, 2018 | 44 | 2018 |
Activating FGFR3 mutations cause mild hyperplasia in human skin, but are insufficient to drive benign or malignant skin tumors EK Duperret, SJ Oh, A McNeal, SM Prouty, TW Ridky Cell Cycle 13 (10), 1551-1559, 2014 | 43 | 2014 |
DNA-encoded bispecific T cell engagers and antibodies present long-term antitumor activity A Perales-Puchalt, EK Duperret, X Yang, P Hernandez, K Wojtak, X Zhu, ... JCI insight 4 (8), 2019 | 42 | 2019 |
IQGAP1 and IQGAP3 serve individually essential roles in normal epidermal homeostasis and tumor progression CL Monteleon, A McNeal, EK Duperret, SJ Oh, E Schapira, TW Ridky Journal of Investigative Dermatology 135 (9), 2258-2265, 2015 | 42 | 2015 |
Focal adhesion complex proteins in epidermis and squamous cell carcinoma E Duperret, TW Ridky Cell cycle 12 (20), 3272-3285, 2013 | 40 | 2013 |
A novel DNA vaccine platform enhances neo-antigen-like T cell responses against WT1 to break tolerance and induce anti-tumor immunity JN Walters, B Ferraro, EK Duperret, KA Kraynyak, J Chu, A Saint-Fleur, ... Molecular Therapy 25 (4), 976-988, 2017 | 34 | 2017 |
The integrin αv-TGFβ signaling axis is necessary for epidermal proliferation during cutaneous wound healing EK Duperret, CA Natale, C Monteleon, A Dahal, TW Ridky Cell Cycle 15 (15), 2077-2086, 2016 | 34 | 2016 |
Engineered DNA vaccination against follicle-stimulating hormone receptor delays ovarian cancer progression in animal models A Perales-Puchalt, K Wojtak, EK Duperret, X Yang, AM Slager, J Yan, ... Molecular Therapy 27 (2), 314-325, 2019 | 30 | 2019 |