6α-ethyl-chenodeoxycholic acid (6-ECDCA), a potent and selective FXR agonist endowed with anticholestatic activity R Pellicciari, S Fiorucci, E Camaioni, C Clerici, G Costantino, PR Maloney, ... Journal of medicinal chemistry 45 (17), 3569-3572, 2002 | 901 | 2002 |
ADP receptors of platelets and their inhibition C Gachet Thrombosis and haemostasis 86 (07), 222-232, 2001 | 583 | 2001 |
Adenosine deaminase: functional implications and different classes of inhibitors G Cristalli, S Costanzi, C Lambertucci, G Lupidi, S Vittori, R Volpini, ... Medicinal research reviews 21 (2), 105-128, 2001 | 461 | 2001 |
Bile acid derivatives as ligands of the farnesoid X receptor. Synthesis, evaluation, and structure− activity relationship of a series of body and side chain modified analogues … R Pellicciari, G Costantino, E Camaioni, BM Sadeghpour, A Entrena, ... Journal of medicinal chemistry 47 (18), 4559-4569, 2004 | 258 | 2004 |
Competitive and selective antagonism of P2Y1 receptors by N6‐methyl 2′‐deoxyadenosine 3′,5′‐bisphosphate JL Boyer, A Mohanram, E Camaioni, KA Jacobson, TK Harden British journal of pharmacology 124 (1), 1-3, 1998 | 238 | 1998 |
Human P2Y1 Receptor: Molecular Modeling and Site-Directed Mutagenesis as Tools To Identify Agonist and Antagonist Recognition Sites S Moro, D Guo, E Camaioni, JL Boyer, TK Harden, KA Jacobson Journal of medicinal chemistry 41 (9), 1456-1466, 1998 | 199 | 1998 |
Modeling of poly (ADP-ribose) polymerase (PARP) inhibitors. Docking of ligands and quantitative structure− activity relationship analysis G Costantino, A Macchiarulo, E Camaioni, R Pellicciari Journal of medicinal chemistry 44 (23), 3786-3794, 2001 | 165 | 2001 |
Deoxyadenosine bisphosphate derivatives as potent antagonists at P2Y1 receptors E Camaioni, JL Boyer, A Mohanram, TK Harden, KA Jacobson Journal of medicinal chemistry 41 (2), 183-190, 1998 | 165 | 1998 |
Highlights at the gate of tryptophan catabolism: a review on the mechanisms of activation and regulation of indoleamine 2, 3-dioxygenase (IDO), a novel target in cancer disease A Macchiarulo, E Camaioni, R Nuti, R Pellicciari Amino acids 37, 219-229, 2009 | 152 | 2009 |
Recent advances in urea-and thiourea-containing compounds: focus on innovative approaches in medicinal chemistry and organic synthesis R Ronchetti, G Moroni, A Carotti, A Gioiello, E Camaioni RSC medicinal chemistry 12 (7), 1046-1064, 2021 | 137 | 2021 |
Poly (ADP-ribose) catabolism triggers AMP-dependent mitochondrial energy failure L Formentini, A Macchiarulo, G Cipriani, E Camaioni, E Rapizzi, ... Journal of Biological Chemistry 284 (26), 17668-17676, 2009 | 116 | 2009 |
New substituted 9-alkylpurines as adenosine receptor ligands E Camaioni, S Costanzi, S Vittori, R Volpini, KN Klotz, G Cristalli Bioorganic & medicinal chemistry 6 (5), 523-533, 1998 | 116 | 1998 |
2-Alkynyl derivatives of adenosine-5'-N-ethyluronamide: selective A2 adenosine receptor agonists with potent inhibitory activity on platelet aggregation G Cristalli, R Volpini, S Vittori, E Camaioni, A Monopoli, A Conti, ... Journal of medicinal chemistry 37 (11), 1720-1726, 1994 | 106 | 1994 |
2-Aralkynyl and 2-heteroalkynyl derivatives of adenosine-5'-N-ethyluronamide as selective A2a adenosine receptor agonists G Cristalli, E Camaioni, S Vittori, R Volpini, PA Borea, A Conti, S Dionisotti, ... Journal of medicinal chemistry 38 (9), 1462-1472, 1995 | 100 | 1995 |
Synthesis and biological evaluation of 2-(3′-(1H-tetrazol-5-yl) bicyclo [1.1. 1] pent-1-yl) glycine (S-TBPG), a novel mGlu1 receptor antagonist G Costantino, K Maltoni, M Marinozzi, E Camaioni, L Prezeau, JP Pin, ... Bioorganic & medicinal chemistry 9 (2), 221-227, 2001 | 98 | 2001 |
PARP inhibitors: polypharmacology versus selective inhibition T Ekblad, E Camaioni, H Schüler, A Macchiarulo The FEBS journal 280 (15), 3563-3575, 2013 | 92 | 2013 |
2-Substituted N-ethylcarboxamidoadenosine derivatives as high-affinity agonists at human A3 adenosine receptors KN Klotz, E Camaioni, R Volpini, S Kachler, S Vittori, G Cristalli Naunyn-Schmiedeberg's archives of pharmacology 360, 103-108, 1999 | 90 | 1999 |
Novel isoquinolinone-derived inhibitors of poly (ADP-ribose) polymerase-1: pharmacological characterization and neuroprotective effects in an in vitro model of cerebral ischemia A Chiarugi, E Meli, M Calvani, R Picca, R Baronti, E Camaioni, ... Journal of Pharmacology and Experimental Therapeutics 305 (3), 943-949, 2003 | 88 | 2003 |
On the way to selective PARP‐2 inhibitors. Design, synthesis, and preliminary evaluation of a series of isoquinolinone derivatives R Pellicciari, E Camaioni, G Costantino, L Formentini, P Sabbatini, ... ChemMedChem: Chemistry Enabling Drug Discovery 3 (6), 914-923, 2008 | 86 | 2008 |
Rat brain guanosine binding site: Biological studies and pseudo-receptor construction U Traversa, G Bombi, E Camaioni, A Macchiarulo, G Costantino, ... Bioorganic & medicinal chemistry 11 (24), 5417-5425, 2003 | 80 | 2003 |