| Mapping the human genetic architecture of COVID-19 Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ... Nature 600 (7889), 472-477, 2021 | 843 | 2021 |
| Swarm learning for decentralized and confidential clinical machine learning S Warnat-Herresthal, H Schultze, KL Shastry, S Manamohan, ... Nature 594 (7862), 265-270, 2021 | 747 | 2021 |
| Increased tryptophan metabolism is associated with activity of inflammatory bowel diseases S Nikolaus, B Schulte, N Al-Massad, F Thieme, DM Schulte, J Bethge, ... Gastroenterology 153 (6), 1504-1516. e2, 2017 | 506 | 2017 |
| Immunogenicity and safety of anti-SARS-CoV-2 mRNA vaccines in patients with chronic inflammatory conditions and immunosuppressive therapy in a monocentric cohort UM Geisen, DK Berner, F Tran, M Sümbül, L Vullriede, M Ciripoi, HM Reid, ... Annals of the rheumatic diseases 80 (10), 1306-1311, 2021 | 391 | 2021 |
| Longitudinal multi-omics analyses identify responses of megakaryocytes, erythroid cells, and plasmablasts as hallmarks of severe COVID-19 JP Bernardes, N Mishra, F Tran, T Bahmer, L Best, JI Blase, D Bordoni, ... Immunity 53 (6), 1296-1314. e9, 2020 | 339 | 2020 |
| Low-avidity CD4+ T cell responses to SARS-CoV-2 in unexposed individuals and humans with severe COVID-19 P Bacher, E Rosati, D Esser, GR Martini, C Saggau, E Schiminsky, ... Immunity 53 (6), 1258-1271. e5, 2020 | 306 | 2020 |
| Therapeutic interleukin-6 trans-signaling inhibition by olamkicept (sgp130Fc) in patients with active inflammatory bowel disease S Schreiber, K Aden, JP Bernardes, C Conrad, F Tran, H Höper, V Volk, ... Gastroenterology 160 (7), 2354-2366. e11, 2021 | 198 | 2021 |
| ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS–STING K Aden, F Tran, GO Ito, R Sheibani-Tezerji, S Lipinski, JW Kuiper, ... Journal of Experimental Medicine 215 (11), 2868-2886, 2018 | 153 | 2018 |
| Autoantibodies targeting GPCRs and RAS-related molecules associate with COVID-19 severity O Cabral-Marques, G Halpert, LF Schimke, Y Ostrinski, A Vojdani, ... Nature communications 13 (1), 1220, 2022 | 119 | 2022 |
| Activating transcription factor 6 mediates inflammatory signals in intestinal epithelial cells upon endoplasmic reticulum stress ST Stengel, A Fazio, S Lipinski, MT Jahn, K Aden, G Ito, F Wottawa, ... Gastroenterology 159 (4), 1357-1374. e10, 2020 | 108 | 2020 |
| Epithelial IL-23R signaling licenses protective IL-22 responses in intestinal inflammation K Aden, A Rehman, M Falk-Paulsen, T Secher, J Kuiper, F Tran, ... Cell reports 16 (8), 2208-2218, 2016 | 107 | 2016 |
| Radiotherapy orchestrates natural killer cell dependent antitumor immune responses through CXCL8 T Walle, JA Kraske, B Liao, B Lenoir, C Timke, E von Bohlen und Halbach, ... Science advances 8 (12), eabh4050, 2022 | 100 | 2022 |
| Detailed stratified GWAS analysis for severe COVID-19 in four European populations F Degenhardt, D Ellinghaus, S Juzenas, J Lerga-Jaso, M Wendorff, ... Human molecular genetics 31 (23), 3945-3966, 2022 | 91* | 2022 |
| Epithelial RNase H2 maintains genome integrity and prevents intestinal tumorigenesis in mice K Aden, K Bartsch, J Dahl, MAM Reijns, D Esser, R Sheibani-Tezerji, ... Gastroenterology 156 (1), 145-159. e19, 2019 | 61 | 2019 |
| A novel unconventional T cell population enriched in Crohn’s disease E Rosati, GR Martini, MV Pogorelyy, AA Minervina, F Degenhardt, ... Gut 71 (11), 2194-2204, 2022 | 50 | 2022 |
| A second update on mapping the human genetic architecture of COVID-19 M Kanai, SJ Andrews, M Cordioli, C Stevens, BM Neale, M Daly, A Ganna, ... Nature 621 (7977), E7-E26, 2023 | 49 | 2023 |
| Circulating levels of soluble Dipeptidylpeptidase-4 are reduced in human subjects hospitalized for severe COVID-19 infections K Schlicht, N Rohmann, C Geisler, T Hollstein, C Knappe, K Hartmann, ... International journal of obesity 44 (11), 2335-2338, 2020 | 40 | 2020 |
| Humoral protection to SARS-CoV2 declines faster in patients on TNF alpha blocking therapies UM Geisen, M Sümbül, F Tran, DK Berner, HM Reid, L Vullriede, M Ciripoi, ... RMD open 7 (3), e002008, 2021 | 39 | 2021 |
| Longitudinal multi-omics analysis identifies early blood-based predictors of anti-TNF therapy response in inflammatory bowel disease N Mishra, K Aden, JI Blase, N Baran, D Bordoni, F Tran, C Conrad, ... Genome medicine 14 (1), 110, 2022 | 38 | 2022 |
| Leptin induces TNFα-dependent inflammation in acquired generalized lipodystrophy and combined Crohn’s disease JF Ziegler, C Böttcher, M Letizia, C Yerinde, H Wu, I Freise, ... Nature communications 10 (1), 5629, 2019 | 37 | 2019 |
