Metabolism, biochemical actions, and chemical synthesis of anticancer nucleosides, nucleotides, and base analogs J Shelton, X Lu, JA Hollenbaugh, JH Cho, F Amblard, RF Schinazi Chemical reviews 116 (23), 14379-14455, 2016 | 405 | 2016 |
Chutes and ladders in hepatitis C nucleoside drug development SJ Coats, EC Garnier-Amblard, F Amblard, M Ehteshami, S Amiralaei, ... Antiviral research 102, 119-147, 2014 | 80 | 2014 |
Substrates and Inhibitors of SAMHD1 JA Hollenbaugh, J Shelton, S Tao, S Amiralaei, P Liu, X Lu, RW Goetze, ... PloS one 12 (1), e0169052, 2017 | 54 | 2017 |
The design and synthesis of N-1-alkylated-5-aminoaryalkylsubstituted-6-methyluracils as potential non-nucleoside HIV-1 RT inhibitors X Lu, Y Chen, Y Guo, Z Liu, Y Shi, Y Xu, X Wang, Z Zhang, J Liu Bioorganic & medicinal chemistry 15 (23), 7399-7407, 2007 | 49 | 2007 |
Phosphonium lipocations as antiparasitic agents TE Long, X Lu, M Galizzi, R Docampo, J Gut, PJ Rosenthal Bioorganic & medicinal chemistry letters 22 (8), 2976-2979, 2012 | 41 | 2012 |
1, 4-Naphthoquinone cations as antiplasmodial agents: hydroxy-, acyloxy-, and alkoxy-substituted analogues X Lu, A Altharawi, J Gut, PJ Rosenthal, TE Long ACS Medicinal Chemistry Letters 3 (12), 1029-1033, 2012 | 34 | 2012 |
Torin 2 Derivative, NCATS-SM3710, Has Potent Multistage Antimalarial Activity through Inhibition of P. falciparum Phosphatidylinositol 4-Kinase (Pf PI4KIIIβ) K Krishnan, P Ziniel, H Li, X Huang, D Hupalo, N Gombakomba, ... ACS Pharmacology & Translational Science 3 (5), 948-964, 2020 | 22 | 2020 |
Synthesis and antiviral evaluation of novel heteroarylpyrimidines analogs as HBV capsid effectors S Boucle, X Lu, L Bassit, T Ozturk, OO Russell, F Amblard, SJ Coats, ... Bioorganic & medicinal chemistry letters 27 (4), 904-910, 2017 | 19 | 2017 |
Asymmetric synthesis of monocyclic β-lactams from l-cysteine using photochemistry X Lu, TE Long Tetrahedron letters 52 (39), 5051-5054, 2011 | 19 | 2011 |
Application of niclosamide and analogs as small molecule inhibitors of Zika virus and SARS-CoV-2 infection K Shamim, M Xu, X Hu, EM Lee, X Lu, R Huang, P Shah, X Xu, CZ Chen, ... Bioorganic & Medicinal Chemistry Letters 40, 127906, 2021 | 18 | 2021 |
Discovery, characterization, and lead optimization of 7-azaindole non-nucleoside HIV-1 reverse transcriptase inhibitors RA Stanton, X Lu, M Detorio, C Montero, ET Hammond, M Ehteshami, ... Bioorganic & medicinal chemistry letters 26 (16), 4101-4105, 2016 | 18 | 2016 |
o-Nitrophenyl Sulfoxides: Efficient Precursors for the Mild Preparation of Alkenes X Lu, TE Long The Journal of Organic Chemistry 75 (1), 249-252, 2010 | 15 | 2010 |
Biochemical characterization of the active anti-hepatitis C virus metabolites of 2, 6-diaminopurine ribonucleoside prodrug compared to sofosbuvir and BMS-986094 M Ehteshami, S Tao, T Ozturk, L Zhou, JH Cho, H Zhang, S Amiralaei, ... Antimicrobial agents and chemotherapy 60 (8), 4659-4669, 2016 | 13 | 2016 |
Efficient Synthesis of 1,9-Substituted Benzo[h][1,6]naphthyridin-2(1H)-ones and Evaluation of their Plasmodium falciparum Gametocytocidal Activities H Li, W Sun, X Huang, X Lu, PR Patel, M Kim, MJ Orr, RM Fisher, ... ACS combinatorial science 19 (12), 748-754, 2017 | 11 | 2017 |
Nucleotide substrate specificity of anti-hepatitis C virus nucleoside analogs for human mitochondrial RNA polymerase M Ehteshami, L Zhou, S Amiralaei, JR Shelton, JH Cho, H Zhang, H Li, ... Antimicrobial agents and chemotherapy 61 (8), 10.1128/aac. 00492-17, 2017 | 11 | 2017 |
Haloenol pyranones and morpholinones as antineoplastic agents of prostate cancer JN Mock, JP Taliaferro, X Lu, SK Patel, BS Cummings, TE Long Bioorganic & medicinal chemistry letters 22 (14), 4854-4858, 2012 | 9 | 2012 |
Phase-transfer catalysts in the O-alkylation of 2-hydroxynaphthoquinones X Lu, A Altharawi, EN Hansen, TE Long Synthesis 44 (20), 3225-3230, 2012 | 6 | 2012 |
Acid‐Promoted Cascade Reaction of N‐(4‐Chloroquinolin‐3‐yl)carbamates with Amines: One‐Pot Assembly of Imidazo[4,5‐c]quinolin‐2‐ones X Lu, M Kim, MJ Orr, H Li, W Huang European journal of organic chemistry 2018 (13), 1572-1580, 2018 | 2 | 2018 |
Compounds and method for blocking transmission of malarial parasite W Huang, H Li, W Sun, X Huang, PR Patel, H Sun, W Zheng, X Lu, ... WO Patent WO/2018/071,836, 2018 | 2 | 2018 |
High‐Throughput Platform for Novel Reaction Discovery X Lu, Z Luo, R Huang, DC Lo, W Huang Chemistry–A European Journal 28 (50), e202201421, 2022 | 1 | 2022 |