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Xiao Lu
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Metabolism, biochemical actions, and chemical synthesis of anticancer nucleosides, nucleotides, and base analogs
J Shelton, X Lu, JA Hollenbaugh, JH Cho, F Amblard, RF Schinazi
Chemical reviews 116 (23), 14379-14455, 2016
4052016
Chutes and ladders in hepatitis C nucleoside drug development
SJ Coats, EC Garnier-Amblard, F Amblard, M Ehteshami, S Amiralaei, ...
Antiviral research 102, 119-147, 2014
802014
Substrates and Inhibitors of SAMHD1
JA Hollenbaugh, J Shelton, S Tao, S Amiralaei, P Liu, X Lu, RW Goetze, ...
PloS one 12 (1), e0169052, 2017
542017
The design and synthesis of N-1-alkylated-5-aminoaryalkylsubstituted-6-methyluracils as potential non-nucleoside HIV-1 RT inhibitors
X Lu, Y Chen, Y Guo, Z Liu, Y Shi, Y Xu, X Wang, Z Zhang, J Liu
Bioorganic & medicinal chemistry 15 (23), 7399-7407, 2007
492007
Phosphonium lipocations as antiparasitic agents
TE Long, X Lu, M Galizzi, R Docampo, J Gut, PJ Rosenthal
Bioorganic & medicinal chemistry letters 22 (8), 2976-2979, 2012
412012
1, 4-Naphthoquinone cations as antiplasmodial agents: hydroxy-, acyloxy-, and alkoxy-substituted analogues
X Lu, A Altharawi, J Gut, PJ Rosenthal, TE Long
ACS Medicinal Chemistry Letters 3 (12), 1029-1033, 2012
342012
Torin 2 Derivative, NCATS-SM3710, Has Potent Multistage Antimalarial Activity through Inhibition of P. falciparum Phosphatidylinositol 4-Kinase (Pf PI4KIIIβ)
K Krishnan, P Ziniel, H Li, X Huang, D Hupalo, N Gombakomba, ...
ACS Pharmacology & Translational Science 3 (5), 948-964, 2020
222020
Synthesis and antiviral evaluation of novel heteroarylpyrimidines analogs as HBV capsid effectors
S Boucle, X Lu, L Bassit, T Ozturk, OO Russell, F Amblard, SJ Coats, ...
Bioorganic & medicinal chemistry letters 27 (4), 904-910, 2017
192017
Asymmetric synthesis of monocyclic β-lactams from l-cysteine using photochemistry
X Lu, TE Long
Tetrahedron letters 52 (39), 5051-5054, 2011
192011
Application of niclosamide and analogs as small molecule inhibitors of Zika virus and SARS-CoV-2 infection
K Shamim, M Xu, X Hu, EM Lee, X Lu, R Huang, P Shah, X Xu, CZ Chen, ...
Bioorganic & Medicinal Chemistry Letters 40, 127906, 2021
182021
Discovery, characterization, and lead optimization of 7-azaindole non-nucleoside HIV-1 reverse transcriptase inhibitors
RA Stanton, X Lu, M Detorio, C Montero, ET Hammond, M Ehteshami, ...
Bioorganic & medicinal chemistry letters 26 (16), 4101-4105, 2016
182016
o-Nitrophenyl Sulfoxides: Efficient Precursors for the Mild Preparation of Alkenes
X Lu, TE Long
The Journal of Organic Chemistry 75 (1), 249-252, 2010
152010
Biochemical characterization of the active anti-hepatitis C virus metabolites of 2, 6-diaminopurine ribonucleoside prodrug compared to sofosbuvir and BMS-986094
M Ehteshami, S Tao, T Ozturk, L Zhou, JH Cho, H Zhang, S Amiralaei, ...
Antimicrobial agents and chemotherapy 60 (8), 4659-4669, 2016
132016
Efficient Synthesis of 1,9-Substituted Benzo[h][1,6]naphthyridin-2(1H)-ones and Evaluation of their Plasmodium falciparum Gametocytocidal Activities
H Li, W Sun, X Huang, X Lu, PR Patel, M Kim, MJ Orr, RM Fisher, ...
ACS combinatorial science 19 (12), 748-754, 2017
112017
Nucleotide substrate specificity of anti-hepatitis C virus nucleoside analogs for human mitochondrial RNA polymerase
M Ehteshami, L Zhou, S Amiralaei, JR Shelton, JH Cho, H Zhang, H Li, ...
Antimicrobial agents and chemotherapy 61 (8), 10.1128/aac. 00492-17, 2017
112017
Haloenol pyranones and morpholinones as antineoplastic agents of prostate cancer
JN Mock, JP Taliaferro, X Lu, SK Patel, BS Cummings, TE Long
Bioorganic & medicinal chemistry letters 22 (14), 4854-4858, 2012
92012
Phase-transfer catalysts in the O-alkylation of 2-hydroxynaphthoquinones
X Lu, A Altharawi, EN Hansen, TE Long
Synthesis 44 (20), 3225-3230, 2012
62012
Acid‐Promoted Cascade Reaction of N‐(4‐Chloroquinolin‐3‐yl)carbamates with Amines: One‐Pot Assembly of Imidazo[4,5‐c]quinolin‐2‐ones
X Lu, M Kim, MJ Orr, H Li, W Huang
European journal of organic chemistry 2018 (13), 1572-1580, 2018
22018
Compounds and method for blocking transmission of malarial parasite
W Huang, H Li, W Sun, X Huang, PR Patel, H Sun, W Zheng, X Lu, ...
WO Patent WO/2018/071,836, 2018
22018
High‐Throughput Platform for Novel Reaction Discovery
X Lu, Z Luo, R Huang, DC Lo, W Huang
Chemistry–A European Journal 28 (50), e202201421, 2022
12022
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Articles 1–20