| Phase transition in postsynaptic densities underlies formation of synaptic complexes and synaptic plasticity M Zeng, Y Shang, Y Araki, T Guo, RL Huganir, M Zhang Cell 166 (5), 1163-1175. e12, 2016 | 549 | 2016 |
| Excess of de novo deleterious mutations in genes associated with glutamatergic systems in nonsyndromic intellectual disability FF Hamdan, J Gauthier, Y Araki, DT Lin, Y Yoshizawa, K Higashi, AR Park, ... The American Journal of Human Genetics 88 (3), 306-316, 2011 | 428 | 2011 |
| Rapid dispersion of SynGAP from synaptic spines triggers AMPA receptor insertion and spine enlargement during LTP Y Araki, M Zeng, M Zhang, RL Huganir Neuron 85 (1), 173-189, 2015 | 285 | 2015 |
| Mitochondrial stasis reveals p62-mediated ubiquitination in parkin-independent mitophagy and mitigates nonalcoholic fatty liver disease T Yamada, D Murata, Y Adachi, K Itoh, S Kameoka, A Igarashi, T Kato, ... Cell metabolism 28 (4), 588-604. e5, 2018 | 246 | 2018 |
| Novel cadherin-related membrane proteins, Alcadeins, enhance the X11-like protein-mediated stabilization of amyloid β-protein precursor metabolism Y Araki, S Tomita, H Yamaguchi, N Miyagi, A Sumioka, Y Kirino, T Suzuki Journal of Biological Chemistry 278 (49), 49448-49458, 2003 | 183 | 2003 |
| The novel cargo Alcadein induces vesicle association of kinesin‐1 motor components and activates axonal transport Y Araki, T Kawano, H Taru, Y Saito, S Wada, K Miyamoto, H Kobayashi, ... The EMBO journal 26 (6), 1475-1486, 2007 | 180 | 2007 |
| Twenty years of SynGAP research: from synapses to cognition TR Gamache, Y Araki, RL Huganir Journal of Neuroscience 40 (8), 1596-1605, 2020 | 150 | 2020 |
| Plasma membrane insertion of the AMPA receptor GluA2 subunit is regulated by NSF binding and Q/R editing of the ion pore Y Araki, DT Lin, RL Huganir Proceedings of the National Academy of Sciences 107 (24), 11080-11085, 2010 | 121 | 2010 |
| PAKs inhibitors ameliorate schizophrenia-associated dendritic spine deterioration in vitro and in vivo during late adolescence A Hayashi-Takagi, Y Araki, M Nakamura, B Vollrath, SG Duron, Z Yan, ... Proceedings of the National Academy of Sciences 111 (17), 6461-6466, 2014 | 117 | 2014 |
| Coordinated metabolism of Alcadein and amyloid β-protein precursor regulates FE65-dependent gene transactivation Y Araki, N Miyagi, N Kato, T Yoshida, S Wada, M Nishimura, H Komano, ... Journal of Biological Chemistry 279 (23), 24343-24354, 2004 | 115 | 2004 |
| SynGAP isoforms differentially regulate synaptic plasticity and dendritic development Y Araki, I Hong, TR Gamache, S Ju, L Collado-Torres, JH Shin, ... Elife 9, e56273, 2020 | 92 | 2020 |
| Trafficking of Alzheimer's Disease–Related Membrane Proteins and Its Participation in Disease Pathogenesis T Suzuki, Y Araki, T Yamamoto, T Nakaya Journal of biochemistry 139 (6), 949-955, 2006 | 74 | 2006 |
| Quantitative analysis of APP axonal transport in neurons: role of JIP1 in enhanced APP anterograde transport K Chiba, M Araseki, K Nozawa, K Furukori, Y Araki, T Matsushima, ... Molecular biology of the cell 25 (22), 3569-3580, 2014 | 70 | 2014 |
| A Small Peptide Sequence is Sufficient for Initiating Kinesin‐1 Activation Through Part of TPR Region of KLC1 T Kawano, M Araseki, Y Araki, M Kinjo, T Yamamoto, T Suzuki Traffic 13 (6), 834-848, 2012 | 61 | 2012 |
| Alternative processing of γ‐secretase substrates in common forms of mild cognitive impairment and Alzheimer's disease: evidence for γ‐secretase dysfunction S Hata, S Fujishige, Y Araki, M Taniguchi, K Urakami, E Peskind, ... Annals of neurology 69 (6), 1026-1031, 2011 | 52 | 2011 |
| Alcadein cleavages by amyloid β-precursor protein (APP) α-and γ-secretases generate small peptides, p3-Alcs, indicating Alzheimer disease-related γ-secretase dysfunction S Hata, S Fujishige, Y Araki, N Kato, M Araseki, M Nishimura, D Hartmann, ... Journal of Biological Chemistry 284 (52), 36024-36033, 2009 | 50 | 2009 |
| Low-dose perampanel rescues cortical gamma dysregulation associated with parvalbumin interneuron GluA2 upregulation in epileptic Syngap1+/− mice BJ Sullivan, S Ammanuel, PA Kipnis, Y Araki, RL Huganir, SD Kadam Biological psychiatry 87 (9), 829-842, 2020 | 45 | 2020 |
| Brain-specific Drp1 regulates postsynaptic endocytosis and dendrite formation independently of mitochondrial division K Itoh, D Murata, T Kato, T Yamada, Y Araki, A Saito, Y Adachi, A Igarashi, ... Elife 8, e44739, 2019 | 41 | 2019 |
| Intracellular trafficking of the amyloid β-protein precursor (APP) regulated by novel function of X11-like Y Saito, M Akiyama, Y Araki, A Sumioka, M Shiono, H Taru, T Nakaya, ... PloS one 6 (7), e22108, 2011 | 41 | 2011 |
| SynGAP splice variants display heterogeneous spatio‐temporal expression and subcellular distribution in the developing mammalian brain G Gou, A Roca‐Fernandez, M Kilinc, E Serrano, R Reig‐Viader, Y Araki, ... Journal of neurochemistry 154 (6), 618-634, 2020 | 38 | 2020 |
Richard L HuganirProfessor of Neuroscience, Johns Hopkins University School of MedicineVerified email at jhmi.edu