| Guidelines for the use and interpretation of assays for monitoring autophagy (4th Edition) DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin, H Abeliovich, ... Autophagy 17 (1), 1-382, 2021 | 14110* | 2021 |
| Nicastrin modulates presenilin-mediated notch/glp-1 signal transduction and βAPP processing G Yu, M Nishimura, S Arawaka, D Levitan, L Zhang, A Tandon, YQ Song, ... Nature 407 (6800), 48-54, 2000 | 1296 | 2000 |
| Early-onset amyloid deposition and cognitive deficits in transgenic mice expressing a double mutant form of amyloid precursor protein 695 MA Chishti, DS Yang, C Janus, AL Phinney, P Horne, J Pearson, ... Journal of Biological Chemistry 276 (24), 21562-21570, 2001 | 1228 | 2001 |
| Autophagy failure in Alzheimer's disease—locating the primary defect RA Nixon, DS Yang Neurobiology of disease 43 (1), 38-45, 2011 | 718 | 2011 |
| Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits DS Yang, P Stavrides, PS Mohan, S Kaushik, A Kumar, M Ohno, ... Brain 134 (1), 258-277, 2011 | 507 | 2011 |
| Neurodegenerative lysosomal disorders: a continuum from development to late age RA Nixon, DS Yang, JH Lee Autophagy 4 (5), 590-599, 2008 | 428 | 2008 |
| Faulty autolysosome acidification in Alzheimer’s disease mouse models induces autophagic build-up of Aβ in neurons, yielding senile plaques JH Lee, DS Yang, CN Goulbourne, E Im, P Stavrides, A Pensalfini, ... Nature neuroscience 25 (6), 688-701, 2022 | 422 | 2022 |
| Modulating factors in amyloid-β fibril formation J McLaurin, DS Yang, CM Yip, PE Fraser Journal of Structural Biology 130 (2-3), 259-270, 2000 | 345 | 2000 |
| Manipulating the amyloid-β aggregation pathway with chemical chaperones DS Yang, CM Yip, THJ Huang, A Chakrabartty, PE Fraser Journal of Biological Chemistry 274 (46), 32970-32974, 1999 | 333 | 1999 |
| Structural studies of soluble oligomers of the Alzheimer β-amyloid peptide TH Huang, DS Yang, NP Plaskos, S Go, CM Yip, PE Fraser, ... Journal of molecular biology 297 (1), 73-87, 2000 | 260 | 2000 |
| Autophagy and neuronal cell death in neurological disorders RA Nixon, DS Yang Cold Spring Harbor Perspectives in Biology 4 (10), 2012 | 219 | 2012 |
| Neuronal apoptosis and autophagy cross talk in aging PS/APP mice, a model of Alzheimer's disease DS Yang, A Kumar, P Stavrides, J Peterson, CM Peterhoff, M Pawlik, ... The American journal of pathology 173 (3), 665-681, 2008 | 218 | 2008 |
| Mature glycosylation and trafficking of nicastrin modulate its binding to presenilins DS Yang, A Tandon, F Chen, G Yu, H Yu, S Arawaka, H Hasegawa, ... Journal of Biological Chemistry 277 (31), 28135-28142, 2002 | 212 | 2002 |
| Copper (II)-induced conformational changes and protease resistance in recombinant and cellular PrP effect of protein age and deamidation K Qin, DS Yang, Y Yang, MA Chishti, LJ Meng, HA Kretzschmar, CM Yip, ... Journal of Biological Chemistry 275 (25), 19121-19131, 2000 | 199 | 2000 |
| Examining the zinc binding site of the amyloid‐β peptide DS Yang, JA McLaurin, K Qin, D Westaway, PE Fraser European Journal of Biochemistry 267 (22), 6692-6698, 2000 | 149 | 2000 |
| Presenilin structure, function and role in Alzheimer disease PE Fraser, DS Yang, G Yu, L Lévesque, M Nishimura, S Arawaka, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1502 (1), 1-15, 2000 | 149 | 2000 |
| Characterization of the Binding of Amyloid‐β Peptide to Cell Culture‐Derived Native Apolipoprotein E2, E3, and E4 Isoforms and to Isoforms from Human Plasma DS Yang, JD Smith, Z Zhou, SE Gandy, RN Martins Journal of neurochemistry 68 (2), 721-725, 1997 | 147 | 1997 |
| Apolipoprotein E promotes the binding and uptake of β-amyloid into Chinese hamster ovary cells in an isoform-specific manner DS Yang, DH Small, U Seydel, JD Smith, J Hallmayer, SE Gandy, ... Neuroscience 90 (4), 1217-1226, 1999 | 144 | 1999 |
| Marked calpastatin (CAST) depletion in Alzheimer's disease accelerates cytoskeleton disruption and neurodegeneration: neuroprotection by CAST overexpression MV Rao, PS Mohan, CM Peterhoff, DS Yang, SD Schmidt, PH Stavrides, ... Journal of Neuroscience 28 (47), 12241-12254, 2008 | 141 | 2008 |
| Single-walled carbon nanotubes alleviate autophagic/lysosomal defects in primary glia from a mouse model of Alzheimer’s disease X Xue, LR Wang, Y Sato, Y Jiang, M Berg, DS Yang, RA Nixon, XJ Liang Nano letters 14 (9), 5110-5117, 2014 | 127 | 2014 |
Ralph A NixonProfessor of Psychiatry and Cell Biology New York UniversityVerified email at nki.rfmh.org
