Advances in local therapy for glioblastoma—taking the fight to the tumour TS van Solinge, L Nieland, EA Chiocca, MLD Broekman Nature Reviews Neurology 18 (4), 221-236, 2022 | 221 | 2022 |
Glioblastoma-associated microglia reprogramming is mediated by functional transfer of extracellular miR-21 ER Abels, SLN Maas, L Nieland, Z Wei, PS Cheah, E Tai, CJ Kolsteeg, ... Cell reports 28 (12), 3105-3119. e7, 2019 | 202 | 2019 |
Extracellular vesicle-mediated bilateral communication between glioblastoma and astrocytes L Nieland, LM Morsett, MLD Broekman, XO Breakefield, ER Abels Trends in neurosciences 44 (3), 215-226, 2021 | 62 | 2021 |
Engineered EVs designed to target diseases of the CNS L Nieland, S Mahjoum, E Grandell, K Breyne, XO Breakefield Journal of Controlled Release 356, 493-506, 2023 | 33 | 2023 |
Comparative analysis identifies similarities between the human and murine microglial sensomes ER Abels, L Nieland, S Hickman, MLD Broekman, J El Khoury, SLN Maas International journal of molecular sciences 22 (3), 1495, 2021 | 31 | 2021 |
CRISPR-Cas knockout of miR21 reduces glioma growth L Nieland, TS van Solinge, PS Cheah, LM Morsett, J El Khoury, ... Molecular Therapy-Oncolytics 25, 121-136, 2022 | 30 | 2022 |
Roles of extracellular vesicles in glioblastoma: foes, friends and informers TR Lunavat, L Nieland, AB Vrijmoet, A Zargani-Piccardi, Y Samaha, ... Frontiers in Oncology 13, 1291177, 2023 | 7 | 2023 |
Virotherapy: The next addition to the standard of care for glioblastoma? MLD Broekman, L Nieland, RC Hoeben Cancer Cell 40 (10), 1089-1091, 2022 | 4 | 2022 |
Tracking human neurologic disease status in mouse brain/plasma using reporter-tagged, EV-associated biomarkers KE Maalouf, CA Vaine, DM Frederick, A Yoshinaga, W Obuchi, ... Molecular Therapy 31 (7), 2206-2219, 2023 | 1 | 2023 |
CRISPR targeting of mmu-miR-21a through a single adeno-associated virus vector prolongs survival of glioblastoma-bearing mice L Nieland, AB Vrijmoet, IW Jetten, D Rufino-Ramos, AJEM de Reus, ... Molecular Therapy 33 (1), 133-151, 2025 | | 2025 |
Expression-based selection identifies a microglia-tropic AAV capsid for direct and CSF routes of administration in mice MC Santoscoy, P Espinoza, KS Hanlon, L Yang, L Nieland, C Ng, ... bioRxiv, 2024 | | 2024 |
EXTH-55. ALL-IN-ONE GENETIC CONSTRUCT TO KNOCKDOWN MIR-21 REDUCES GLIOMA PROLIFERATION IN VITRO L Nieland, A Vrijmoet, A de Reus, B Kleinsteiver, M Broekman, ... Neuro-Oncology 25 (Suppl 5), v236, 2023 | | 2023 |
Astrogreen Transgenic Mouse Illuminates the Trafficking of Astrocyte-Derived Extracellular Vesicles L Nieland, E Abou Haidar, D Rufino-Ramos, Y Samaha, K Breyne, ... Available at SSRN 4994730, 0 | | |
bels, ER (2021) L Nieland, LM Morsett, MLD Broekman, XO Breakefield Extracellular esicle-mediated bilateral communication between glioblastoma …, 0 | | |