Targeting biosynthetic networks of the proinflammatory and proresolving lipid metabolome M Werner, PM Jordan, E Romp, A Czapka, Z Rao, C Kretzer, A Koeberle, ... The FASEB Journal 33 (5), 6140, 2019 | 118 | 2019 |
SARS-CoV-2 causes severe epithelial inflammation and barrier dysfunction S Deinhardt-Emmer, S Böttcher, C Häring, L Giebeler, A Henke, R Zell, ... Journal of virology 95 (10), 10.1128/jvi. 00110-21, 2021 | 93 | 2021 |
Staphylococcus aureus-derived α-hemolysin evokes generation of specialized pro-resolving mediators promoting inflammation resolution PM Jordan, J Gerstmeier, S Pace, R Bilancia, Z Rao, F Börner, L Miek, ... Cell reports 33 (2), 2020 | 65 | 2020 |
Specialized pro‐resolving mediators: biosynthesis and biological role in bacterial infections PM Jordan, O Werz The FEBS journal 289 (14), 4212-4227, 2022 | 36 | 2022 |
Vacuolar (H+)-ATPase critically regulates specialized proresolving mediator pathways in human M2-like monocyte-derived macrophages and has a crucial role in resolution of … Z Rao, S Pace, PM Jordan, R Bilancia, F Troisi, F Börner, N Andreas, ... The Journal of Immunology 203 (4), 1031-1043, 2019 | 32 | 2019 |
ATP/IL‐33‐triggered hyperactivation of mast cells results in an amplified production of pro‐inflammatory cytokines and eicosanoids PM Jordan, N Andreas, M Groth, P Wegner, F Weber, U Jäger, C Küchler, ... Immunology 164 (3), 541-554, 2021 | 27 | 2021 |
Anti-inflammatory celastrol promotes a switch from leukotriene biosynthesis to formation of specialized pro-resolving lipid mediators S Pace, K Zhang, PM Jordan, R Bilancia, W Wang, F Börner, ... Pharmacological research 167, 105556, 2021 | 27 | 2021 |
Encapsulation of the dual FLAP/mPEGS-1 inhibitor BRP-187 into acetalated dextran and PLGA nanoparticles improves its cellular bioactivity B Shkodra-Pula, C Kretzer, PM Jordan, P Klemm, A Koeberle, D Pretzel, ... Journal of Nanobiotechnology 18, 1-14, 2020 | 27 | 2020 |
Shifting the biosynthesis of leukotrienes toward specialized pro-resolving mediators by the 5-lipoxygenase-activating protein (FLAP) antagonist BRP-201 C Kretzer, PM Jordan, R Bilancia, A Rossi, T Gür Maz, E Banoglu, ... Journal of inflammation research, 911-925, 2022 | 25 | 2022 |
Allosteric activation of 15‐lipoxygenase‐1 by boswellic acid induces the lipid mediator class switch to promote resolution of inflammation F Börner, S Pace, PM Jordan, J Gerstmeier, M Gomez, A Rossi, ... Advanced Science 10 (6), 2205604, 2023 | 22 | 2023 |
Natural chalcones elicit formation of specialized pro-resolving mediators and related 15-lipoxygenase products in human macrophages C Kretzer, PM Jordan, KPL Meyer, D Hoff, M Werner, RK Hofstetter, ... Biochemical Pharmacology 195, 114825, 2022 | 22 | 2022 |
Establishment and characterization of mild atopic dermatitis in the DNCB-induced mouse model R Riedl, A Kühn, D Rietz, B Hebecker, KG Glowalla, LK Peltner, ... International journal of molecular sciences 24 (15), 12325, 2023 | 19 | 2023 |
Ethoxy acetalated dextran nanoparticles for drug delivery: A comparative study of formulation methods M Behnke, P Klemm, P Dahlke, B Shkodra, B Beringer-Siemers, ... International Journal of Pharmaceutics: X 5, 100173, 2023 | 16 | 2023 |
Cannabidiol acts as molecular switch in innate immune cells to promote the biosynthesis of inflammation-resolving lipid mediators LK Peltner, L Gluthmann, F Börner, S Pace, RK Hoffstetter, C Kretzer, ... Cell Chemical Biology 30 (12), 1508-1524. e7, 2023 | 15 | 2023 |
Novel potent benzimidazole-based microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors derived from BRP-201 that also inhibit leukotriene C4 synthase AG Ergül, TG Maz, C Kretzer, A Olğaç, PM Jordan, B Çalışkan, O Werz, ... European Journal of Medicinal Chemistry 231, 114167, 2022 | 15 | 2022 |
The natural combination medicine traumeel (Tr14) improves resolution of inflammation by promoting the biosynthesis of specialized pro-resolving mediators PM Jordan, E van Goethem, AM Müller, K Hemmer, V Gavioli, V Baillif, ... Pharmaceuticals 14 (11), 1123, 2021 | 15 | 2021 |
Beneficial Modulation of Lipid Mediator Biosynthesis in Innate Immune Cells by Antirheumatic Tripterygium wilfordii Glycosides K Zhang, S Pace, PM Jordan, LK Peltner, A Weber, D Fischer, ... Biomolecules 11 (5), 746, 2021 | 15 | 2021 |
Lipid droplets control mitogenic lipid mediator production in human cancer cells EJ Jovičić, AP Janež, TO Eichmann, Š Koren, V Brglez, PM Jordan, ... Molecular metabolism 76, 101791, 2023 | 14 | 2023 |
Proteomic and lipidomic profiling of demyelinating lesions identifies fatty acids as modulators in lesion recovery H Penkert, A Bertrand, V Tiwari, S Breimann, SA Müller, PM Jordan, ... Cell Reports 37 (4), 2021 | 14 | 2021 |
Osteocytes Serve as a Reservoir for Intracellular Persisting Staphylococcus aureus Due to the Lack of Defense Mechanisms M Garcia-Moreno, PM Jordan, K Günther, T Dau, C Fritzsch, M Vermes, ... Frontiers in Microbiology 13, 937466, 2022 | 13 | 2022 |