NAD+ cleavage activity by animal and plant TIR domains in cell death pathways S Horsefield, H Burdett, X Zhang, MK Manik, Y Shi, J Chen, T Qi, J Gilley, ... Science 365 (6455), 793-799, 2019 | 463 | 2019 |
SARM1 is a metabolic sensor activated by an increased NMN/NAD+ ratio to trigger axon degeneration MD Figley, W Gu, JD Nanson, Y Shi, Y Sasaki, K Cunnea, AK Malde, X Jia, ... Neuron 109 (7), 1118-1136. e11, 2021 | 239 | 2021 |
Structural basis of sterol recognition and nonvesicular transport by lipid transfer proteins anchored at membrane contact sites J Tong, MK Manik, YJ Im Proceedings of the National Academy of Sciences 115 (5), E856-E865, 2018 | 95 | 2018 |
Cyclic ADP ribose isomers: Production, chemical structures, and immune signaling MK Manik, Y Shi, S Li, MA Zaydman, N Damaraju, S Eastman, TG Smith, ... Science 377 (6614), eadc8969, 2022 | 91 | 2022 |
Structural basis of NLR activation and innate immune signalling in plants N Maruta, H Burdett, BYJ Lim, X Hu, S Desa, MK Manik, B Kobe Immunogenetics 74 (1), 5-26, 2022 | 82 | 2022 |
A comparative study of the antioxidant, antimicrobial, cytotoxic and thrombolytic potential of the fruits and leaves of Spondias dulcis SMA Islam, KT Ahmed, MK Manik, MA Wahid, CSI Kamal Asian Pacific journal of tropical biomedicine 3 (9), 682-691, 2013 | 74 | 2013 |
Structure of yeast OSBP-related protein Osh1 reveals key determinants for lipid transport and protein targeting at the nucleus-vacuole junction MK Manik, H Yang, J Tong, YJ Im Structure 25 (4), 617-629. e3, 2017 | 68 | 2017 |
Structural insights into nonvesicular lipid transport by the oxysterol binding protein homologue family J Tong, MK Manik, H Yang, YJ Im Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2016 | 50 | 2016 |
Plant and prokaryotic TIR domains generate distinct cyclic ADPR NADase products AM Bayless, S Chen, SC Ogden, X Xu, JD Sidda, MK Manik, S Li, B Kobe, ... Science Advances 9 (11), eade8487, 2023 | 45 | 2023 |
A comparative study of the antioxidant, antimicrobial and thrombolytic activity of the bark and leaves of Lannea coromandelica (Anacardiaceae) MK Manik, MA Wahid, SMA Islam, A Pal, KT Ahmed International Journal of Pharmaceutical Sciences and Research 4 (7), 2609, 2013 | 45 | 2013 |
Structural evolution of TIR-domain signalosomes S Nimma, W Gu, N Maruta, Y Li, M Pan, FK Saikot, BYJ Lim, ... Frontiers in Immunology 12, 784484, 2021 | 41 | 2021 |
Investigation of in vitro antioxidant, antimicrobial and thrombolytic activity of the exocarp of Spondias pinnata (Anacardiaceae) MK Manik, SMA Islam, MA Wahid, MM Morshed, S Kamal, MS Islam, ... Canadian Chemical Transactions 1 (3), 191-201, 2013 | 28 | 2013 |
Toll/interleukin-1 receptor domains in bacterial and plant immunity S Li, MK Manik, Y Shi, B Kobe, T Ve Current Opinion in Microbiology 74, 102316, 2023 | 12 | 2023 |
Chemical structures of cyclic ADP ribose (cADPR) isomers and the molecular basis of their production and signaling MK Manik, Y Shi, S Li, MA Zaydman, N Damaraju, S Eastman, TG Smith, ... BioRxiv, 2022.05. 07.491051, 2022 | 9 | 2022 |
Crystal structure of the Toll/interleukin‐1 receptor (TIR) domain of IL‐1R10 provides structural insights into TIR domain signalling S Nimma, W Gu, MK Manik, T Ve, JD Nanson, B Kobe FEBS letters 596 (7), 886-897, 2022 | 9 | 2022 |
AICAR transformylase/IMP cyclohydrolase (ATIC) is essential for de novo purine biosynthesis and infection by Cryptococcus neoformans MSI Wizrah, SMH Chua, Z Luo, MK Manik, M Pan, JML Whyte, ... Journal of Biological Chemistry 298 (10), 2022 | 6 | 2022 |
Homology Modeling and Microarray Analysis of Silicon Transporter Protein in Rice, Barley and Maize MAA Mohammad K. Manik and Mohammad N. Morshed Mohammed M. Morshed Canadian Chemical Transactions 1 (4), 326-337, 2013 | 1 | 2013 |
Structural basis for TIR domain–mediated innate immune signaling by Toll-like receptor adaptors TRIF and TRAM MK Manik, M Pan, L Xiao, W Gu, H Kim, S Pospich, A Hedger, ... Proceedings of the National Academy of Sciences 122 (2), e2418988122, 2025 | | 2025 |
Structural evolution of TIR-domain signalosomes in mammalian, plant and bacterial immunity characterized by integrative structural biology B Kobe, JD Nanson, MK Manik, S Li, W Gu, M Pan, Y Li, TW Muusse, ... Acta Crystallographica Section A Foundations and Advances 79 (a2), C246-C246, 2023 | | 2023 |
Activated bacterial TIR proteins: NADase activity and filamentous assemblies S Li, MK Manik, T Ve, JD Nanson, B Kobe Acta Crystallographica Section A Foundations and Advances 79 (a2), C931-C931, 2023 | | 2023 |