Therapeutic potential of flavonoids in pain and inflammation: mechanisms of action, pre-clinical and clinical data, and pharmaceutical development CR Ferraz, TT Carvalho, MF Manchope, NA Artero, FS Rasquel-Oliveira, ... Molecules 25 (3), 762, 2020 | 279 | 2020 |
Vanillic acid inhibits inflammatory pain by inhibiting neutrophil recruitment, oxidative stress, cytokine production, and NFκB activation in mice C Calixto-Campos, TT Carvalho, MSN Hohmann, FA Pinho-Ribeiro, ... Journal of natural products 78 (8), 1799-1808, 2015 | 221 | 2015 |
Naringenin reduces inflammatory pain in mice FA Pinho-Ribeiro, AC Zarpelon, V Fattori, MF Manchope, SS Mizokami, ... Neuropharmacology 105, 508-519, 2016 | 189 | 2016 |
Protective effects of the flavonoid hesperidin methyl chalcone in inflammation and pain in mice: role of TRPV1, oxidative stress, cytokines and NF-κB FA Pinho-Ribeiro, MSN Hohmann, SM Borghi, AC Zarpelon, CFS Guazelli, ... Chemico-biological interactions 228, 88-99, 2015 | 143 | 2015 |
Naringenin Inhibits Superoxide Anion-Induced Inflammatory Pain: Role of Oxidative Stress, Cytokines, Nrf-2 and the NO−cGMP−PKG−KATPChannel Signaling … MF Manchope, C Calixto-Campos, L Coelho-Silva, AC Zarpelon, ... PloS one 11 (4), e0153015, 2016 | 134 | 2016 |
Contribution of Nrf2 modulation to the mechanism of action of analgesic and anti-inflammatory drugs in pre-clinical and clinical stages L Staurengo-Ferrari, S Badaro-Garcia, MSN Hohmann, MF Manchope, ... Frontiers in pharmacology 9, 1536, 2019 | 116 | 2019 |
Naringenin: an analgesic and anti-inflammatory citrus flavanone MF Manchope, R Casagrande, WA Verri Jr Oncotarget 8 (3), 3766, 2016 | 101 | 2016 |
The superoxide anion donor, potassium superoxide, induces pain and inflammation in mice through production of reactive oxygen species and cyclooxygenase-2 NA Maioli, AC Zarpelon, SS Mizokami, C Calixto-Campos, CFS Guazelli, ... Brazilian Journal of Medical and Biological Research 48, 321-331, 2015 | 53 | 2015 |
Targeting IL-33/ST2 signaling: regulation of immune function and analgesia V Fattori, MSN Hohmann, AC Rossaneis, MF Manchope, JC Alves-Filho, ... Expert opinion on therapeutic targets 21 (12), 1141-1152, 2017 | 49 | 2017 |
Probucol attenuates lipopolysaccharide-induced leukocyte recruitment and inflammatory hyperalgesia: effect on NF-кB activation and cytokine production AZ Zucoloto, MF Manchope, L Staurengo-Ferrari, FA Pinho-Ribeiro, ... European journal of pharmacology 809, 52-63, 2017 | 36 | 2017 |
RvD1 disrupts nociceptor neuron and macrophage activation and neuroimmune communication, reducing pain and inflammation in gouty arthritis in mice TH Zaninelli, V Fattori, T Saraiva‐Santos, S Badaro‐Garcia, ... British journal of pharmacology 179 (18), 4500-4515, 2022 | 31 | 2022 |
Jararhagin-induced mechanical hyperalgesia depends on TNF-α, IL-1β and NFκB in mice CR Ferraz, C Calixto-Campos, MF Manchope, R Casagrande, PB Clissa, ... Toxicon 103, 119-128, 2015 | 31 | 2015 |
Naringenin mitigates titanium dioxide (TiO2)-induced chronic arthritis in mice: role of oxidative stress, cytokines, and NFκB MF Manchope, NA Artero, V Fattori, SS Mizokami, DL Pitol, JPM Issa, ... Inflammation Research 67, 997-1012, 2018 | 30 | 2018 |
Hesperidin methyl chalcone interacts with NFκB Ser276 and inhibits zymosan-induced joint pain and inflammation, and RAW 264.7 macrophage activation FS Rasquel-Oliveira, MF Manchope, L Staurengo-Ferrari, CR Ferraz, ... Inflammopharmacology 28, 979-992, 2020 | 29 | 2020 |
Methyl gallate attenuates inflammation induced by Toll-like receptor ligands by inhibiting MAPK and NF-Κb signaling pathways LB Correa, LN Seito, MF Manchope, WA Verri, TM Cunha, MG Henriques, ... Inflammation Research 69, 1257-1270, 2020 | 27 | 2020 |
The granulopoietic cytokine granulocyte colony-stimulating factor (G-CSF) induces pain: Analgesia by rutin TT Carvalho, SS Mizokami, CR Ferraz, MF Manchope, SM Borghi, ... Inflammopharmacology 27, 1285-1296, 2019 | 22 | 2019 |
Probucol ameliorates complete freund’s adjuvant-induced hyperalgesia by targeting peripheral and spinal cord inflammation AZ Zucoloto, MF Manchope, SM Borghi, TS Dos Santos, V Fattori, ... Inflammation 42, 1474-1490, 2019 | 21 | 2019 |
Efeito anti-inflamatório do gengibre e possível via de sinalização NA Vieira, FN Tomiotto, GP Melo, MF Manchope, NR de Lima, ... Semina: ciências biológicas e da saúde 35 (1), 149-162, 2014 | 21 | 2014 |
Quercetin as an antiinflammatory analgesic CR Ferraz, A Franciosi, NB Emidio, FS Rasquel-Oliveira, MF Manchope, ... A centum of valuable plant bioactives, 319-347, 2021 | 14 | 2021 |
Chikungunya virus and its envelope protein E2 induce hyperalgesia in mice: Inhibition by anti-E2 monoclonal antibodies and by targeting TRPV1 CZ Segato-Vendrameto, C Zanluca, AZ Zucoloto, TH Zaninelli, ... Cells 12 (4), 556, 2023 | 12 | 2023 |