Understanding multicellular function and disease with human tissue-specific networks CS Greene, A Krishnan, AK Wong, E Ricciotti, RA Zelaya, ... Nature genetics 47 (6), 569-576, 2015 | 925 | 2015 |
Deep learning sequence-based ab initio prediction of variant effects on expression and disease risk J Zhou, CL Theesfeld, K Yao, KM Chen, AK Wong, OG Troyanskaya Nature genetics 50 (8), 1171-1179, 2018 | 585 | 2018 |
Genome-wide prediction and functional characterization of the genetic basis of autism spectrum disorder A Krishnan, R Zhang, V Yao, CL Theesfeld, AK Wong, A Tadych, ... Nature neuroscience 19 (11), 1454-1462, 2016 | 458 | 2016 |
Coat variation in the domestic dog is governed by variants in three genes E Cadieu, MW Neff, P Quignon, K Walsh, K Chase, HG Parker, ... Science 326 (5949), 150, 2009 | 414 | 2009 |
Tracking footprints of artificial selection in the dog genome JM Akey, AL Ruhe, DT Akey, AK Wong, CF Connelly, J Madeoy, ... Proceedings of the National Academy of Sciences 107 (3), 1160-1165, 2010 | 383 | 2010 |
Whole-genome deep-learning analysis identifies contribution of noncoding mutations to autism risk J Zhou, CY Park, CL Theesfeld, AK Wong, Y Yuan, C Scheckel, JJ Fak, ... Nature genetics 51 (6), 973-980, 2019 | 306 | 2019 |
Breed distribution and history of canine mdr1-1Δ, a pharmacogenetic mutation that marks the emergence of breeds from the collie lineage MW Neff, KR Robertson, AK Wong, N Safra, KW Broman, M Slatkin, ... Proceedings of the National Academy of Sciences of the United States of …, 2004 | 273 | 2004 |
A sequence-based global map of regulatory activity for deciphering human genetics KM Chen, AK Wong, OG Troyanskaya, J Zhou Nature genetics 54 (7), 940-949, 2022 | 161 | 2022 |
Targeted exploration and analysis of large cross-platform human transcriptomic compendia Q Zhu, AK Wong, A Krishnan, MR Aure, A Tadych, R Zhang, DC Corney, ... Nature methods 12 (3), 211-214, 2015 | 153 | 2015 |
Tissue-specific functional networks for prioritizing phenotype and disease genes Y Guan, D Gorenshteyn, M Burmeister, AK Wong, JC Schimenti, ... Public Library of Science 8 (9), e1002694, 2012 | 146 | 2012 |
Necrotizing meningoencephalitis of Pug dogs associates with dog leukocyte antigen class II and resembles acute variant forms of multiple sclerosis KA Greer, AK Wong, H Liu, TR Famula, NC Pedersen, A Ruhe, M Wallace, ... Tissue Antigens 76 (2), 110-118, 2010 | 131 | 2010 |
A comprehensive linkage map of the dog genome AK Wong, AL Ruhe, BL Dumont, KR Robertson, G Guerrero, SM Shull, ... Genetics 184 (2), 595, 2010 | 127 | 2010 |
IMP: a multi-species functional genomics portal for integration, visualization and prediction of protein functions and networks AK Wong, CY Park, CS Greene, LA Bongo, Y Guan, OG Troyanskaya Nucleic acids research 40 (W1), W484-W490, 2012 | 110 | 2012 |
SARS-CoV-2 receptor networks in diabetic and COVID-19–associated kidney disease R Menon, EA Otto, R Sealfon, V Nair, AK Wong, CL Theesfeld, X Chen, ... Kidney international 98 (6), 1502-1518, 2020 | 83 | 2020 |
GIANT 2.0: genome-scale integrated analysis of gene networks in tissues AK Wong, A Krishnan, OG Troyanskaya Nucleic acids research 46 (W1), W65-W70, 2018 | 79 | 2018 |
Decoding disease: from genomes to networks to phenotypes AK Wong, RSG Sealfon, CL Theesfeld, OG Troyanskaya Nature Reviews Genetics 22 (12), 774-790, 2021 | 78 | 2021 |
IMP 2.0: a multi-species functional genomics portal for integration, visualization and prediction of protein functions and networks AK Wong, A Krishnan, V Yao, A Tadych, OG Troyanskaya Nucleic acids research 43 (W1), W128-W133, 2015 | 75 | 2015 |
Functional knowledge transfer for high-accuracy prediction of under-studied biological processes CY Park, AK Wong, CS Greene, J Rowland, Y Guan, LA Bongo, ... PLoS computational biology 9 (3), e1002957, 2013 | 74 | 2013 |
Genome-wide landscape of RNA-binding protein target site dysregulation reveals a major impact on psychiatric disorder risk CY Park, J Zhou, AK Wong, KM Chen, CL Theesfeld, RB Darnell, ... Nature genetics 53 (2), 166-173, 2021 | 69 | 2021 |
An integrative tissue-network approach to identify and test human disease genes V Yao, R Kaletsky, W Keyes, DE Mor, AK Wong, S Sohrabi, CT Murphy, ... Nature biotechnology 36 (11), 1091-1099, 2018 | 68 | 2018 |