CD38 dictates age-related NAD decline and mitochondrial dysfunction through an SIRT3-dependent mechanism J Camacho-Pereira, MG Tarragó, CCS Chini, V Nin, C Escande, ... Cell metabolism 23 (6), 1127-1139, 2016 | 846 | 2016 |
Targeting senescent cells alleviates obesity‐induced metabolic dysfunction AK Palmer, M Xu, YI Zhu, T Pirtskhalava, MM Weivoda, CM Hachfeld, ... Aging cell 18 (3), e12950, 2019 | 541 | 2019 |
Mitochondrial dysfunction in cell senescence and aging S Miwa, S Kashyap, E Chini, T von Zglinicki The Journal of clinical investigation 132 (13), 2022 | 461 | 2022 |
Cellular senescence in type 2 diabetes: a therapeutic opportunity AK Palmer, T Tchkonia, NK LeBrasseur, EN Chini, M Xu, JL Kirkland Diabetes 64 (7), 2289-2298, 2015 | 458 | 2015 |
Regulation of intracellular levels of NAD: a novel role for CD38 P Aksoy, TA White, M Thompson, EN Chini Biochemical and biophysical research communications 345 (4), 1386-1392, 2006 | 420 | 2006 |
Flavonoid Apigenin Is an Inhibitor of the NAD+ase CD38: Implications for Cellular NAD+ Metabolism, Protein Acetylation, and Treatment of Metabolic Syndrome C Escande, V Nin, NL Price, V Capellini, AP Gomes, MT Barbosa, ... Diabetes 62 (4), 1084-1093, 2013 | 384 | 2013 |
A potent and specific CD38 inhibitor ameliorates age-related metabolic dysfunction by reversing tissue NAD+ decline MG Tarragó, CCS Chini, KS Kanamori, GM Warner, A Caride, ... Cell metabolism 27 (5), 1081-1095. e10, 2018 | 326 | 2018 |
The multi-faceted ecto-enzyme CD38: roles in immunomodulation, cancer, aging, and metabolic diseases KA Hogan, CCS Chini, EN Chini Frontiers in immunology 10, 1187, 2019 | 315 | 2019 |
The enzyme CD38 (a NAD glycohydrolase, EC 3.2. 2.5) is necessary for the development of diet‐induced obesity MTP Barbosa, SM Soares, CM Novak, D Sinclair, JA Levine, P Aksoy, ... The FASEB Journal 21 (13), 3629-3639, 2007 | 304 | 2007 |
Abscisic acid controls calcium-dependent egress and development in Toxoplasma gondii K Nagamune, LM Hicks, B Fux, F Brossier, EN Chini, LD Sibley Nature 451 (7175), 207-210, 2008 | 266 | 2008 |
CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD+ and NMN levels CCS Chini, TR Peclat, GM Warner, S Kashyap, JM Espindola-Netto, ... Nature metabolism 2 (11), 1284-1304, 2020 | 258 | 2020 |
CD38 as a regulator of cellular NAD: a novel potential pharmacological target for metabolic conditions EN Chini Current pharmaceutical design 15 (1), 57-63, 2009 | 230 | 2009 |
NAD and the aging process: Role in life, death and everything in between CCS Chini, MG Tarragó, EN Chini Molecular and cellular endocrinology 455, 62-74, 2017 | 227 | 2017 |
Regulation of SIRT 1 mediated NAD dependent deacetylation: a novel role for the multifunctional enzyme CD38 P Aksoy, C Escande, TA White, M Thompson, S Soares, JC Benech, ... Biochemical and biophysical research communications 349 (1), 353-359, 2006 | 220 | 2006 |
Deleted in breast cancer–1 regulates SIRT1 activity and contributes to high-fat diet–induced liver steatosis in mice C Escande, CCS Chini, V Nin, KM Dykhouse, CM Novak, J Levine, ... The Journal of clinical investigation 120 (2), 545-558, 2010 | 218 | 2010 |
Adrenomedullin suppresses mitogenesis in rat mesangial cells via cAMP pathway EN Chini, E Choi, JP Grande, JC Burnett, TP Dousa Biochemical and biophysical research communications 215 (3), 868-873, 1995 | 211 | 1995 |
The pharmacology of CD38/NADase: an emerging target in cancer and diseases of aging EN Chini, CCS Chini, JME Netto, GC de Oliveira, W van Schooten Trends in pharmacological sciences 39 (4), 424-436, 2018 | 204 | 2018 |
Nicotinate Adenine Dinucleotide Phosphate (NAADP) Triggers a Specific Calcium Release System in Sea Urchin Eggs (∗) EN Chini, KW Beers, TP Dousa Journal of Biological Chemistry 270 (7), 3216-3223, 1995 | 203 | 1995 |
Cytoprotective effects of adrenomedullin in glomerular cell injury: central role of cAMP signaling pathway EN Chini, CCS Chini, C Bolliger, M Jougasaki, JP Grande, JC Burnett Jr, ... Kidney international 52 (4), 917-925, 1997 | 201 | 1997 |
Complications after unintentional intra-arterial injection of drugs: risks, outcomes, and management strategies S Sen, EN Chini, MJ Brown Mayo Clinic Proceedings 80 (6), 783-795, 2005 | 177 | 2005 |