| Antidepressant drugs act by directly binding to TRKB neurotrophin receptors PC Casarotto, M Girych, SM Fred, V Kovaleva, R Moliner, G Enkavi, ... Cell 184 (5), 1299-1313. e19, 2021 | 535 | 2021 |
| Psychedelics promote plasticity by directly binding to BDNF receptor TrkB R Moliner, M Girych, CA Brunello, V Kovaleva, C Biojone, G Enkavi, ... Nature Neuroscience 26 (6), 1032-1041, 2023 | 254 | 2023 |
| Antidepressant and Antipsychotic Drugs Reduce Viral Infection by SARS-CoV-2 and Fluoxetine Shows Antiviral Activity Against the Novel Variants in vitro SM Fred, S Kuivanen, H Ugurlu, PC Casarotto, L Levanov, K Saksela, ... Frontiers in Pharmacology 12, 755600, 2022 | 59 | 2022 |
| Pharmacologically diverse antidepressants facilitate TRKB receptor activation by disrupting its interaction with the endocytic adaptor complex AP-2 SM Fred, L Laukkanen, CA Brunello, L Vesa, H Göös, I Cardon, R Moliner, ... Journal of Biological Chemistry 294 (48), 18150-18161, 2019 | 47 | 2019 |
| Chondroitinase and antidepressants promote plasticity by releasing TRKB from dephosphorylating control of PTPσ in parvalbumin neurons A Lesnikova, PC Casarotto, SM Fred, M Voipio, F Winkel, A Steinzeig, ... Journal of Neuroscience 41 (5), 972-980, 2021 | 46 | 2021 |
| Antidepressant-like effect of losartan involves TRKB transactivation from angiotensin receptor type 2 (AGTR2) and recruitment of FYN CRAF Diniz, PC Casarotto, SM Fred, C Biojone, E Castrén, SRL Joca Neuropharmacology 135, 163-171, 2018 | 46 | 2018 |
| Longitudinal two-photon imaging in somatosensory cortex of behaving mice reveals dendritic spine formation enhancement by subchronic administration of low-dose ketamine E Pryazhnikov, E Mugantseva, P Casarotto, J Kolikova, SM Fred, ... Scientific reports 8 (1), 6464, 2018 | 46 | 2018 |
| Cholesterol‐recognition motifs in the transmembrane domain of the tyrosine kinase receptor family: The case of TRKB C Cannarozzo, SM Fred, M Girych, C Biojone, G Enkavi, T Róg, ... European Journal of Neuroscience 53 (10), 3311-3322, 2021 | 28 | 2021 |
| Perineuronal net receptor PTPσ regulates retention of memories A Lesnikova, P Casarotto, R Moliner, SM Fred, C Biojone, E Castrén Frontiers in Synaptic Neuroscience 13, 672475, 2021 | 14 | 2021 |
| nNOS-induced tyrosine nitration of TRKB impairs BDNF signaling and restrains neuronal plasticity C Biojone, PC Casarotto, C Cannarozzo, SM Fred, R Herrera-Rodríguez, ... Progress in Neurobiology 222, 102413, 2023 | 13 | 2023 |
| TRKB interaction with PSD95 is associated with latency of fluoxetine and 2R, 6R‐hydroxynorketamine SM Fred, R Moliner, H Antila, KA Engelhardt, OM Schlüter, PC Casarotto, ... European Journal of Neuroscience 57 (8), 1215-1224, 2023 | 4 | 2023 |
| Antidepressant and antipsychotic drugs reduce viral infection by SARS-CoV-2 and fluoxetine shows antiviral activity against the novel variants in vitro. Front Pharmacol. 2022 … SM Fred, S Kuivanen, H Ugurlu, PC Casarotto, L Levanov, K Saksela Publisher Full Text, 2021 | 4 | 2021 |
| Pharmacologically diverse antidepressant drugs disrupt the interaction of BDNF receptor TRKB and the endocytic adaptor AP-2 SM Fred, L Laukkanen, L Vesa, H Goos, I Cardon, R Moliner, T Maritzen, ... BioRxiv, 591909, 2019 | 2 | 2019 |
| Nitric oxide-induced tyrosine nitration of TrkB impairs BDNF signaling and restrains neuronal plasticity C Biojone, PC Casarotto, C Cannarozzo, SM Fred, R Herrera-Rodríguez, ... bioRxiv, 2022.05. 07.491033, 2022 | 1 | 2022 |
| Antidepressants act by binding to the transmembrane domain of TRKB receptor PC Casarotto, M Girych, SM Fred, R Moliner, G Enkavi, C Biojone, ... bioRxiv, 757989, 2019 | 1 | 2019 |
| The Role of TRKB Receptor Complex Proteins and the Lipid Environment In the Mechanism of Antidepressant Drug Action SM Fred Helsingin yliopisto, 2022 | | 2022 |
| Facilitation of fear extinction by nNOS inhibitor depends on BDNF/TRKB signaling: potential involvement of TRKB nitration C Biojone, P Casarotto, C Cannarozzo, SM Fred, R Herrera-Rodríguez, ... Neuroscience Applied 1, 100364, 2022 | | 2022 |
| Cholesterol-dependent effect of antidepressants on activation BDNF receptor (TRKB) P Casarotto, SM Fred, C Biojone, M Girych, T Rog, I Vattulainen, ... European Neuropsychopharmacology 29, S319-S320, 2019 | | 2019 |
| Pharmacologically diverse antidepressant drugs disrupt the interaction of neurotrophic factor receptor TRKB and endocytic adaptor protein complex AP-2 SM Fred, L Laukkanen, L Vesa, A Lesnikova, H Göös, M Varjosalo, ... European Neuropsychopharmacology 29, S283-S284, 2019 | | 2019 |
| P. 1.06 TRKB receptor interaction with postsynaptic density proteins (PSD93 and PSD95) in the mechanism of antidepressants SM Fred, P Casarotto, R Moliner, H Antila, O Schlüter, E Castrén | | 2019 |
