A synonymous polymorphism in a common MDR1 (ABCB1) haplotype shapes protein function KL Fung, MM Gottesman Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1794 (5), 860-871, 2009 | 455 | 2009 |
Inhibition of urease by bismuth (III): Implications for the mechanism of action of bismuth drugs L Zhang, SB Mulrooney, AFK Leung, Y Zeng, BBC Ko, RP Hausinger, ... Biometals 19 (5), 503-511, 2006 | 170 | 2006 |
MDR1 Synonymous Polymorphisms Alter Transporter Specificity and Protein Stability in a Stable Epithelial Monolayer KL Fung, J Pan, S Ohnuma, PE Lund, JN Pixley, C Kimchi-Sarfaty, ... Cancer research 74 (2), 598-608, 2014 | 130 | 2014 |
Tariquidar is an Inhibitor and Not a Substrate of Human and Mouse P-glycoprotein LD Weidner, KL Fung, P Kannan, JK Moen, JS Kumar, J Mulder, RB Innis, ... Drug Metabolism and Disposition 44 (2), 275-282, 2016 | 87 | 2016 |
An agglutinating chitinase with two chitin-binding domains confers fungal protection in transgenic potato ML Chye, KJ Zhao, ZM He, S Ramalingam, KL Fung Planta 220, 717-730, 2005 | 78 | 2005 |
Mechanical Properties of the Tumor Stromal Microenvironment Probed In Vitro and Ex Vivo by In Situ-Calibrated Optical Trap-Based Active Microrheology JR Staunton, W Vieira, KL Fung, R Lake, A Devine, K Tanner Cellular and molecular bioengineering 9, 398-417, 2016 | 67 | 2016 |
Motesanib (AMG706), a potent multikinase inhibitor, antagonizes multidrug resistance by inhibiting the efflux activity of the ABCB1 YJ Wang, RJ Kathawala, YK Zhang, A Patel, P Kumar, S Shukla, KL Fung, ... Biochemical pharmacology 90 (4), 367-378, 2014 | 64 | 2014 |
Synthesis and characterization of a BODIPY conjugate of the BCR-ABL kinase inhibitor Tasigna (Nilotinib): Evidence for transport of Tasigna and its fluorescent derivative by … S Shukla, AP Skoumbourdis, MJ Walsh, AMS Hartz, KL Fung, CP Wu, ... Molecular Pharmaceutics, 2011 | 63 | 2011 |
Solution structures, dynamics, and lipid‐binding of the sterile α‐motif domain of the deleted in liver cancer 2 H Li, KL Fung, DY Jin, SSM Chung, YP Ching, IO Ng, KH Sze, BCB Ko, ... Proteins: Structure, Function, and Bioinformatics 67 (4), 1154-1166, 2007 | 58 | 2007 |
A dual-fluorescence high-throughput cell line system for probing multidrug resistance KR Brimacombe, MD Hall, DS Auld, J Inglese, CP Austin, MM Gottesman, ... Assay and drug development technologies 7 (3), 233-249, 2009 | 57 | 2009 |
Modeling intrinsic heterogeneity and growth of cancer cells JM Greene, D Levy, KL Fung, PS Souza, MM Gottesman, O Lavi Journal of theoretical biology 367, 262-277, 2015 | 48 | 2015 |
Tobacco-expressed Brassica juncea chitinase BjCHI1 shows antifungal activity in vitro KL Fung, KJ Zhao, ZM He, ML Chye Plant molecular biology 50, 283-294, 2002 | 43 | 2002 |
Expression of the multidrug transporter P-glycoprotein is inversely related to that of apoptosis-associated endogenous TRAIL PS Souza, JP Madigan, JP Gillet, K Kapoor, SV Ambudkar, RC Maia, ... Experimental cell research 336 (2), 318-328, 2015 | 29 | 2015 |
Uptake of Compounds That Selectively Kill Multidrug-Resistant Cells: The Copper Transporter SLC31A1 (CTR1) Increases Cellular Accumulation of the … KL Fung, AK Tepede, KM Pluchino, LM Pouliot, JN Pixley, MD Hall, ... Molecular pharmaceutics 11 (8), 2692-2702, 2014 | 25 | 2014 |
Mitogen-activated protein kinase signaling causes malignant melanoma cells to differentially alter extracellular matrix biosynthesis to promote cell survival A Afasizheva, A Devine, H Tillman, KL Fung, WD Vieira, BH Blehm, ... BMC cancer 16, 1-15, 2016 | 24 | 2016 |
Using the BacMam Baculovirus System to Study Expression and Function of Recombinant Efflux Drug Transporters in Polarized Epithelial Cell Monolayers KL Fung, K Kapoor, JN Pixley, DJ Talbert, ADT Kwit, SV Ambudkar, ... Drug Metabolism and Disposition 44 (2), 180-188, 2016 | 9 | 2016 |
A multiplex immunofluorescence assay to assess immune checkpoint inhibitor-targeted CD8 activation and tumor colocalization in FFPE tissues T Navas, K Fino, KL Fung, F Cutuli, RJ Kinders, A Sharma, GOS Coyne, ... J Clin Oncol 37 (15), 2629, 2019 | 7 | 2019 |
Genetic Polymorphisms of P-glycoprotein: Echoes of Silence KL Fung, RC Hunt, C Kimchi-Sarfaty, MM Gottesman ABC Transporters-40 Years on, 105-134, 2016 | 7 | 2016 |
Expression of an agglutinating chitinase BjCHI1 with two chitin-binding domains is R. solani-inducible and confers fungal protection in transgenic potato ML Chye, KJ Zhao, ZM He, S Ramalingam, KL Fung Planta 220, 717-730, 2005 | 5 | 2005 |
Discrimination of Multidrug Resistance in Different Ovarian Cancer Cells using a Single-Cell Bioanalyzer H Wang, A Khamenehfar, MCK Wong, JLZ Wang, PCH Li, MS Da Zhou, ... Can. J Pure & Appl. Sci 11, 4053-4060, 2017 | 4 | 2017 |